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Anna Maria Frustaci
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Journal Articles

Venetoclax-based therapy remodels T-cell and NK-cell immunity in patients with chronic lymphocytic leukemia

Free
Giorgia Mancin, Valentina Griggio, Rebecca Jones, Giulia Bondielli, Andrea Visentin, Riccardo Moia, Anna Maria Frustaci, Alessandro Bosi, Marzia Varettoni, Francesca Perutelli, Maria Chiara Montalbano, Gioacchino Catania, Paolo Sportoletti, Luca Laurenti, Francesca Mauro, Lorella Orsucci, Luca Arcaini, Francesco Passamonti, Marina Deodato, Gianluca Gaidano, Livio Trentin, Benedetto Bruno, Candida Vitale, Marta Coscia
Journal: Blood
Blood (2025) 146 (Supplement 1): 5657.
https://doi.org/10.1182/blood-2025-5657
Published: 2025
Journal Articles

ZUMA-25 preliminary analysis: A Phase 2 study of brexucabtagene autoleucel (brexu-cel) in patients (Pts) with relapsed/refractory (R/R) burkitt lymphoma (BL), substudy C

Free
Suzanne Van Dorp, Georg Stussi, Anna Maria Frustaci, Ian Flinn, Zachary Crees, John Baird, Luke Mountjoy, Saurabh Dahiya, Nadine Kutsch, Pier Luigi Zinzani, Armando Lopez-Guillermo, Philipp Staber, Loic Ysebaert, Ramon Garcia-Sanz, Fatima De la Cruz Vicente, Lori Leslie, David Bond, Bhagirathbhai Dholaria, Chad Williams, Lang Zhou, Ioana Kloos, Liana Nikolaenko, Enrico Tiacci
Journal: Blood
Blood (2025) 146 (Supplement 1): 569.
https://doi.org/10.1182/blood-2025-569
Published: 2025
Journal Articles

TP53 mutations in paired bone marrow and cell-free DNA samples of patients with Waldenström macroglobulinemia or IgM monoclonal gammopathy of undetermined significance prospectively enrolled in the FIL_biowm study of fondazione italiana linfomi

Free
Marzia Varettoni, Silvia Zibellini, Daniela Drandi, Chiara Varraso, Emilia Cappello, Luigi Marcheselli, Irene Dogliotti, Federica Cavallo, Angela Ferrari, Enrico Amaducci, Michele Merli, Anna Maria Frustaci, Luca Laurenti, Simona Tomassetti, Emanuele Cencini, Giacomo Loseto, Silvia Finotto, Monia Marchetti, Francesca Re, Antonello Sica, Jacopo Olivieri, Gianmarco Favrin, Cristina Jimenez, Giulia Benevolo, Ramon Garcia-Sanz, Luca Arcaini, Simone Ferrero
Journal: Blood
Blood (2025) 146 (Supplement 1): 5318.
https://doi.org/10.1182/blood-2025-5318
Published: 2025
Journal Articles

Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Transformed Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma: a DESCAR-T Registry and International Collaborative Study

Free
Eric Durot, Lukshe Kanagaratnam, Sylvain Choquet, Pierre Sesques, Jehan Dupuis, Thomas Gastinne, Peter Forsberg, Emmanuel Gyan, Adrien Chauchet, Justine Decroocq, Roberta Di Blasi, Hedi Bensaber, Caroline Jacquet, Morgane Cheminant, Stephanie Guidez, François-Xavier Gros, Lucile Bussot, Steeve Chevreux, Thomas Hueso, Gabriel Brisou, Arnaud Campidelli, Elodie Gat, Simone Ferrero, Anna Maria Frustaci, Marzia Varettoni, Charalampia Kyriakou, Steven Treon, Prashant Kapoor, Ran Reshef, Jorge Castillo, Emmanuel Bachy, Roch Houot, Damien Roos Weil
Journal: Blood
Blood (2025) 146 (Supplement 1): 5490.
https://doi.org/10.1182/blood-2025-5490
Published: 2025
Journal Articles

International consensus statement on diagnosis, evaluation, and research of Richter transformation: the ERIC recommendations

Free
Adam S. Kittai, Monia Marchetti, Othman Al-Sawaf, Ohad Benjamini, Alexey V. Danilov, Matthew S. Davids, Barbara Eichhorst, Toby A. Eyre, Anna Maria Frustaci, Michael Hallek, Paul J. Hampel, Yair Herishanu, Rodney J. Hicks, Arnon P. Kater, Rebecca L. King, Jose I. Martin-Subero, Carolyn Owen, Erin Parry, Maurilio Ponzoni, Davide Rossi, Tanya Siddiqi, Stephan Stilgenbauer, Constantine S. Tam, Elisa ten Hacken, Philip A. Thompson, William Wierda, Gianluca Gaidano, Jennifer A. Woyach, Paolo Ghia
Journal: Blood
Blood (2025) 146 (3): 291–303.
https://doi.org/10.1182/blood.2024028064
Published: 2025
Includes: Supplemental data
Journal Articles

Triplets: the bright and the dark side of the moon

Free
Clinical Trials & Observations
Anna Maria Frustaci, Alessandra Tedeschi
Journal: Blood
Blood (2025) 145 (12): 1229–1231.
https://doi.org/10.1182/blood.2024028110
Published: 2025
Journal Articles

Acalabrutinib in High-Risk Chronic Lymphocytic Leukemia Patients Naïve or Previous Treated. a Multicenter Retrospective Observational Real-Life Experience

Free
Idanna Innocenti, Annamaria Tomasso, Diana Giannarelli, Lydia Scarfo, Roberta Murru, Andrea Visentin, Anna Maria Frustaci, Francesca Morelli, Candida Vitale, Antonio Mosca, Alessandro Sanna, Giuliana Farina, Roberta Laureana, Massimo Gentile, Andrea Galitzia, Raffaella Pasquale, Francesco Autore, Jacopo Olivieri, Azzurra Anna Romeo, Marina Deodato, Luca Stirparo, Andrea Corbingi, Vanessa Innao, Francesca Perutelli, Francesca Martini, Paolo Sportoletti, Alberto Fresa, Maria Ilaria Del Principe, Alessandra Tedeschi, Marta Coscia, Paolo Ghia, Luca Laurenti
Journal: Blood
Blood (2024) 144 (Supplement 1): 6798.
https://doi.org/10.1182/blood-2024-203557
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of the Bruton Tyrosine Kinase Degrader BGB-16673 in Patients with Relapsed or Refractory (R/R) Indolent NHL: Results from the Phase 1 CaDAnCe-101 Study

Free
Constantine S. Tam, Anna Maria Frustaci, Fontanet Bijou, Pier Luigi Zinzani, John F. Seymour, Masa Lasica, Herbert A. Eradat, Victor T.G. Lin, Maan Alwan, Irina Mocanu, Xiangmei Chen, Kunthel By, Shannon Fabre, Daniel O. Persky, Amit Agarwal, Chan Y. Cheah
Journal: Blood
Blood (2024) 144 (Supplement 1): 1649.
https://doi.org/10.1182/blood-2024-199154
Published: 2024
Journal Articles

Ibrutinib or Chemo-Immunotherapy As Second Line Treatment in Waldenstrom Macroglobulinaemia? a Real-Life Multicentre Study

Free
Francesco Autore, Alessandra Tedeschi, Giulia Benevolo, Nicolò Danesin, Diana Giannarelli, Rita Rizzi, Emanuele Cencini, Veronica Mattiello, Isacco Ferrarini, Jacopo Olivieri, Ilaria Del Giudice, Angela Ferrari, Martina Bullo, Bernardo Rossini, Marina Motta, Dario Marino, Idanna Innocenti, Luca Stirparo, Diego Petrilli, Pellegrino Musto, Veronica Peri, Giulia Zamprogna, Stefan Hohaus, Anna Maria Frustaci, Francesco Piazza, Simone Ferrero, Luca Laurenti
Journal: Blood
Blood (2024) 144 (Supplement 1): 3013.
https://doi.org/10.1182/blood-2024-200111
Published: 2024
Journal Articles

Treatment with Venetoclax Positively Modulates Immunological Parameters and T-Cell Features in Patients with Chronic Lymphocytic Leukemia

Free
Valentina Griggio, Candida Vitale, Rebecca Jones, Giorgia Mancin, Giulia Bondielli, Andrea Visentin, Riccardo Moia, Anna Maria Frustaci, Veronica Mattiello, Marzia Varettoni, Francesca Perutelli, Maria Chiara Montalbano, Giacomo Ortone, Gioacchino Catania, Paolo Sportoletti, Luca Laurenti, Francesca Romana Mauro, Lorella Orsucci, Luca Arcaini, Francesco Passamonti, Marina Deodato, Gianluca Gaidano, Livio Trentin, Benedetto Bruno, Marta Coscia
Journal: Blood
Blood (2024) 144 (Supplement 1): 1854.
https://doi.org/10.1182/blood-2024-203053
Published: 2024
Journal Articles

Comparison of Familial Versus Sporadic Forms of Chronic Lymphocytic Leukemia: An Italian Multicenter Case-Control Study

Free
Alberto Fresa, Idanna Innocenti, Annamaria Tomasso, Candida Vitale, Alessandro Sanna, Anna Maria Frustaci, Andrea Visentin, Azzurra Anna Romeo, Paolo Sportoletti, Annamaria Giordano, Francesca Perutelli, Roberta Murru, Francesca Romana Mauro, Antonio Mosca, Francesca Morelli, Roberta Laureana, Andrea Galitzia, Ilaria Angeletti, Esmeralda Conte, Riccardo Moia, Giovanni Francesco D'Arena, Raffaella Pasquale, Francesco Autore, Jacopo Olivieri, Luca Stirparo, Giulia Benintende, Andrea Corbingi, Maria Ilaria Del Principe, Diana Giannarelli, Alessandra Tedeschi, Marta Coscia, Eugenio Sangiorgi, Dimitar G Efremov, Luca Laurenti
Journal: Blood
Blood (2024) 144 (Supplement 1): 4621.
https://doi.org/10.1182/blood-2024-205215
Published: 2024
Journal Articles

Adaptation of Chronic Lymphocytic Leukemia to Ibrutinib Is Mediated By Epigenetic Plasticity of Residual Disease and By-Pass Signaling Via MAPK Pathway

Free
Lodovico Terzi Di Bergamo, Gabriela Forestieri, Jui Wan Loh, Amartya Singh, Valeria Spina, Federico Jauk, Antonella Zucchetto, Adalgisa Condoluci, Alessio Bruscaggin, Katia Pini, Deborah Piffaretti, Elisa Civanelli, Chiara Tarantelli, Matin Salehi, Ilaria Romano, Maria Cristina Pirosa, Simone Bocchetta, Georgia Alice Galimberti, Tamara Bittolo, Erika Tissino, Lorenzo De Paoli, Clara Deambrogi, Anna Maria Frustaci, Francesco Autore, Michele Merli, Lydia Scarfo, Silvia Rasi, Marina Deodato, Jakob Passweg, Sr., Riccardo Moia, Claudio Martines, Paolo Ghia, Franco Cavalli, Emanuele Zucca, Bernhard Gerber, Georg Stüssi, Marco Montillo, Francesco Passamonti, Michael Gregor, Luca Laurenti, Alessandra Tedeschi, Alexandar Tzankov, Francesco Bertoni, Gianluca Gaidano, Dimitar G Efremov, Valter Gattei, Hossein Khiabanian, Davide Rossi
Journal: Blood
Blood (2024) 144 (Supplement 1): 73.
https://doi.org/10.1182/blood-2024-205557
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of the Bruton Tyrosine Kinase Degrader BGB-16673 in Patients with Relapsed or Refractory Waldenström Macroglobulinemia: Results from the Phase 1 CaDAnCe-101 Study

Free
John F. Seymour, Constantine S. Tam, Chan Y. Cheah, Ricardo D. Parrondo, John N. Allan, Judith Trotman, Ranjana H. Advani, Herbert A. Eradat, Pier Luigi Zinzani, Masa Lasica, Steven P. Treon, Xiangmei Chen, Kunthel By, Shannon Fabre, Daniel O. Persky, Amit Agarwal, Anna Maria Frustaci
Journal: Blood
Blood (2024) 144 (Supplement 1): 860.
https://doi.org/10.1182/blood-2024-199212
Published: 2024
Journal Articles

Preliminary Efficacy and Safety of the Bruton Tyrosine Kinase Degrader BGB-16673 in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Results from the Phase 1 CaDAnCe-101 Study

Free
Meghan C. Thompson, Ricardo D. Parrondo, Anna Maria Frustaci, John N. Allan, Paolo Ghia, Irina Mocanu, Constantine S. Tam, Judith Trotman, Inhye E. Ahn, Stephan Stilgenbauer, Lydia Scarfo, Xiangmei Chen, Kunthel By, Shannon Fabre, Daniel O. Persky, Amit Agarwal, John F. Seymour
Journal: Blood
Blood (2024) 144 (Supplement 1): 885.
https://doi.org/10.1182/blood-2024-199116
Published: 2024
Journal Articles

COVID-19 Pandemic Impact on Chronic Lymphocytic Leukemia (CLL) Patients' Preferences Towards Therapies: The Italian Experience (CHOICE Study)

Free
Stefano Molica, Luca Laurenti, Paolo Ghia, Marta Coscia, Antonio Cuneo, Gianluca Gaidano, Francesca Mauro, Anna Maria Frustaci, Daniele Vallisa, Fabrizio Pane, Giuliana Gualberti, Emilia Iannella, Paola Finsinger, Morena Caira, Paolo Sportoletti
Journal: Blood
Blood (2021) 138 (Supplement 1): 4690.
https://doi.org/10.1182/blood-2021-148308
Published: 2021
Journal Articles

Common Gene Expression Signature of B-Cells of Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathies of Undetermined Significance ( IgM MGUS ) Compared to Healthy Subjects

Free
Alessandra Trojani, Barbara Di Camillo, Luca Emanuele Bossi, Antonino Greco, Livia Leuzzi, Alessandra Tedeschi, Anna Maria Frustaci, Marina Deodato, Giulia Zamprogna, Agostina Melluso, Alessia Panzeri, Marco Montillo, Alessandro Beghini, Roberto Cairoli
Journal: Blood
Blood (2021) 138 (Supplement 1): 4317.
https://doi.org/10.1182/blood-2021-147712
Published: 2021
Journal Articles

Do Age, Fitness and Concomitant Medications Influence Management and Outcomes of CLL Patients Treated with Ibrutinib?

Free
Alessandra Tedeschi, MD, Anna Maria Frustaci, MD, Francesca Romana Mauro, MD, Annalisa Chiarenza, MD PhD, Marta Coscia, MD PhD, Stefania Ciolli, Gianluigi Reda, MD, Luca Laurenti, MD, Marzia Varettoni, Roberta Murru, MD, Claudia Baratè, MD, Paolo Sportoletti, MD, Antonino Greco, MD, Chiara Borella, MD, Valentina Rossi, MD, Marina Deodato, MD, Annalisa Biagi, MD, Angelo Curto Pelle, MD, Gianfranco Lapietra, MD, Candida Vitale, MDPhD, Francesca Morelli, MD, Ramona Cassin, MD, Alberto Fresa, MD, Elena Flospergher, MD, Massimiliano Postorino, MD, Alessio Di Prima, MD, Roberto Cairoli, MD, Francesco Di Raimondo, MD, Marco Montillo, Giovanni Del Poeta, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 54–55.
https://doi.org/10.1182/blood-2020-137024
Published: 2020
Journal Articles

Role of Age, Fitness and Concomitant Medications in CLL Patients Treated with Venetoclax

Free
Anna Maria Frustaci, Annalisa Biagi, MD, Annalisa Chiarenza, MD PhD, Marta Coscia, MD PhD, Stefania Ciolli, Luca Laurenti, MD, Paolo Sportoletti, MD, Gianluigi Reda, MD, Marzia Varettoni, Francesca Romana Mauro, MD, Roberta Murru, MD, Claudia Baratè, MD, Antonino Greco, MD, Chiara Borella, MD, Giulia Zamprogna, MD, Enrica Antonia Martino, MD, Candida Vitale, MDPhD, Francesca Morelli, MD, Alberto Fresa, MD, Valerio Guarente, MD, Alessandro Noto, MD, Massimiliano Postorino, MD, Roberto Cairoli, MD, Marco Montillo, Giovanni Del Poeta, MD, Alessandra Tedeschi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-137202
Published: 2020
Journal Articles

Health-Related Quality of Life in Waldenstrom Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undeterminated Significance (IgM-MGUS)

Free
Anna Maria Frustaci, Michele Nichelatti, PhD, Marina Deodato, MD, Maddalena Mazzucchelli, MD, Marco Montillo, MD, Roberto Cairoli, Alessandra Tedeschi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3593.
https://doi.org/10.1182/blood-2018-99-111444
Published: 2018
Journal Articles

Mechanisms of Adaptation to Ibrutinib in High Risk Chronic Lymphocytic Leukemia

Free
Valeria Spina, PhD, Gabriela Forestieri, Antonella Zucchetto, Alessio Bruscaggin, PhD, Tamara Bittolo, PhD, Lodovico Terzi di Bergamo, Eva Szenes, Adalgisa Condoluci, MD, Erika Tissino, PhD, Lorenzo De Paoli, MD, Clara Deambrogi, PhD, Anna Maria Frustaci, Francesco Autore, MD, Michele Merli, MD, Lydia Scarfo, MD, Claudia Cirillo Sanchez, Francesca Guidetti, Simone Favini, Fary Diop, Renzo Lucchini, Tanja N. Hartmann, PhD, Giovanni Del Poeta, MD, Roberto Marasca, MD, Francesco Zaja, Bernhard Gerber, Emanuele Zucca, Georg Stussi, MD, Jakob R. Passweg, MDMS, Paolo Ghia, MD PhD, Francesco Passamonti, MD, Michael Gregor, MD, Luca Laurenti, MD, Marco Montillo, MD, Alessandra Tedeschi, MD, Franco Cavalli, MD, Gianluca Gaidano, MD PhD, Valter Gattei, MD, Davide Rossi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 585.
https://doi.org/10.1182/blood-2018-99-116739
Published: 2018