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Journal Articles

Isatuximab for relapsed and/or refractory AL amyloidosis: results of a prospective phase 2 trial (SWOG S1702)

Free
CME Clinical Trials & Observations
Terri L. Parker, Adam Rosenthal, Vaishali Sanchorawala, Heather J. Landau, Erica L. Campagnaro, Prashant Kapoor, Natalia Neparidze, Saulius Girnius, Patrick Hagen, Emma C. Scott, Antje Hoering, Brian G. M. Durie, Robert Z. Orlowski
Journal: Blood
Blood (2025) 146 (21): 2507–2516.
https://doi.org/10.1182/blood.2024027962
Published: 2025
Journal Articles

Genetic evolution of Waldenström macroglobulinemia across disease stages

Free
Saurabh Zanwar, Joseph Novak, Surendra Dasari, Jonas Paludo, Shaji Kumar, Jansen Seheult, Vaishali Bhardwaj, Miles Del Busso, Ross Miller, Kevin Nowakowski, Dongni Yi, Anne Novak, Thomas Habermann, Shuhei Asada, Patrizia Mondello, Rebecca King, Dragan Jevremovic, Ronald Go, Wilson Gonsalves, Nelson Leung, Angela Dispenzieri, Yi Lin, Taxiarchis Kourelis, S. Vincent Rajkumar, Robert Kyle, Morie Gertz, Stephen Ansell, Prashant Kapoor, Thomas Witzig, Jithma Abeykoon
Journal: Blood
Blood (2025) 146 (Supplement 1): 3540.
https://doi.org/10.1182/blood-2025-3540
Published: 2025
Journal Articles

Prognostic value of immunoparesis, lymphopenia, high serum ferritin, and suppression of the non-involved serum free light chains (niFLC) in relapsed and refractory multiple myeloma patients (RRMM) receiving bispecific antibodies

Free
Valentina Cardenas Castro, Kevin Shim, Mariano Arribas, Justine Wilson-Miller, Adrienne Nedved, Jason Barreto, Mustaqeem Siddiqui, Joselle Cook, Nadine Abdallah, Rahma Warsame, David Dingli, Wilson Gonsalves, Taxiarchis Kourelis, Morie Gertz, Suzanne Hayman, Nelson Leung, Prashant Kapoor, P. Leif Bergsagel, Udit Yadav, J Wiedmeier-Nutor, Saurabh Chhabra, Sikander Ailawadhi, Ricardo Parrondo, Shaji Kumar, S. Vincent Rajkumar, Angela Dispenzieri, Yi Lin, Tyler Sandahl, Rafael Fonseca
Journal: Blood
Blood (2025) 146 (Supplement 1): 5772.
https://doi.org/10.1182/blood-2025-5772
Published: 2025
Journal Articles

The SCOPE trial: A phase 2 Study of selinexor in combination with pomalidomide and dexamethasone for patients with relapsed and/or refractory multiple myeloma

Free
Prashant Kapoor, Morie Gertz, Paul DiZona, Eli Muchtar, Francis Buadi, Wilson Gonsalves, Miriam Hobbs, Amie Fonder, Yi Hwa, Taxiarchis Kourelis, David Dingli, Angela Dispenzieri, Joselle Cook, Suzanne Hayman, Moritz Binder, Nadine Abdallah, Mustaqeem Siddiqui, Rahma Warsame, S. Vincent Rajkumar, Betsy Knopf, Shaji Kumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 2281.
https://doi.org/10.1182/blood-2025-2281
Published: 2025
Journal Articles

An open-label multicenter Phase 1/2 trial of venetoclax-dexamethasone in Relapsed/Refractory t(11;14)-positive systemic AL amyloidosis

Free
Rajshekhar Chakraborty, Anita D'Souza, Prashant Kapoor, Shikun Wang, Divaya Bhutani, Susan Bal, Keith Stockerl-Goldstein, Sherin Selvan, Othman Akhtar, Vaishali Sanchorawala, Suzanne Lentzsch
Journal: Blood
Blood (2025) 146 (Supplement 1): 694.
https://doi.org/10.1182/blood-2025-694
Published: 2025
Journal Articles

Short survival with BCMA and GPRC5D dual antigen exposed relapsed myeloma- an international myeloma working group immunotherapy database analysis

Free
Murali Janakiram, Thomas Martin, Mrugakshi Dave, Chiung-Yu Huang, Sireesha Asoori, Myo Htut, Andre De Menezes Silva Corraes, Prashant Kapoor, Chris Lau Wai Pan, Carlyn Tan, Saad Usmani, Hira Mian, Roman Hajek, Efstathios Kastritis, Susan Bal, Joaquin Martinez-Lopez, Andrew Cowan, Chandramouli Nagarajan, Wee-Joo Chng, Allison Tso, Hermann Einsele, Amrita Krishnan, Rakesh Popat, Yi Lin, Darren Pan
Journal: Blood
Blood (2025) 146 (Supplement 1): 4598.
https://doi.org/10.1182/blood-2025-4598
Published: 2025
Journal Articles

Machine learning–driven prognostication of overall survival at 6 months after CAR-T cell therapy

Free
Jonas Paludo, Jacob Shreve, Emmanuel Contreras Guzman, Arushi Khurana, Prashant Kapoor, Morie Gertz, Yucai Wang, Moritz Binder, Jose Villasboas Bisneto, N. Nora Bennani, Patrick Johnston, Talal Hilal, Madiha Iqbal, Muhamad Alhaj Moustafa, Ricardo Parrondo, Saurabh Chhabra, Shaji Kumar, Stephen Ansell, Allison Rosenthal, Mohamed Kharfan-Dabaja, Tufia Haddad, Yi Lin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2563.
https://doi.org/10.1182/blood-2025-2563
Published: 2025
Journal Articles

Clinical course, predictors of development, and therapeutic response in multiple myeloma with central nervous system involvement

Free
Alexander Xiao, Saurabh Zanwar, Yi Lin, Prashant Kapoor, Nadine Abdallah, Moritz Binder, Francis Buadi, Angela Dispenzieri, David Dingli, Amie Fonder, Morie Gertz, Wilson Gonsalves, Suzanne Hayman, Yi Hwa, Miriam Hobbs, Taxiarchis Kourelis, Martha Lacy, Nelson Leung, Eli Muchtar, Mustaqeem Siddiqui, Melinda Tan, Rahma Warsame, Dragan Jevremovic, Robert Kyle, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 2225.
https://doi.org/10.1182/blood-2025-2225
Published: 2025
Journal Articles

Cytogenetics-based clinical trajectories of patients with MRD negativity post autologous stem cell transplant for multiple myeloma

Free
Estefania Gauto Mariotti, Shaji Kumar, Wilson Gonsalves, Prashant Kapoor, Angela Dispenzieri, Francis Buadi, David Dingli, Dragan Jevremovic, Suzanne Hayman, Nelson Leung, Joselle Cook, Nadine Abdallah, Moritz Binder, Eli Muchtar, Rahma Warsame, Taxiarchis Kourelis, Ronald Go, Yi Hwa, Miriam Hobbs, Amie Fonder, Mustaqeem Siddiqui, Yi Lin, Robert Kyle, Morie Gertz, S. Vincent Rajkumar, Saurabh Zanwar
Journal: Blood
Blood (2025) 146 (Supplement 1): 362.
https://doi.org/10.1182/blood-2025-362
Published: 2025
Journal Articles

S2005: A phase II randomized study comparing ibrutinib and rituximab (IR) VS. venetoclax and rituximab (VR) in previously untreated waldenstrom's macroglobulinemia (WM) / lymphoplasmacytic lymphoma (LPL).

Free
Sikander Ailawadhi, Divaya Bhutani, Antje Hoering, Adam Rosenthal, J Christine Ye, Prashant Kapoor, Saad Usmani, Manisha Bhutani, S. Vincent Rajkumar, Paul Gater, Robert Orlowski
Journal: Blood
Blood (2025) 146 (Supplement 1): 1840.
https://doi.org/10.1182/blood-2025-1840
Published: 2025
Journal Articles

Patterns of progression and clinical outcomes after first relapse in patients with primary plasma cell leukemia

Free
Daniel Packard, Shaji Kumar, Tamer Hellou, Prashant Kapoor, Angela Dispenzieri, Francis Buadi, David Dingli, Saurabh Zanwar, Dragan Jevremovic, Suzanne Hayman, Nelson Leung, Joselle Cook, Nadine Abdallah, Moritz Binder, Eli Muchtar, Rahma Warsame, Taxiarchis Kourelis, Ronald Go, Yi Hwa, Miriam Hobbs, Amie Fonder, Yi Lin, Morie Gertz, S. Vincent Rajkumar, Wilson Gonsalves
Journal: Blood
Blood (2025) 146 (Supplement 1): 1036.
https://doi.org/10.1182/blood-2025-1036
Published: 2025
Journal Articles

Clinical, anatomic, and histologic determinants of gastrointestinal disease burden and survival in systemic AL amyloidosis: A cohort study of 560 patients

Free
Max Steinhardt, Eli Muchtar, Taxiarchis Kourelis, Rahma Warsame, Michelle Mauermann, Francis Buadi, David Dingli, Nelson Leung, Joselle Cook, Ronald Go, Suzanne Hayman, Wilson Gonsalves, Prashant Kapoor, Saurabh Zanwar, Moritz Binder, Tamer Hellou, Melinda Tan, Amie Fonder, Miriam Hobbs, Nadine Abdallah, Yi Lin, Mustaqeem Siddiqui, Robert Kyle, Hermann Einsele, S. Vincent Rajkumar, Shaji Kumar, K. Martin Kortüm, Morie Gertz, Angela Dispenzieri
Journal: Blood
Blood (2025) 146 (Supplement 1): 3962.
https://doi.org/10.1182/blood-2025-3962
Published: 2025
Journal Articles

Cardiac complete response in AL amyloidosis: Phenotypic characteristics, functional recovery, and survival outcomes of 63 patients

Free
Eli Muchtar, Susan Geyer, Angela Dispenzieri, Martha Grogan, Taxiarchis Kourelis, Francis Buadi, Prashant Kapoor, David Dingli, Wilson Gonsalves, Nelson Leung, Giampaolo Merlini, Julie Rosenthal, Melissa Lyle, Suzanne Hayman, Martha Lacy, Mustaqeem Siddiqui, Joselle Cook, Nadine Abdallah, Moritz Binder, Saurabh Zanwar, Yi Lin, Rahma Warsame, Robert Kyle, S. Vincent Rajkumar, Shaji Kumar, Morie Gertz
Journal: Blood
Blood (2025) 146 (Supplement 1): 3960.
https://doi.org/10.1182/blood-2025-3960
Published: 2025
Journal Articles

Self-reported geriatric impairments and treatment toxicity in older patients with multiple myeloma - a single center prospective study

Free
Rosalyn Marar, Claire Yee, Anna Bodily, Tanya Wildes, Terri Menser, Megan Weivoda, Sarah Aug, Francis Buadi, Wilson Gonsalves, Prashant Kapoor, Angela Dispenzieri, Suzanne Hayman, Eli Muchtar, David Dingli, Joselle Cook, Saurabh Zanwar, Moritz Binder, Taxiarchis Kourelis, Morie Gertz, Rahma Warsame, Yi Lin, S. Vincent Rajkumar, Amylou Dueck, Shaji Kumar, Nadine Abdallah
Journal: Blood
Blood (2025) 146 (Supplement 1): 715.
https://doi.org/10.1182/blood-2025-715
Published: 2025
Journal Articles

Deep responses following treatment with loncastuximab tesirine (WM-NET1 trial) in patients with Relapsed/Refractory including those withhigh-risk, TP53-altered Waldenström macroglobulinemia.

Free
Shayna Sarosiek, Mary Kwok, Prashant Kapoor, Hannah Chory, Nina Budano, Julia Nguyen, Alexandra Eurell, Kirsten Meid, Alberto Guijosa, Nickolas Tsakmaklis, Zachary Hunter, Andrew Branagan, Steven Treon, Jorge Castillo
Journal: Blood
Blood (2025) 146 (Supplement 1): 581.
https://doi.org/10.1182/blood-2025-581
Published: 2025
Journal Articles

Prophylactic dexamethasone to reduce risk of cilta-cel associated immune effector cell delayed neurotoxicity

Free
Kenneth JC Lim, Ricardo Parrondo, Saurabh Chhabra, Katharine Dooley, Andre De Menezes Silva Corraes, Darin Carabenciov, Morie Gertz, Yi Hwa, Haily Stephens, Prashant Kapoor, Melinda Tan, Taxiarchis Kourelis, Rahma Warsame, Joselle Cook, Moritz Binder, P. Leif Bergsagel, Udit Yadav, J Wiedmeier-Nutor, Susan Geyer, Saurabh Zanwar, Nadine Abdallah, Sikander Ailawadhi, Rafael Fonseca, Shaji Kumar, Anastasia Zekeridou, Yi Lin
Journal: Blood
Blood (2025) 146 (Supplement 1): 5953.
https://doi.org/10.1182/blood-2025-5953
Published: 2025
Journal Articles

Large language model for abstraction of CAR-T therapy toxicities data

Free
Kayla Joseph, Andre De Menezes Silva Corraes, Emmanuel Contreras Guzman, Melinda Tan, Monica Shaw, Jody Mclean, Kimberly Riester, Matthew Jankowski, Ramona Bruno, Lucy Holmes, Allison Burgstahler, N. Nora Bennani, Morie Gertz, Paul Hampel, Prashant Kapoor, Saad Kenderian, Arushi Khurana, Taxiarchis Kourelis, Nelson Leung, Mithun Shah, Rahma Warsame, Urshila Durani, Shaji Kumar, Stephen Ansell, Hassan Alkhateeb, Matthew Hathcock, Yucai Wang, Patrick Johnston, Jonas Paludo, Yi Lin
Journal: Blood
Blood (2025) 146 (Supplement 1): 6139.
https://doi.org/10.1182/blood-2025-6139
Published: 2025
Journal Articles

Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Transformed Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: a DESCAR-T Registry and International Collaborative Study

Free
Eric Durot, Lukshe Kanagaratnam, Sylvain Choquet, Pierre Sesques, Jehan Dupuis, Thomas Gastinne, Peter Forsberg, Emmanuel Gyan, Adrien Chauchet, Justine Decroocq, Roberta Di Blasi, Hedi Bensaber, Caroline Jacquet, Morgane Cheminant, Stephanie Guidez, François-Xavier Gros, Lucile Bussot, Steeve Chevreux, Thomas Hueso, Gabriel Brisou, Arnaud Campidelli, Elodie Gat, Simone Ferrero, Anna Maria Frustaci, Marzia Varettoni, Charalampia Kyriakou, Steven Treon, Prashant Kapoor, Ran Reshef, Jorge Castillo, Emmanuel Bachy, Roch Houot, Damien Roos Weil
Journal: Blood
Blood (2025) 146 (Supplement 1): 5490.
https://doi.org/10.1182/blood-2025-5490
Published: 2025
Journal Articles

Real-world (RW) outcomes of newly diagnosed multiple myeloma (NDMM) patients (pts) treated with front-line daratumumab (dara), bortezomib (bor), lenalidomide (len) and dexamethasone (dex) (DVRd)

Free
Ricardo Parrondo, Ricardo de Menezes, Hanna Sledge, Kanika Yadav, Madhavi Nayyar, P. Leif Bergsagel, Rafael Fonseca, Prashant Kapoor, Francis Buadi, Morie Gertz, Angela Dispenzieri, Vivek Roy, Taimur Sher, Moritz Binder, Nadine Abdallah, Saurabh Chhabra, S. Vincent Rajkumar, Wilson Gonsalves, Joselle Cook, David Dingli, Yi Lin, Eli Muchtar, Caitlin Flott, Udit Yadav, Rahma Warsame, J Wiedmeier-Nutor, Taxiarchis Kourelis, Nelson Leung, Mustaqeem Siddiqui, Andre Fernandez, Shaji Kumar, Asher Chanan-Khan, Sikander Ailawadhi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4585.
https://doi.org/10.1182/blood-2025-4585
Published: 2025
Journal Articles

Disease characteristics, treatment patterns, and outcomes of AL amyloidosis patients with high-risk FISH cytogenetics

Free
Tamer Hellou, Estefania Gauto Mariotti, Ahmed Alnughmush, Daniel Packard, Max Steinhardt, Morie Gertz, Angela Dispenzieri, Dragan Jevremovic, Linda Baughn, Francis Buadi, David Dingli, Taxiarchis Kourelis, Saurabh Zanwar, Suzanne Hayman, Prashant Kapoor, Nelson Leung, Yi Hwa, Amie Fonder, Miriam Hobbs, Rahma Warsame, Joselle Cook, Moritz Binder, Nadine Abdallah, Yi Lin, Ronald Go, Mustaqeem Siddiqui, Robert Kyle, S. Vincent Rajkumar, Wilson Gonsalves, Shaji Kumar, Eli Muchtar
Journal: Blood
Blood (2025) 146 (Supplement 1): 5741.
https://doi.org/10.1182/blood-2025-5741
Published: 2025