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Larry Kwak
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Journal Articles

BAFFR-CAR T cells (PMB-CT01) demonstrate durable responses and manageable toxicities in relapsed/refractory B-cell lymphomas with prior CD19-directed therapy failure or CD19-negative disease

Free
Elizabeth Budde, Marissa Del Real, John Baird, Lu Chen, Joo Song, Xiuli Wang, Swetha Thiruvengadam, Marie Hu, Alan Macias, Emanuela Marcucci, Soungchul Cha, Zhenyuan Dong, Teresa Kim, Baishakhi Barva, Sandrine Puverel, Qing Liu-Michael, Hazel (Ting-Ying) Cheng, Stephen Forman, Larry Kwak
Journal: Blood
Blood (2025) 146 (Supplement 1): 268.
https://doi.org/10.1182/blood-2025-268
Published: 2025
Journal Articles

High rates of financial toxicity and time toxicity in patients receiving chimeric antigen receptor therapy and bispecific antibodies for lymphoma and multiple myeloma: A prospective mixed methods study.

Free
Swetha Thiruvengadam, Nishita Matangi, Murali Janakiram, Annie Xiao, Mark Ponce, Brian Lee, Stacy Pak, Benjamin Martini, Diamond Ward, Ryan Chiechi, Diane Smith, John Baird, Azra Borogovac, Elizabeth Budde, Alexey Danilov, Alex Herrera, Myo Htut, James Godfrey, Scott Goldsmith, Avyakta Kallam, Amrita Krishnan, Larry Kwak, Sarah Lee, Matthew Mei, Nitya Nathwani, Michael Rosenzweig, Firoozeh Sahebi, Tycel Phillips, Geoffrey Shouse, Tanya Siddiqi, Brian Sworder, Kimlin Ashing, Nikhil Thiruvengadam, Steven Rosen
Journal: Blood
Blood (2025) 146 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2025-6364
Published: 2025
Journal Articles

Phase II investigator-initiated trial of epcoritamab-lenalidomide in treatment naïve follicular lymphoma

Free
Swetha Thiruvengadam, Lu Chen, Vi Lam, Xiaofan Zhao, Avyakta Kallam, John Baird, Azra Borogovac, James Godfrey, Alex Herrera, Tycel Phillips, Abbey Fueger, Lara Rodriguez, Katie Romero, Neer Patel, Eunice Canche, Ashly Grafton, Dina Hassan, Diane Smith, Larry Kwak, Steven Rosen, Zheng Xia, Alexey Danilov
Journal: Blood
Blood (2025) 146 (Supplement 1): 5373.
https://doi.org/10.1182/blood-2025-5373
Published: 2025
Journal Articles

BAFFR-CAR T cells (PMB-CT01) show promising safety and anti-leukemia efficacy in relapsed/refractory B-cell ALL patients after CD19-targeted therapy failure, including CD19-negative disease

Free
Ibrahim Aldoss, Xiuli Wang, Lu Chen, Joo Song, Karamjeet Sandhu, Alan Macias, Neguine Sanani, Baishakhi Barva, Min Guan, Ruby Espinosa, Sandrine Puverel, Qing Liu-Michael, Hazel (Ting-Ying) Cheng, Guido Marcucci, Elizabeth Budde, Larry Kwak, Stephen Forman
Journal: Blood
Blood (2025) 146 (Supplement 1): 813.
https://doi.org/10.1182/blood-2025-813
Published: 2025
Journal Articles

Humanized PDX models reveal Lymphoma–Host interactions and enhanced T-cell therapies via epigenetic modulation

Free
Giovanni Medico, Giorgia Zanetti, Giorgio Bertolazzi, Francesco Vallania, Paul Zumbo, Maider Amiama, Doron Betel, Maria Cacciapuoti, Abigail Taylor, Clarisse Kayembe, Sanjay Patel, Jennifer Ziello, Arvin Ruiz, Jason Weirather, Gulpreet Kaur, Luca Cappelli, Luca Paruzzo, Marco Ruella, Zhenyuan Dong, Larry Kwak, Nicolás Di Siervi, María Revuelta, Claudio Tripodo, Leandro Cerchietti, Giorgio Inghirami
Journal: Blood
Blood (2025) 146 (Supplement 1): 350.
https://doi.org/10.1182/blood-2025-350
Published: 2025
Journal Articles

Pembrolizumab plus vorinostat induces responses in patients with Hodgkin lymphoma refractory to prior PD-1 blockade

Free
Clinical Trials & Observations
Matthew Mei, Lu Chen, James Godfrey, Joo Song, Colt Egelston, Sandrine Puverel, L. Elizabeth Budde, Saro Armenian, Liana Nikolaenko, Mary Nwangwu, Weihua Guo, Lei Gao, Peter Lee, Robert Chen, Shari Daniels, Neena Kennedy, Lacolle Peters, Jasmine Zain, Steven Rosen, Stephen Forman, Leslie Popplewell, Larry Kwak, Alex F. Herrera
Journal: Blood
Blood (2023) 142 (16): 1359–1370.
https://doi.org/10.1182/blood.2023020485
Published: 2023
Includes: Supplemental data
Journal Articles

Response-adapted anti-PD-1–based salvage therapy for Hodgkin lymphoma with nivolumab alone or in combination with ICE

Free
Clinical Trials & Observations
Matthew G. Mei, Hun Ju Lee, Joycelynne M. Palmer, Robert Chen, Ni-Chun Tsai, Lu Chen, Kathryn McBride, D. Lynne Smith, Ivana Melgar, Joo Y. Song, Kimberley-Jane Bonjoc, Saro Armenian, Mary Nwangwu, Peter P. Lee, Jasmine Zain, Liana Nikolaenko, Leslie Popplewell, Auayporn Nademanee, Ammar Chaudhry, Steven Rosen, Larry Kwak, Stephen J. Forman, Alex F. Herrera
Journal: Blood
Blood (2022) 139 (25): 3605–3616.
https://doi.org/10.1182/blood.2022015423
Published: 2022
Includes: Supplemental data
Journal Articles

Quantitative Baseline Circulating Tumor DNA Levels Correlate with GM-CSF Response to Idiotype Vaccine in Untreated Mantle Cell Lymphoma

Free
Mark Roschewski, MD, Kieron Dunleavy, MD, Sattva S. Neelapu, MD, Stefania Pittaluga, MD PhD, Christopher Joseph Melani, MD, Elaine S. Jaffe, MD, Margaret Shovlin, RN, Beryl Crossley, BS, Katie Kong, BS, Allison Jacob, MD, Larry Kwak, Wyndham H. Wilson, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2943.
https://doi.org/10.1182/blood.V128.22.2943.2943
Published: 2016
Journal Articles

Randomized Phase II Trial of Combination Idiotype Vaccine and Anti-CD3/Anti-CD28 Costimulated Autologous T Cells in Patients with Multiple Myeloma Post-Autotransplantation

Free
Muzaffar H. Qazilbash, MD, Edward A Stadtmauer, MD, Veera Baladandayuthapani, PhD, Heather Lin, M.S., Beryl M. Tross, Medhavi Honhar, MBBS, Soung-Chul Cha, PhD, Kunhwa Kim, MD, Sheetal S Rao, PhD, Michael Popescu, MD, Nina Shah, MD, Qaiser Bashir, MD, Krina Patel, MD, Elizabeth J. Shpall, MD, Donna M. Weber, MD, Sheeba K. Thomas, MD, Jatin J. Shah, MD, Robert Z. Orlowski, PhD, MD, Naseem DS Kerr, MPH, Alfred L. Garfall, MD, Adam D. Cohen, MD, Karen Dengel, BSN, RN, Carl H June, MD, Richard E. Champlin, MD, Larry Kwak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4548.
https://doi.org/10.1182/blood.V128.22.4548.4548
Published: 2016
Journal Articles

Pharmacokinetic and Safety of CT-P10, a Biosimilar Candidate to the Rituximab Reference Product, in Patients with Newly Diagnosed Advanced Stage Follicular Lymphoma (AFL)

Free
Bertrand Coiffier, Juan-Manuel Sancho, Wojciech Jurczak, Jin Seok Kim, Raj V Nagarkar, Edvard Zhavrid, Jose Angel Hernandez Rivas, Aliaksandr Prokharau, Mamia Zodelava, Dzhelil Osmanov, Michinori Ogura, Christian Buske, Larry Kwak, Sang Joon Lee, Sung Young Lee, Yun Ju Bae, Won Seog Kim
Journal: Blood
Blood (2016) 128 (22): 1807.
https://doi.org/10.1182/blood.V128.22.1807.1807
Published: 2016
Journal Articles

Osteoblastic niche supports the growth of quiescent multiple myeloma cells

Free
Brief Report
Zheng Chen, Robert Z. Orlowski, Michael Wang, Larry Kwak, Nami McCarty
Journal: Blood
Blood (2014) 123 (14): 2204–2208.
https://doi.org/10.1182/blood-2013-07-517136
Published: 2014
Includes: Supplemental data
Journal Articles

Non-Stereotypic Follicular Lymphoma B-Cell Receptors Recognize Vimentin as a Shared Autoantigen

Free
Soung-Chul Cha, Hong Qin, Shivichakravarthy Kannan, Seema Rawal, PhD, Weiguo Wu, Juliana Ong, Jinsong Wei, Benjamin Kwak, Sang Kim, Michael Popescu, Daniel Paick, Richard Davis, Larry Kwak, Sattva S. Neelapu
Journal: Blood
Blood (2010) 116 (21): 139.
https://doi.org/10.1182/blood.V116.21.139.139
Published: 2010
Journal Articles

Outcomes of Nodular Lymphocyte Predominant Hodgkin's Lymphoma (NLPHL) Patients Treated with R-CHOP.

Free
Michelle A. Fanale, MD, Chao-Ming Lai, APN, Peter McLaughlin, MD, Jorge Romaguera, MD, Luis Fayad, MD, Fredrick Hagemeister, MD, Felipe Samaniego, MD, MPH, Maria Alma Rodriguez, MD, Sattva S. Neelapu, Jatin J Shah, MD, Larry Kwak, Wenli Dong, Valerie Reed, MD, Bouthaina S. Dabaja, MD, Uday Popat, MD, Anas Younes, MD
Journal: Blood
Blood (2010) 116 (21): 2812.
https://doi.org/10.1182/blood.V116.21.2812.2812
Published: 2010
Journal Articles

Role of Microenvironment In Mantle Cell Lymphoma: IL-6 as An Important Survival Factor for Tumor Cells

Free
Liang Zhang, MD, PhD, Jing Yang, PhD, Jianfei Qian, PhD, Sattva Neelapu, MD, Larry Kwak, MD, PhD, Michael Wang, MD, Qing Yi, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3929.
https://doi.org/10.1182/blood.V116.21.3929.3929
Published: 2010
Journal Articles

Randomized, Double-Blind, Placebo-Controlled, Dose and Schedule-Finding Study of AMG 531 In Chemotherapy-Induced Thrombocytopenia (CIT): Results of a Phase I/II Study.

Free
Saroj Vadhan-Raj, MD, Fredrick Hagemeister, Luis E. Fayad, MD, Xiao Zhou, MD, PHD, Shana Sherril ORoark, APN, Kandice Ames, RN, Maria Alma Rodriguez, MD, Michelle A. Fanale, MD, Barbara Pro, MD, Marcella M. Johnson, MS, Peter McLaughlin, MD, Carlos E. Bueso-Ramos, Anas Younes, MD, Larry Kwak, MD, PHD, Jorge Enrique Romaguera
Journal: Blood
Blood (2010) 116 (21): 1544.
https://doi.org/10.1182/blood.V116.21.1544.1544
Published: 2010
Journal Articles

Novel PI3K Inhibitor Compound A Induces Myeloma Cell Apoptosis and Shows Synergistic Cytotoxicity with Dexamethasone In Multiple Myeloma

Free
Yuhuan Zheng, PhD, Jing Yang, PhD, Liang Zhang, MD, PhD, Jianfei Qian, PhD, Jairo Matthews, Michael Wang, MD., Larry Kwak, Qing Yi, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4080.
https://doi.org/10.1182/blood.V116.21.4080.4080
Published: 2010
Journal Articles

Vaccination with IgM but Not IgG Idiotype Prolongs Remission Duration In Follicular Lymphoma Patients

Free
Stephen J. Schuster, Carlos F. Santos, Sattva S. Neelapu, Donald A. Berry, Mihaela A. Popa, Amy M. McCord, Elise A. Chong, Larry Kwak
Journal: Blood
Blood (2010) 116 (21): 429.
https://doi.org/10.1182/blood.V116.21.429.429
Published: 2010
Journal Articles

A Biologic Combination of Lenalidomide and Rituximab for Front-Line Therapy of Indolent B-Cell Non-Hodgkin's Lymphoma.

Free
Nathan Fowler, M.D., Peter McLaughlin, M.D., Fredrick B. Hagemeister, M.D., Larry Kwak, M.D., Ph.D., Michelle Fanale, M.D., Sattva Neelapu, M.D., Luis Fayad, M.D., Barbara Pro, M.D., Crystal Sergent, RN, MSN, Shana R. S. White, B.S., Felipe Samaniego, M.D.
Journal: Blood
Blood (2009) 114 (22): 1714.
https://doi.org/10.1182/blood.V114.22.1714.1714
Published: 2009
Journal Articles

Randomized Clinical Trial of Rasburicase Administered as a Standard Fixed Five Days Dosing Vs a Single Dose Followed by as Needed Dosing in Adult Patients with Hematologic Malignancies at Risk for Developing Tumor Lysis Syndrome.

Free
Saroj Vadhan-Raj, MD, Luis Fayad, MD, Michelle Fanale, M.D., Barbara Pro, Alma Rodriguez, Frederick Hagemeister, Kandice Ames, RN, Carlos E. Bueso-Ramos, MD, Xiao Zhou, MD, PHD, Peter McLaughlin, Nathan Fowler, Jatin Shah, MD, Felipe Samaniego, MD, Anas Younes, MD, Larry Kwak, MD, PHD, Jorge Romaguera, MD
Journal: Blood
Blood (2009) 114 (22): 105.
https://doi.org/10.1182/blood.V114.22.105.105
Published: 2009
Journal Articles

A Phase I/II Study of Lenalidomide in Combination with Rituximab in Relapsed/Refractory Mantle Cell Lymphoma.

Free
Luhua Wang, MD, Luis Fayad, MD, Fredrick B. Hagemeister, MD, Sattva Neelapu, MD, Felipe Samaniego, MD, Peter McLaughlin, MD, Barry Samuels, MD, Qing Yi, MD, PhD, Barbara Pro, MD, Michelle Fanale, M.D., Jatin Shah, MD, Anas Younes, MD, Neda Bell, Robert Knight, MD, Jerome B. Zeldis, MD, PhD, Fernando Cabanillas, MD, Larry Kwak, MD, PHD, Jorge Romaguera, MD
Journal: Blood
Blood (2009) 114 (22): 2719.
https://doi.org/10.1182/blood.V114.22.2719.2719
Published: 2009