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Journal Articles

CDK7 enables adaptive gene transcription required by stromal cells to support distinct T-cell lymphoma phenotypes and represents a novel microenvironment-directed therapeutic target

Khouloud Kouidri, Danilo Fiore, María Revuelta, Nicolás Di Siervi, Federico Ruiz Moreno, Subhashini Joshi, Clarisse Kayembe, Abigail Taylor, Giorgio Inghirami, Leandro Cerchietti, Nahuel Zamponi

Blood (2025) 146 (Supplement 1): 554.

https://doi.org/10.1182/blood-2025-554

Published: 2025

Journal Articles

Adenosine pathway as a therapeutic target in diffuse large B cell lymphoma

Maria Aguilar-Hernandez, Miranda Mcgaskey, Anabelle Ouedraogo, Vicenta Trujillo-Alonso, Sophia Zelizer, Rachel Ng, Giorgio Inghirami, Roberta Zappasodi, Ethel Cesarman

Blood (2025) 146 (Supplement 1): 5345.

https://doi.org/10.1182/blood-2025-5345

Published: 2025

Journal Articles

Gene-regulatory axes of diffuse large B-cell lymphoma subtypes

Julius Enssle, Boya Wang, George Wright, Xin Yu, James Phelan, Yandan Yang, Arthur Shaffer, Da Wei Huang, Zana Coulibaly, Michael Kelly, Bao Tran, Stefania Pittaluga, Mark Roschewski, Wyndham Wilson, Thomas Oellerich, Giorgio Inghirami, Louis Staudt

Blood (2025) 146 (Supplement 1): 5313.

https://doi.org/10.1182/blood-2025-5313

Published: 2025

Journal Articles

A phase 1b trial of the EZH2 inhibitor tazemetostat combined with CAR T cell therapy in B cell lymphomas

Samuel Yamshon, Caitlin Gribbin, Yusuke Isshiki, Ioannis Karagiannidis, Sunjae Lee, Jizhi Yan, Gwynne Ozkan, Anna Alperovich, Barbara Ma, Christopher Hackett, Mateo Mejia-Saldarriaga, Daniel Choi, Selina Chen-Kiang, John Leonard, Ari Melnick, Juliet Barker, Giorgio Inghirami, Wendy Béguelin, Peter Martin

Blood (2025) 146 (Supplement 1): 1011.

https://doi.org/10.1182/blood-2025-1011

Published: 2025

Journal Articles

Primary central nervous system lymphoma reveals a pro-tumoral brain-specific myeloid landscape.

Subhashini Joshi, María Revuelta, Nahuel Zamponi, Khouloud Kouidri, Federico Ruiz Moreno, Giorgio Inghirami, Ari Melnick, Leandro Cerchietti

Blood (2025) 146 (Supplement 1): 145.

https://doi.org/10.1182/blood-2025-145

Published: 2025

Journal Articles

Sasp-driven immune evasion defines a novel African ancestry-associated DLBCL subtype with distinctive molecular and immune vulnerabilities

Blood (2025) 146 (Supplement 1): 3.

https://doi.org/10.1182/blood-2025-3

Published: 2025

Journal Articles

Humanized PDX models reveal Lymphoma–Host interactions and enhanced T-cell therapies via epigenetic modulation

Blood (2025) 146 (Supplement 1): 350.

https://doi.org/10.1182/blood-2025-350

Published: 2025

Journal Articles

Real-world impact of differences in the WHO and ICC classifications of non-Hodgkin lymphoma: a LEO cohort study analysis

Blood (2024) 144 (19): 2063–2066.

https://doi.org/10.1182/blood.2024025681

Published: 2024

Includes: Supplemental data

Journal Articles

Biological and Prognostic Subgroups of Plasmablastic Lymphoma Defined By EBV Status and MYC Rearrangement- an L.L.M.P.P. Study

Blood (2024) 144 (Supplement 1): 231.

https://doi.org/10.1182/blood-2024-208880

Published: 2024

Journal Articles

An Llmpp Study: Genomic Characterization of Novel PTCL- Biological Subtypes Reveal Distinctive Therapeutic Vulnerabilities

Blood (2024) 144 (Supplement 1): 456.

https://doi.org/10.1182/blood-2024-209396

Published: 2024

Journal Articles

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Andrew L. Feldman, Guangzhen Hu, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Jimena B. Gimenez, Farah M. Salama, Min Shi, Elías Campo, Wing Chung Chan, James R. Cook, Giorgio Inghirami, Elaine S. Jaffe, Ryan Morin, Phillipp W. Raess, Andreas Rosenwald, Kerry J. Savage, Louis M. Staudt, George W. Wright, Catalina Amador, Jan Delabie, Timothy C. Greiner, Javeed Iqbal, Laura K. Hilton, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Graham W. Slack, Susan L. Slager, Joo Y. Song, Hao-Wei Wang, Ahmed A. Aljudi, Stephen M. Ansell, Carlos Barrionuevo, James R. Cerhan, Jennifer R. Chapman-Fredricks, Weina Chen, Laurence de Leval, Alejandro A. Gru, David L. Jaye, Liuyan Jiang, Brad S. Kahl, Kennosuke Karube, Young Hyeh Ko, Eric Mou, Matthew J. Maurer, L. Jeffrey Medeiros, Roberto N. Miranda, Naoki Oishi, Perry M. Anamarija, Akira Satou, Xueju Wang, Ryan A. Wilcox, Xiaojun Wu, Tadashi Yoshino, Yu Zeng

Blood (2024) 144 (Supplement 1): 2974.

https://doi.org/10.1182/blood-2024-202410

Published: 2024

Journal Articles

Subsequent Treatment and Clinical Outcome Following Induction Therapy on a Phase II Study of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL)

Jia Ruan, Evelyn H. Orlando, Alison Moskowitz, Zhengming Chen, Neha Mehta-Shah, Lubomir Sokol, Steven Horwitz, Sarah C. Rutherford, Tejasvi Sahni, Ari M Melnick, Giorgio Inghirami, Leandro Cerchietti, John P. Leonard, Peter Martin

Blood (2024) 144 (Supplement 1): 1693.

https://doi.org/10.1182/blood-2024-206606

Published: 2024

Journal Articles

Integrated Omics to Dissect the Landscape in Chemosensitive and Refractory Extranodal Natural-Killer T-Cell Lymphoma (ENKTCL): A Global Study of the PETAL (PEripheral T-Cell Lymphoma) Consortium

Blood (2024) 144 (Supplement 1): 6207.

https://doi.org/10.1182/blood-2024-208838

Published: 2024

Journal Articles

MRD-Driven Time-Limited Therapy of Acalabrutinib and Lenalidomide Plus Rituximab (ALR) or Obinutuzumab (ALO) in Patients with Treatment-Naïve Mantle Cell Lymphoma: Phase 2 Trial Outcomes with MRD and cfDNA Analyses

Jia Ruan, David A. Bond, Bijal D Shah, John N. Allan, Sarah C. Rutherford, Caitlin Gribbin, Zhengming Chen, Brittany Hobbie, Melinda Harbhajan, Tejasvi Sahni, Wayne Tam, Bhavneet Bhinder, Michael Sigouros, Giorgio Inghirami, Selina Chen-Kiang, Olivier Elemento, Kami J. Maddocks, John P. Leonard, Peter Martin

Blood (2024) 144 (Supplement 1): 746.

https://doi.org/10.1182/blood-2024-204495

Published: 2024

Journal Articles

Disrupting IL10 Signaling Overcomes Compound Copy Number Variation-Driven Clinical Resistance to CDK4/6 and BTK Inhibition in Mantle Cell Lymphoma

Maurizio Di Liberto, Yang Hu, Xiangao Huang, Giorgio Inghirami, Kevin Wang, Christina Y. Lee, Kami J. Maddocks, Kristie A. Blum, Jia Ruan, John P. Leonard, Nancy L. Bartlett, Peter Martin, Olivier Elemento, Selina Chen-Kiang

Blood (2024) 144 (Supplement 1): 831.

https://doi.org/10.1182/blood-2024-209415

Published: 2024

Journal Articles

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Blood (2024) 144 (Supplement 1): 229.

https://doi.org/10.1182/blood-2024-204606

Published: 2024

Journal Articles

Genetic Subclones Reveal Phenotypic Heterogeneity in Diffuse Large B-Cell Lymphoma

Boya Wang, George W. Wright, Julius C. Enssle, Yandan Yang, Da Wei Huang, Xin Yu, Arvin E Ruiz, James D. Phelan, Arthur L Shaffer, III, Thomas Oellerich, Giorgio Inghirami, Louis M. Staudt

Blood (2024) 144 (Supplement 1): 451.

https://doi.org/10.1182/blood-2024-204201

Published: 2024

Journal Articles

Machine Learning-Based Approach to Improve Classification and Diagnostics of Peripheral T-Cell Lymphomas

Anastasia Sobol, Stepan Kuznetsov, Anton Kremlev, Giorgio Inghirami, Nathan Fowler, Nikita Kotlov, Anastasia Nikitina

Blood (2024) 144 (Supplement 1): 1593.

https://doi.org/10.1182/blood-2024-201683

Published: 2024

Journal Articles

New insights into the biology of T-cell lymphomas

Javeed Iqbal, Giorgio Inghirami, Wing C. Chan

Blood (2024) 144 (18): 1873–1886.

https://doi.org/10.1182/blood.2023021787

Published: 2024

Includes: Supplemental data

Journal Articles

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

Blood (2024) 144 (5): 525–540.

https://doi.org/10.1182/blood.2024024251

Published: 2024

Includes: Supplemental data

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CDK7 enables adaptive gene transcription required by stromal cells to support distinct T-cell lymphoma phenotypes and represents a novel microenvironment-directed therapeutic target

Adenosine pathway as a therapeutic target in diffuse large B cell lymphoma

Gene-regulatory axes of diffuse large B-cell lymphoma subtypes

A phase 1b trial of the EZH2 inhibitor tazemetostat combined with CAR T cell therapy in B cell lymphomas

Primary central nervous system lymphoma reveals a pro-tumoral brain-specific myeloid landscape.

Sasp-driven immune evasion defines a novel African ancestry-associated DLBCL subtype with distinctive molecular and immune vulnerabilities

Humanized PDX models reveal Lymphoma–Host interactions and enhanced T-cell therapies via epigenetic modulation

Real-world impact of differences in the WHO and ICC classifications of non-Hodgkin lymphoma: a LEO cohort study analysis

Biological and Prognostic Subgroups of Plasmablastic Lymphoma Defined By EBV Status and MYC Rearrangement- an L.L.M.P.P. Study

An Llmpp Study: Genomic Characterization of Novel PTCL- Biological Subtypes Reveal Distinctive Therapeutic Vulnerabilities

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Subsequent Treatment and Clinical Outcome Following Induction Therapy on a Phase II Study of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL)

Integrated Omics to Dissect the Landscape in Chemosensitive and Refractory Extranodal Natural-Killer T-Cell Lymphoma (ENKTCL): A Global Study of the PETAL (PEripheral T-Cell Lymphoma) Consortium

MRD-Driven Time-Limited Therapy of Acalabrutinib and Lenalidomide Plus Rituximab (ALR) or Obinutuzumab (ALO) in Patients with Treatment-Naïve Mantle Cell Lymphoma: Phase 2 Trial Outcomes with MRD and cfDNA Analyses

Disrupting IL10 Signaling Overcomes Compound Copy Number Variation-Driven Clinical Resistance to CDK4/6 and BTK Inhibition in Mantle Cell Lymphoma

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Genetic Subclones Reveal Phenotypic Heterogeneity in Diffuse Large B-Cell Lymphoma

Machine Learning-Based Approach to Improve Classification and Diagnostics of Peripheral T-Cell Lymphomas

New insights into the biology of T-cell lymphomas

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

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American Society of Hematology

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