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Journal Articles

RALLY MF: A phase 2 Study of DISC-0974, an anti-hemojuvelin antibody, in patients with myelofibrosis and anemia

Free
Naseema Gangat, Ayalew Tefferi, Prithviraj Bose, Elizabeth Hexner, Laura Michaelis, Aaron Gerds, Akriti Jain, Prioty Islam, Raajit Rampal, Ronan Swords, Moshe Talpaz, Kristen Pettit, Sima Bhatt, Akshay Buch, Olivia Pelletier, Will Savage, Anna Halpern
Journal: Blood
Blood (2025) 146 (Supplement 1): 2042.
https://doi.org/10.1182/blood-2025-2042
Published: 2025
Journal Articles

Bexobrutideg (NX-5948), a novel Bruton's tyrosine kinase (BTK) degrader, demonstrates rapid and durable clinical responses in Relapsed/Refractory chronic lymphocytic leukemia (CLL): New and updated findings from an ongoing Phase 1a/b trial

Free
Zulfa Omer, Alexey Danilov, Francesco Forconi, Talha Munir, Mary Gleeson, Nirav Shah, Graham Collins, Alvaro Alencar, Jane Robertson, Jonathon Cohen, Karan Dixit, Danielle Brander, John Byrd, Allison Winter, Jeffery Smith, Dima El-Sharkawi, Michal Kwiatek, Iwona Hus, Prioty Islam, Sebastian Grosicki, Michael Tees, Thorsten Zenz, Joanna Romejko-Jarosinska, Sarah Injac, Wojciech Jurczak
Journal: Blood
Blood (2025) 146 (Supplement 1): 86.
https://doi.org/10.1182/blood-2025-86
Published: 2025
Journal Articles

Updated results from a Phase II study of minimal residual disease-guided venetoclax + obinutuzumab for the initial treatment of fit patients with chronic lymphocytic leukemia

Free
Meghan Thompson, Anthony Mato, Andrew Zelenetz, Jae Park, Mark Geyer, Andriy Derkach, David Nemirovsky, Deborah Stephens, Catherine Coombs, Prioty Islam, Christopher Jensen, Lorenzo Falchi, Lia Palomba, Anita Kumar, Gilles Salles, Eytan Stein, Jennifer Lue, Lauren Nogan, Bejal Kikani, Ryan Sutterby, Thu Quynh Nguyen, Alexandra Allen, Sumathy Sudhir, Gail Panton, Victoria Duffy, Dianna Tyznar, Jamila Brutus, Tenzin Nyima, Anmol Shah, Dhara Soni, Michael Silvestrone, Monica Shah, Miranda Harris, Megha Karnam, Claire Hutzler, Kevin David, Aaron Goldberg, Stephen Fleming, Giovanni Diaz, Habib Hamidi, Bita Fakhri, Lindsey Roeker
Journal: Blood
Blood (2025) 146 (Supplement 1): 3902.
https://doi.org/10.1182/blood-2025-3902
Published: 2025
Journal Articles

A Phase II multicenter study of minimal residual disease-guided, time-limited acalabrutinib + obinutuzumab for the initial treatment of chronic lymphocytic leukemia

Free
Meghan Thompson, Anthony Mato, Lia Palomba, Lori Leslie, Andriy Derkach, David Nemirovsky, Prioty Islam, Mark Geyer, Philip Caron, Aaron Goldberg, Anita Kumar, Alison Moskowitz, Jennifer Lue, Colette Owens, Gilles Salles, Eytan Stein, Raphael Steiner, Pallawi Torka, Lori Dahncke, Emily Ordona, Mashiyate Meem, Claire Hutzler, Miranda Harris, Monica Shah, Megha Karnam, Lauren Nogan, Caitlin Maloney, Anmol Shah, Tenzin Nyima, Colleen Dorsey, Kate Doyle, Jennifer Howgate-Klingaman, Jamila Brutus, Dianna Tyznar, Anna Lincke, Rick Wray, Tatyana Feldman, Andrew Zelenetz, Lindsey Roeker
Journal: Blood
Blood (2025) 146 (Supplement 1): 5676.
https://doi.org/10.1182/blood-2025-5676
Published: 2025
Journal Articles

A Phase 1b Study of DISC-0974, an Anti-Hemojuvelin Antibody, in Patients with Myelofibrosis and Anemia

Free
Naseema Gangat, James M. Foran, Anna B. Halpern, Raajit Rampal, Prithviraj Bose, Elizabeth O. Hexner, Moshe Talpaz, Laura C. Michaelis, Prioty Islam, Ronan T. Swords, Sima Bhatt, Akshay Buch, Olivia Pelletier, Will Savage, Ayalew Tefferi
Journal: Blood
Blood (2024) 144 (Supplement 1): 657.
https://doi.org/10.1182/blood-2024-203719
Published: 2024
Journal Articles

Minimal Residual Disease (MRD)-Adapted Duration of Front-Line Venetoclax and Obinutuzumab Treatment for Fit Patients with Chronic Lymphocytic Leukemia (CLL)

Free
Lindsey Roeker, Anthony R. Mato, Andrew D. Zelenetz, Jae H. Park, Mark Blaine Geyer, Andriy Derkach, David Nemirovsky, Prioty Islam, Lorenzo Falchi, Maria Lia Palomba, Anita Kumar, Gilles Salles, Jennifer Kimberly Lue, Aaron D. Goldberg, Deborah M. Stephens, Victoria Duffy, Gail Panton, Dianna Tyznar, Colleen Dorsey, Dhara Soni, Claire Hutzler, Lauren Nogan, Alexandra Allen, Tenzin Nyima, Thu Quynh Nguyen, Monica Shah, Tamotha R Cook, Jennifer Abillar-Wright, Jamila Brutus, Carissa Laudati, Bejal Kikani, Catherine C Coombs, Michael R. Silvestrone, Christopher E. Jensen, Bita Fakhri, Meghan C. Thompson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2024-203807
Published: 2024
Journal Articles

A Multi-Center Retrospective Study on Complex Karyotype in Patients with Richter Transformation Who Received No Chemoimmunotherapy for Their CLL

Free
Cecelia Miller, Ying Huang, John N. Allan, Seema A. Bhat, David A. Bond, Danielle M. Brander, John C. Byrd, Julio C. Chavez, Elise A. Chong, Alexey Danilov, Mark R Dowling, Kaitlyn M. Dvorak-Kornaus, Paul J. Hampel, Carrie I Ho, Prioty Islam, Nikita Malakhov, Matthew Matasar, Sarah Miller, Sameer A. Parikh, Kari G. Rabe, Joanna M. Rhodes, Lindsey Roeker, Kerry A. Rogers, Aditi Saha, Alan P Skarbnik, Hamish W Scott, Jake Schade, Mazyar Shadman, Geoffrey Shouse, Deborah M. Stephens, Meghan C. Thompson, Philip A. Thompson, Yucai Wang, Jennifer A. Woyach, Max Yano, Zulfa Omer, Adam S Kittai
Journal: Blood
Blood (2024) 144 (Supplement 1): 3245.
https://doi.org/10.1182/blood-2024-205668
Published: 2024
Journal Articles

Multicenter Phase II Trial of Zanubrutinib, Obinutuzumab, and Venetoclax (BOVen) in Treatment-Naïve Chronic Lymphocytic Leukemia: 5-Year Follow up, Retreatment Outcomes, and Impact of MRD Kinetics (ΔMRD400)

Free
Jacob D. Soumerai, Ahmet Dogan, Venkatraman Seshan, Kelsey Leigh Flaherty, Natalie Slupe, Jason Carter, Ephraim Hochberg, Jeffrey A. Barnes, Jeremy S. Abramson, Audrey Hamilton, Ariela Noy, Colette Owens, Maria Lia Palomba, Anita Kumar, Lindsey Roeker, Meghan C. Thompson, Ronald W. Takvorian, Zachary D. Epstein-Peterson, Mark Blaine Geyer, Gilles Salles, Robert Stuver, Philip Caron, Prioty Islam, Tamanna Haque, Paola Ghione, Raphael E. Steiner, Pallawi Torka, Kevin A. David, Jennifer Kimberly Lue, Paul A. Hamlin, Alison Moskowitz, Lorenzo Falchi, Julie Haydu, Patrick Connor Johnson, Joanna Mi, Jessica Pendleton, Alyssa Labarre, Rosalba Martignetti, Sean F. Plummer, Maria Chabowska, Walter Ramos Amador, Neena Mahajan, Morgan Choma, Clare Grieve, Rayna N. Garcia, Hailey E. Kelly, Ella Mallinger, James O'Grady, Bernadette Beatty, Michelle Adams, Athina Apazidis, Aileen Cleary Cohen, Mina Shahkarami, Allison P. Jacob, Omar Abdel-Wahab, Andrew D. Zelenetz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2024-205697
Published: 2024
Journal Articles

Outcomes of Patients with Richter Transformation without Prior Chemoimmunotherapy for CLL/SLL: An International Multicenter Retrospective Study

Free
Adam S Kittai, Ying Huang, Sarah Miller, John N. Allan, Seema A Bhat, David A. Bond, Danielle M Brander, John C. Byrd, Julio C Chavez, Elise A. Chong, Matthew S Davids, Alexey Danilov, Wei Ding, Mark R Dowling, Kaitlyn M. Dvorak-Kornaus, Hannah Freedman, Paul J Hampel, Carrie I Ho, Steven R Hwang, Prioty Islam, Nitin Jain, Matthew Matasar, Cecelia Miller, Erin M Parry, Kari G. Rabe, Manoj Rai, Phil Raess, Lindsey E. Roeker, Joanna M. Rhodes, Kerry A Rogers, Aditi Saha, Jake Schade, Hamish S Scott, Mazyar Shadman, Geoffrey P. Shouse, Alan Skarbnik, Stephen E Spurgeon, Deborah M. Stephens, Meghan C. Thompson, Philip A. Thompson, Yucai Wang, William G. Wierda, Max Yano, Omer Zulfa, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 497.
https://doi.org/10.1182/blood-2023-182114
Published: 2023
Journal Articles

A Phase 2 Study of Minimal Residual Disease (MRD)-Adapted Front Line Venetoclax and Obinutuzumab in Fit Patients with Chronic Lymphocytic Leukemia (CLL): Effect of Obinutuzumab on Tumor Lysis Syndrome (TLS) Risk and Safety of Outpatient Venetoclax Dose Escalation

Free
Lindsey E. Roeker, Andrew D. Zelenetz, Jae H. Park, Andriy Derkach, Mark Blaine Geyer, Prioty Islam, Lorenzo Falchi, Maria Lia Palomba, Anita Kumar, Gilles Salles, Jennifer Kimberly Lue, Aaron D. Goldberg, Bita Fakhri, Catherine C. Coombs, Victoria Falco, Gail Panton, Dianna Tyznar, Dhara Soni, Lauren Nogan, Sonia Lebowitz, Katherine Blesie, Monica Shah, Sarah Court, Christopher E. Jensen, Anthony R. Mato, Meghan C. Thompson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4657.
https://doi.org/10.1182/blood-2023-181661
Published: 2023
Journal Articles

Female Gender Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplant

Free
Prioty Islam, MD, Haesu Jin, RN, BSN, BMTCN, Felicia Cao, MD PhD, Lauren M. Bohannon, BS, Yi Ren, MS, Nelson J. Chao, MD MBA, Taewoong Choi, MD, Cristina Gasparetto, MD, Mitchell E. Horwitz, MD, Gwynn D. Long, MD, Richard D. Lopez, MD, David A Rizzieri, MD, Stefanie Sarantopoulos, MD PhD, Anthony D. Sung, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-141151
Published: 2020
Journal Articles

PET-Derived Tumor Metrics Predict DLBCL Response and Progression-Free Survival

Free
Prioty Islam, MD MSc, Jordan S. Goldstein, BS, Ila Sethi, MD, Daniel Lee, MD, Christopher Flowers, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4140.
https://doi.org/10.1182/blood.V130.Suppl_1.4140.4140
Published: 2017
Journal Articles

Ibrutinib-induced pneumonitis in patients with chronic lymphocytic leukemia

Free
Anthony R. Mato, Prioty Islam, Catherine Daniel, Lauren Strelec, Adam H. Kaye, Sarah Brooks, Alex Ganetsky, Sunita Nasta, David L. Porter, Jakub Svoboda, Chadi Nabhan, Stephen J. Schuster
Journal: Blood
Blood (2016) 127 (8): 1064–1067.
https://doi.org/10.1182/blood-2015-12-686873
Published: 2016
Journal Articles

Utilization of Next Generation Sequencing Identifies Potentially Actionable Mutations with Prognostic Significance in Chronic Lymphocytic Leukemia

Free
Jie Wang, MD, Jennifer J.D. Morrissette, PhD, E. Paul Wileyto, PhD, Stephen J. Schuster, MD, Alexandra Vandegrift, BA, Allison Rago, BSN, Colleen Dorsey, BSN, David Porter, MD, Daniel J. Landsburg, MD, Prioty Islam, MD, Sunita Dwivedy Nasta, MD, Jakub Svoboda, MD, Alison Loren, MD MS, Scott Weber, BS, Edward A. Stadtmauer, MD, Anthony Mato, MD
Journal: Blood
Blood (2015) 126 (23): 2929.
https://doi.org/10.1182/blood.V126.23.2929.2929
Published: 2015