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Journal Articles

ST2 promotes leukemia transformation by reshaping the immune landscape in Acute Myeloid Leukemia

Yu-Hsuan Fu, Man Li, Ying-Chieh Chen, Lianjun Zhang, Wancheng Guo, David Frankhouser, Denis O'Meally, Jihyun Irizarry, Jennifer Rangel Ambriz, Ziang Chen, Bin Zhang, Sergio Branciamore, Guido Marcucci, Russell Rockne, Ya-Huei Kuo

Blood (2025) 146 (Supplement 1): 1459.

https://doi.org/10.1182/blood-2025-1459

Published: 2025

Journal Articles

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Blood (2025) 146 (Supplement 1): 212.

https://doi.org/10.1182/blood-2025-212

Published: 2025

Journal Articles

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

Blood (2025) 146 (Supplement 1): 211.

https://doi.org/10.1182/blood-2025-211

Published: 2025

Journal Articles

Construction and validation of a prediction model for extracorporeal circuit clotting risk during regional citrate anticoagulation in continuous renal replacement therapy for critically ill patients with hematological disorders

Jian Zhang, Xiaoying Wang, Jianxiong Hong, Yanan Feng, Bin Zhang, Jiajing Wang, Yijun Song

Blood (2025) 146 (Supplement 1): 6166.

https://doi.org/10.1182/blood-2025-6166

Published: 2025

Journal Articles

Microrna-142 improves IL1RAP CAR-T cell activity in Acute Myeloid Leukemia

Kaito Harada, Dandan Zhao, Miso Park, Fang Chen, Yongfang Xu, Yi Zhang, Yile Zhou, Bea Parcutela, Yead Jewel, Ashlie Munoz, Idoroenyi Amanam, Le Xuan Truong Nguyen, Jianjun Chen, Lucy Ghoda, Stephen Forman, John Williams, Bin Zhang, Guido Marcucci

Blood (2025) 146 (Supplement 1): 2340.

https://doi.org/10.1182/blood-2025-2340

Published: 2025

Journal Articles

Phase II, single-arm, open-label, multicenter study: Efficacy of adjunctive Bruton's tyrosine kinase inhibitor (BTKi) zanubrutinib and chimeric antigen receptor (CART) in aggressive B-cell non-hodgkins lymphoma (aNHL)

Reem Karmali, Carlos Galvez, Jane Winter, Shuo Ma, Bin Zhang, Ping Xie, Yangruijue (Anna) Ma, Ruohui Chen, Nirav Shah, Leo Gordon

Blood (2025) 146 (Supplement 1): 1010.

https://doi.org/10.1182/blood-2025-1010

Published: 2025

Journal Articles

Optimizing Bcl11b timing enhances natural killer cell differentiation and cytotoxicity from human pluripotent stem cells for effective immunotherapy

Akhilesh Kumar, Bin Zhang, Andrew Baldys, Colin Fischer, Alexander Lenvik, Martin Felices, Zachary Davis, Laura Bendzick, Anna Weis, Yenan Bryceson, Jeffrey Miller, Frank Cichocki

Blood (2025) 146 (Supplement 1): 3153.

https://doi.org/10.1182/blood-2025-3153

Published: 2025

Journal Articles

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

Blood (2025) 146 (Supplement 1): 2539.

https://doi.org/10.1182/blood-2025-2539

Published: 2025

Journal Articles

Chronic myeloid leukemia (CML) evolution is not encoded in single-cell microstates, but emerges from population-level macrostates

David Frankhouser, Dandan Zhao, Yu-Hsuan Fu, Anupam Dey, Ziang Chen, Jihyun Irizarry, Jennifer Rangel Ambriz, Sergio Branciamore, Denis O'Meally, Jeffrey Trent, Stephen Forman, Ya-Huei Kuo, Adam MacLean, Bin Zhang, Russell Rockne, Guido Marcucci

Blood (2025) 146 (Supplement 1): 5026.

https://doi.org/10.1182/blood-2025-5026

Published: 2025

Journal Articles

Allosteric inhibition of RAN decreases mir-126 biogenesis in endothelial cells and controls Acute Myeloid Leukemia growth

Melissa Valerio, Guido Marcucci, Le Xuan Truong Nguyen, Nagarajan Vaidehi, Wenyuan Wei, Hyunjun Kang, Ning Ma, Supriyo Bhattacharya, Genevieve Baker, Weidong Hu, Lianjun Zhang, Dinh Hoang Hoa, Bin Zhang, J. Jefferson Perry, Jia Feng, Hongyu Zhang

Blood (2025) 146 (Supplement 1): 3294.

https://doi.org/10.1182/blood-2025-3294

Published: 2025

Journal Articles

Immunoglobulin variable gene diversity reflects distinct metabolic/signaling states and impacts measurable residual disease monitoring and clinical outcome in B cell acute lymphoblastic leukemia

Blood (2025) 146 (Supplement 1): 333.

https://doi.org/10.1182/blood-2025-333

Published: 2025

Journal Articles

Evaluating ribosomal readthrough as a precision medicine strategy for restoring factor VIII expression in hemophilia a

Zhigang Liu, Vishal Srivastava, Aabid Hussain, Bin Zhang

Blood (2025) 146 (Supplement 1): 4829.

https://doi.org/10.1182/blood-2025-4829

Published: 2025

Journal Articles

From theory to therapy: Predicting response to chemotherapy with multiomic longitudinal profiling of peripheral blood in AML

Jennifer Rangel Ambriz, Ziang Chen, Yu-Hsuan Fu, David Frankhouser, Denis O'Meally, Sergio Branciamore, Jihyun Irizarry, Bin Zhang, Lianjun Zhang, Ying-Chieh Chen, Guido Marcucci, Russell Rockne, Ya-Huei Kuo

Blood (2025) 146 (Supplement 1): 5284.

https://doi.org/10.1182/blood-2025-5284

Published: 2025

Journal Articles

Loss of endothelial mir-126 drives age-related reduction of hematopoietic activity

Dandan Zhao, Le Xuan Truong Nguyen, Xubo Gong, Fang Chen, Min-Hsuan Chen, Guido Marcucci, Bin Zhang

Blood (2025) 146 (Supplement 1): 1392.

https://doi.org/10.1182/blood-2025-1392

Published: 2025

Journal Articles

Cytokine profiling identifies an IL‑8/IL1RAP‑Pathway–Linked inflammatory phenotype in myeloproliferative neoplasms (MPN) associated with high symptom burden and poor outcomes

Idoroenyi Amanam, Lucy Ghoda, Salman Otoukesh, Yile Zhou, Bin Zhang, Dauh-Lian Chi, Tim Synold, John Williams, Monzr M. Al Malki, Haris Ali, Guido Marcucci

Blood (2025) 146 (Supplement 1): 5593.

https://doi.org/10.1182/blood-2025-5593

Published: 2025

Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Blood (2024) 144 (Supplement 1): 625.

https://doi.org/10.1182/blood-2024-201916

Published: 2024

Journal Articles

Disrupting Mitochondrial Dynamics and Metabolism in Leukemic Stem Cells through Mitochondrial PCNA Inhibition: The Role of AOH1996

Hyunjun Kang, Melissa Valerio, Jia Feng, Long Gu, Dinh Hoa Hoang, Shawn Sharkas, Khyatiben V. Pathak, Jennifer Jossart, Yuriy Shostak, Zhuo Li, Bin Zhang, Patrick Pirrotte, Jefferson Perry, Robert Hickey, Linda H Malkas, Guido Marcucci, Le Xuan Truong Nguyen

Blood (2024) 144 (Supplement 1): 210.

https://doi.org/10.1182/blood-2024-211269

Published: 2024

Journal Articles

Acquired microRNA (miR)-142 Deficit Drives Immune Escape in Acute Myeloid Leukemia (AML)

Fang Chen, Dandan Zhao, Yongfang Xu, Huafeng Wang, Shawn Sharkas, Le Xuan Truong Nguyen, Lucy Y. Ghoda, Mark Boldin, Guido Marcucci, Bin Zhang

Blood (2024) 144 (Supplement 1): 2944.

https://doi.org/10.1182/blood-2024-210855

Published: 2024

Journal Articles

Buprenorphine Is Associated with Lower Home Opioid Use and Acute Care Utilization in Sickle Cell Disease

Charleen Jacobs, Brittany McCrary, Mikayla Gordon Wexler, Angela Liu, Elizabeth Stidham, Sarah McCuskee, Jeffrey A. Glassberg, Susanna Curtis, Bin Zhang

Blood (2024) 144 (Supplement 1): 2514.

https://doi.org/10.1182/blood-2024-193332

Published: 2024

Journal Articles

Deficit of microRNA (miR)-142 Promotes Transformation of Clonal Myeloid Disorder into Acute Myeloid Leukemia (AML)

Yongfang Xu, Huafeng Wang, Fang Chen, Jihyun Irizarry, Shawn Sharkas, Dandan Zhao, Mark Boldin, Guido Marcucci, Bin Zhang

Blood (2024) 144 (Supplement 1): 348.

https://doi.org/10.1182/blood-2024-211467

Published: 2024

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ST2 promotes leukemia transformation by reshaping the immune landscape in Acute Myeloid Leukemia

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

Construction and validation of a prediction model for extracorporeal circuit clotting risk during regional citrate anticoagulation in continuous renal replacement therapy for critically ill patients with hematological disorders

Microrna-142 improves IL1RAP CAR-T cell activity in Acute Myeloid Leukemia

Phase II, single-arm, open-label, multicenter study: Efficacy of adjunctive Bruton's tyrosine kinase inhibitor (BTKi) zanubrutinib and chimeric antigen receptor (CART) in aggressive B-cell non-hodgkins lymphoma (aNHL)

Optimizing Bcl11b timing enhances natural killer cell differentiation and cytotoxicity from human pluripotent stem cells for effective immunotherapy

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

Chronic myeloid leukemia (CML) evolution is not encoded in single-cell microstates, but emerges from population-level macrostates

Allosteric inhibition of RAN decreases mir-126 biogenesis in endothelial cells and controls Acute Myeloid Leukemia growth

Immunoglobulin variable gene diversity reflects distinct metabolic/signaling states and impacts measurable residual disease monitoring and clinical outcome in B cell acute lymphoblastic leukemia

Evaluating ribosomal readthrough as a precision medicine strategy for restoring factor VIII expression in hemophilia a

From theory to therapy: Predicting response to chemotherapy with multiomic longitudinal profiling of peripheral blood in AML

Loss of endothelial mir-126 drives age-related reduction of hematopoietic activity

Cytokine profiling identifies an IL‑8/IL1RAP‑Pathway–Linked inflammatory phenotype in myeloproliferative neoplasms (MPN) associated with high symptom burden and poor outcomes

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Disrupting Mitochondrial Dynamics and Metabolism in Leukemic Stem Cells through Mitochondrial PCNA Inhibition: The Role of AOH1996

Acquired microRNA (miR)-142 Deficit Drives Immune Escape in Acute Myeloid Leukemia (AML)

Buprenorphine Is Associated with Lower Home Opioid Use and Acute Care Utilization in Sickle Cell Disease

Deficit of microRNA (miR)-142 Promotes Transformation of Clonal Myeloid Disorder into Acute Myeloid Leukemia (AML)

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American Society of Hematology

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