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Journal Articles

Genomic and transcriptomic landscape of extranodal marginal zone lymphoma

Free
Izidore S. Lossos, Leo Biral, Devang Thakkar, Kikkeri N Naresh, Sarah Ondrejka, Eric Hsi, Mina Xu, Jean Koff, David Jaye, Peter Nørgaard, Marie Fredslund Breinholt, Rebecca Leeman-Neill, Jennifer Shingleton, Lanie Happ, Cassandra Love, Emily F. Mason, Abner Louissaint, Choon Kiat Ong, Chee Leong Cheng, Raju Pillai, Mette Pedersen, C. Cameron Yin, Rex Au-Yeung, Marja-Liisa Karjalainen-Lindsberg, Amy Chadburn, Matthew McKinney, Payal Sojitra, Andrew Evans, Magdalena Czader, Yan Jiong, Sandeep Dave, Jennifer Chapman
Journal: Blood
Blood (2025) 146 (Supplement 1): 1761.
https://doi.org/10.1182/blood-2025-1761
Published: 2025
Journal Articles

Bystander activation drives CD8+ t cells response in lymphoma-associated hemophagocytic lymphohistiocytosis

Free
Wendy Lee, Jing Quan Lim, Ser Mei Koh, Shanshan Wu-Howland, Rachel R.S. Ang, Rong En Tay, Alicia Tay, Jack Wee Lim, Kim Peng Tan, Kerry Lim, Soon Thye Lim, Choon Kiat Ong, Olaf Rötzschke
Journal: Blood
Blood (2025) 146 (Supplement 1): 4756.
https://doi.org/10.1182/blood-2025-4756
Published: 2025
Journal Articles

Novel immune gene expression signature risk-stratifies Mantle Cell Lymphoma outcomes independent of TP53 status

Free
Jean Koff, Veronica Russell, Rachel Kositsky, David Jaye, Michael Churnetski, Katelin Baird, Colin O'Leary, Christopher Flowers, Sirpa Leppä, Shaoying Li, Jessie Xu, Mette Pedersen, Anne Ortved Gang, Kikkeri N Naresh, Rex Au-Yeung, Jennifer Chapman, Amy Chadburn, Izidore S. Lossos, Sarah Ondrejka, Abner Louissaint, Eric Tse, Cassandra Love, Devang Thakkar, Clayton Parker, Choon Kiat Ong, Andrew Evans, Emily F. Mason, Yan Jiong, Magdalena Czader, Andrew Evens, Dina Soliman, Yuri Fedoriw, Sandeep Dave, Jonathon Cohen
Journal: Blood
Blood (2025) 146 (Supplement 1): 352.
https://doi.org/10.1182/blood-2025-352
Published: 2025
Journal Articles

Efficacy of combined CD38 and PD-1 inhibition with isatuximab and cemiplimab for relapsed/refractory NK/T-cell lymphoma

Available to Purchase
Clinical Trials & Observations
Seok Jin Kim, Jing Quan Lim, Sang Eun Yoon, Deok-Hwan Yang, Ji Hyun Lee, Sung Yong Oh, Yoon Seok Choi, Seong Hyun Jeong, Min Kyoung Kim, Sung Nam Lim, Junhun Cho, Bon Park, Kyung Ju Ryu, Seunghyun Choi, Yoon Park, Kerry May Huifen Lim, Nur Ayuni Binte Muhammad Taib, Choon Kiat Ong, Soon Thye Lim, Won Seog Kim
Journal: Blood
Blood (2025) 146 (2): 155–166.
https://doi.org/10.1182/blood.2024027109
Published: 2025
Includes: Supplemental data
Journal Articles

Frequent Copy Gains of Viral LMP-1 Confers Radiosensitivity in Natural-Killer/T Cell Lymphoma

Free
Jing Quan Lim, Dachuan Huang, Kelila Xin Ye Chai, Phyu The, Kerry May Huifen Lim, Wendy Lee, Liang Wei Wang, Nur Ayuni Muhammad Taib, Beng Hooi Phang, Wee-Joo Chng, Olaf Rötzschke, Jason Yongsheng Chan, Soon Thye Lim, Jin-Xin BEI, Siok-Bian Ng, Choon Kiat Ong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2963.
https://doi.org/10.1182/blood-2024-192976
Published: 2024
Journal Articles

Functional Consequences of Chromosomal Alterations in Angioimmunoblastic T-Cell Lymphoma

Free
Huang Dachuan, Jason Yongsheng Chan, Choon Kiat Ong, Jing Quan Lim
Journal: Blood
Blood (2024) 144 (Supplement 1): 6180.
https://doi.org/10.1182/blood-2024-193215
Published: 2024
Journal Articles

Therapeutic Repurposing of Brincidofovir in Non-Hodgkin Lymphoma - Potential Synergy with Immune Checkpoint Blockade

Free
Jason Yongsheng Chan, Elizabeth Chun Yong Lee, Kelila Xin Ye Chai, Boon Yee Lim, Zhimei Li, Jing Yi Lee, Bavani Kannan, Tun Kiat Ko, Jessica Sook-Ting Kok, Kah Suan Lim, Nur Ayuni Muhammad Taib, Dachuan Huang, Jing Quan Lim, Masatoshi Hazama, Koji Fukushima, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2024) 144 (Supplement 1): 4172.
https://doi.org/10.1182/blood-2024-202761
Published: 2024
Journal Articles

Single-cell landscape of idiopathic multicentric Castleman disease in identical twins

Free
Brief Report
Jason Yongsheng Chan, Jui Wan Loh, Jing Quan Lim, Herty Liany, Elizabeth Chun Yong Lee, Jing Yi Lee, Bavani Kannan, Boon Yee Lim, Zexi Guo, Kerry Lim, Jeslin Chian Hung Ha, Cedric Chuan-Young Ng, Tun Kiat Ko, Dachuan Huang, Dominique Yuan Bin Seow, Chee Leong Cheng, Sock Hoai Chan, Joanne Ngeow, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2024) 143 (18): 1837–1844.
https://doi.org/10.1182/blood.2023021992
Published: 2024
Includes: Supplemental data
Journal Articles

Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression

Free
Ilja Kalashnikov, Veronica Russell, Panu Kovanen, Johannes Dunkel, Marja-Liisa Karjalainen-Lindsberg, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Tanu Goyal, Eric D. Hsi, Mette Ølgod Pedersen, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina Xu, Nathan Paulson, Jean L. Koff, Andrew G Evans, Yasodha Natkunam, Ridas Juskevicius, Abner Louissaint, Elizabeth Thacker, Tushar Dave, Cassandra L. Love, Chad M McCall, Choon Kiat Ong, Michael Churnetski, Haley Martin, Jennifer R. Chapman-Fredricks, Javeed Iqbal, Amy Chadburn, Payal Sojitra, Amir Behdad, William Choi, Jie Xu, Emily F. Ferguson Mason, Kikkeri N Naresh, Yuri D. Fedoriw, Dina Sameh Soliman, Sandeep Dave, Sirpa Leppä
Journal: Blood
Blood (2023) 142 (Supplement 1): 176.
https://doi.org/10.1182/blood-2023-182294
Published: 2023
Journal Articles

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma

Free
Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Ab Rauf Shah, Waseem Gul Lone, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla Heavican-Foral, Jeffrey Cannatella, Catalina Amador, Aiza Arif, Lynette Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming-Qing Du, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodak, Sigve Nakken, Jan Delabie, David M. Weinstock, Stefano A. Pileri, Antonella Laginestra, Kyeongjin Kim, Utpal Pajvani, Julie M. Vose, Dennis D Weisenburger, Sandeep Dave, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2023) 142 (Supplement 1): 2993.
https://doi.org/10.1182/blood-2023-186530
Published: 2023
Journal Articles

Nodular Lymphocyte Predominant Hodgkin Lymphoma with Splenic Involvement Is Characterized By Inflamed Tumor Microenvironment, High Expression of Checkpoint Molecule Gene-Signature and Adverse Outcome

Free
Ilja Kalashnikov, Marja-Liisa Karjalainen-Lindsberg, Panu Kovanen, Johannes Dunkel, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Eric D. Hsi, Andrew G Evans, Mette Ø Pedersen, Peter H. Norgaard, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina L Xu, Nathan Paulson, Ridas Juskevicius, Yasodha Natkunam, Abner Louissaint, Jr., Haley Martin, Elizabeth Thacker, Cassandra Love, Shari Tian, Choon Kiat Ong, Chee Leong Cheng, Chad M. McCall, Jean L. Koff, Sheren F. Younes, Mary Ann Arildsen, Jennifer R Chapman-Fredricks, Catalina Amador, Yuri Fedoriw, Carla Casulo, Amy Chadburn, Payal Sojitra, Amir Behdad, Eric Tse, Kikkeri N Naresh, C. Cameron Yin, Rashmi S. Goswami, Sandeep Dave, Sirpa Leppa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3559–3561.
https://doi.org/10.1182/blood-2022-169476
Published: 2022
Journal Articles

Mutations of ATM Confer a Risk of Inferior Survival in Patients with TP53- wild Type Mantle Cell Lymphoma

Free
Jean L. Koff, Rachel Kositsky, David L Jaye, Michael C. Churnetski, Katelin Baird, Colin B. O'Leary, Christopher R. Flowers, Sirpa Leppa, Marja-Liisa Karjalainen-Lindsberg, Shaoying Li, Jie Xu, Mette Ø Pedersen, Anne Ortved Gang, Kikkeri N Naresh, Rebecca J Leeman-Neill, Kwok Him Rex Au Yeung, Hina Naushad Qureishi, Javeed Iqbal, Jennifer R Chapman-Fredricks, Chad M. McCall, Michael Crump, Amy Chadburn, Erin C. Mulvey, Izidore S. Lossos, Sandra L. Ondrejka, Eric D. Hsi, Abner Louissaint, Jr., Haley Martin, Eric Tse, Cassandra Love, Tushar Dave, Clay Parker, Choon Kiat Ong, Andrew G Evans, Amir Behdad, Lixin Yang, Nishitha Reddy, Mary Ann Arildsen, Ridas Juskevicius, Jiong Yan, Magdalena Czader, Andrew M. Evens, Dina Sameh Soliman, Yuri Fedoriw, Sandeep S. Dave, Jonathon B. Cohen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3500–3503.
https://doi.org/10.1182/blood-2022-168002
Published: 2022
Journal Articles

A Non-Coding Variant in LOC105371512 Confers Susceptibility to Bleomycin-Induced Lung Injury

Free
Joanne Lee, Hossein Tabatabaeian, Michelle Limei Poon, Nagavalli Somasundaram, Liu Xin, Yi Ching Yuen, Chia Meng Teoh, Benedict Yan, Esther Hian Li Chan, Yen Lin Chee, Sanjay De Mel, Bin Zhang, Xiao Hong Chew, Tiffany Tang, Chiea Chuen Khor, Joanne Yuen Yie Ngeow, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, E Shyong Tai, Kee Yuan Ngiam, Soo Chin Lee, Boon Cher Goh, Anand Devaprasath D. Jeyasekharan, Yvonne Tay, Folefac Aminkeng
Journal: Blood
Blood (2022) 140 (Supplement 1): 4542–4544.
https://doi.org/10.1182/blood-2022-169416
Published: 2022
Journal Articles

Therapeutic Repurposing of Brincidofovir in Natural Killer/T-Cell Lymphoma Reveals Potent Induction of Replication Stress, Sting Pathway Activation and Immunogenic Cell Death

Free
Jason Yongsheng Chan, Elizabeth Chun Yong Lee, Kelila Xin Ye Chai, Jing Yi Lee, Bavani Kannan, Boon Yee Lim, Jessica Sook-Ting Kok, Zhimei Li, Jui Wan Loh, Tun Kiat Ko, Kah Suan Lim, Cedric Chuan-Young Ng, Kerry Lim, Dachuan Huang, Jing Quan Lim, Masatoshi Hazama, Koji Fukushima, Bin Tean Teh, Soon Thye Lim, Choon Kiat Ong
Journal: Blood
Blood (2022) 140 (Supplement 1): 2256–2257.
https://doi.org/10.1182/blood-2022-163243
Published: 2022
Journal Articles

Extranodal Marginal Zone Lymphomas Show Recurrent Mutations in DNA Repair Genes, Cancer-Associated Proliferative Signaling and NOTCH1 Signaling Pathways, Regardless of Anatomic Site

Free
Jennifer R Chapman-Fredricks, Devang Thakkar, Juan Pablo Alderuccio, Kikkeri N Naresh, Sarah L. Ondrejka, Eric D. Hsi, Mina L Xu, Nathan Paulson, Jean L. Koff, David L Jaye, Jonathon B. Cohen, Anne Ortved Gang, Rebecca J Leeman-Neill, Tushar Dave, Lanie Happ, Cassandra Love, Sasan Zandi, Hina Naushad, Emily F Mason, Abner Louissaint, Jr., Haley Martin, Choon Kiat Ong, Raju Pillai, Mette Ø Pedersen, C. Cameron Yin, William Choi, Rex Kwok Him Au-Yeung, Marja-Liisa Karjalainen-Lindsberg, Amy Chadburn, Vincent Sarno, Matthew McKinney, Payal Sojitra, Andrew G Evans, Amir Behdad, Carlos Galvez, Chee Leong Cheng, Magdalena Czader, Jiong Yan, Sandeep S. Dave, Izidore S. Lossos
Journal: Blood
Blood (2022) 140 (Supplement 1): 6378–6380.
https://doi.org/10.1182/blood-2022-165616
Published: 2022
Journal Articles

DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T cells in PTCL-NOS

Free
Tyler A. Herek, Alyssa Bouska, Waseem Lone, Sunandini Sharma, Catalina Amador, Tayla B. Heavican, Yuping Li, Qi Wei, Dylan Jochum, Timothy C. Greiner, Lynette Smith, Stefano Pileri, Andrew L. Feldman, Andreas Rosenwald, German Ott, Soon Thye Lim, Choon Kiat Ong, Joo Song, Elaine S. Jaffe, Gang Greg Wang, Louis Staudt, Lisa M. Rimsza, Julie Vose, Francesco d’Amore, Dennis D. Weisenburger, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2022) 140 (11): 1278–1290.
https://doi.org/10.1182/blood.2021015019
Published: 2022
Includes: Supplemental data
Journal Articles

A Clinical Prognostic Index for Angioimmunoblastic T Cell Lymphoma in an Asian Multi-Centre Study

Free
Esther Chang, Valerie Shiwen Yang, Shin Yeu Ong, Hilda Kang, Ya Hwee Tan, Jianbang Chiang, Eileen Yi Ling Poon, Nagavalli Somasundaram, Mohamad Farid, Tiffany Tang, Miriam Tao, Lay Poh Khoo, Choon Kiat Ong, Soon Thye Lim, Jason Yongsheng Chan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2453.
https://doi.org/10.1182/blood-2021-147679
Published: 2021
Journal Articles

The Atlas of Blood Cancer Genomes (ABCG) Project: A Comprehensive Molecular Characterization of Leukemias and Lymphomas

Free
Cassandra Love, Raju Pillai, Sarah L. Ondrejka, Govind Bhagat, Amy Chadburn, Matthew McKinney, Jean L. Koff, Dina Sameh Soliman, Magdalena Czader, Abner Louissaint, Jr., Shaoying Li, Choon Kiat Ong, Amir Behdad, Andrew M. Evens, Yasodha Natkunam, Peter H. Norgaard, Sirpa Leppa, Eric Tse, Jennifer R Chapman, Catalina Amador, Yuri Fedoriw, Agata M. Bogusz, Andrew G Evans, Rashmi S. Goswami, Ridas Juskevicius, Mina L. Xu, Kikkeri N Naresh, Barbara Xiong, Adam Snowden, Anabel Thurman, Eileen Smith, Tushar Dave, Rachel Kositsky, Devang Thakkar, Veronica Russell, Caroline J Roth, Sandeep Dave
Journal: Blood
Blood (2021) 138 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2021-151346
Published: 2021
Journal Articles

Genomic and Transcriptional Characterization of Primary Mediastinal Large B Cell Lymphoma

Free
Rebecca J Leeman-Neill, Devang Thakkar, Sarah L. Ondrejka, Eric D. Hsi, Amy Chadburn, Mateo Mejia Saldarriaga, Sarah C. Rutherford, Chad M. McCall, Tareq Aljurf, Matthew McKinney, Jean L. Koff, David L Jaye, Jonathon B. Cohen, Dina Sameh Soliman, Abner Louissaint, Jr., Choon Kiat Ong, Chee Leong Cheng, Lianne Lee, Amir Behdad, Peter H. Norgaard, Andrew G Evans, Rashmi S. Goswami, Ridas Juskevicius, Mary Ann Arildsen, Kikkeri N Naresh, Caroline J Roth, Sandeep S. Dave, Govind Bhagat
Journal: Blood
Blood (2021) 138 (Supplement 1): 2398.
https://doi.org/10.1182/blood-2021-149745
Published: 2021
Journal Articles

ALK-Negative Anaplastic Large Cell Lymphomas Encompass Distinct Subgroups Including an ALK-Positive-like Subgroup with Favorable Prognosis

Free
Kwok Him Rex Au Yeung, Veronica Russell, William Choi, Alice Wong, Lawrence Tsui, Yu Yan Carmen Lee, Jamilla Li, Harinder Gill, Ho-Wan Ip, Yok Lam Kwong, Tushar Dave, Sarah L. Ondrejka, Govind Bhagat, Amy Chadburn, Sarah C. Rutherford, Jean L. Koff, David L Jaye, Magdalena Czader, Abner Louissaint, Jr., Shaoying Li, Jie Xu, C. Cameron Yin, Choon Kiat Ong, Chee Leong Cheng, Amir Behdad, Andrew M. Evens, Peter H. Norgaard, Anne Ortved Gang, Sirpa Leppa, Marja-Liisa Karjalainen-Lindsberg, Jennifer R Chapman, Catalina Amador, Javeed Iqbal, Yuri Fedoriw, Agata M. Bogusz, Andrew G Evans, Ridas Juskevicius, Eric D. Hsi, Kikkeri N Naresh, Sandeep S. Dave, Eric Tse
Journal: Blood
Blood (2021) 138 (Supplement 1): 2403.
https://doi.org/10.1182/blood-2021-148807
Published: 2021