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Journal Articles

Donor-derived CD7 CAR T cells for pediatric and adult relapsed/refractory T-ALL/LBL: a phase 2 trial

Blood (2025) 146 (23): 2745–2757.

https://doi.org/10.1182/blood.2025029299

Published: 2025

Includes: Supplemental data

Journal Articles

Leukemia escapes immunity by imposing a type 1 regulatory program on neoantigen-specific CD4 + T cells

Hrishi Venkatesh, Enoc Granados Centeno, Qianyun Luo, Miriam Arroyo, Lynn Heltemes-Harris, Todd P. Knutson, Yinjie Qiu, Allison Haaning, Beau R. Webber, Veronika Bachanova, Michael A. Farrar, Sean I. Tracy

Blood (2025) 146 (23): 2779–2793.

https://doi.org/10.1182/blood.2024028194

Published: 2025

Includes: Supplemental data

Journal Articles

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCT

Duneia McManus, Sabrina N. Copsel, Brent J. Pfeiffer, Dietlinde Wolf, Henry Barreras, Symon Ma, Ali Khodor, Seitaro Komai, Marina Burgos da Silva, Hajar Hazime, Miguel Gallardo, Sarah Grace Lime, Marcel R. M. van den Brink, Jung-Hyun Park, Maria T. Abreu, Geoffrey R. Hill, Victor L. Perez, Robert B. Levy

Blood (2025) 146 (22): 2710–2727.

https://doi.org/10.1182/blood.2025028418

Published: 2025

Includes: Supplemental data

Journal Articles

Innate lymphoid cells prevent graft-versus-host disease via IL-9–driven T-cell senescence

Dejene M. Tufa, Eric Hoffmeyer, Kristin L. Schaller, Ben Kooiman, Elena Woods, Dong Wang, Dallas Jones, Spencer Hall, Joselyn Cruz Cruz, Michael R. Verneris

Blood (2025) 146 (22): 2656–2669.

https://doi.org/10.1182/blood.2025028504

Published: 2025

Includes: Supplemental data

Journal Articles

Prostaglandins in cancer revisited: principles of production, mechanisms of immune regulation, and therapeutic perspectives

Erik Müller, Bastian Kruse, Jan P Böttcher

Blood blood.2025029806.

https://doi.org/10.1182/blood.2025029806

Published: 2025

Journal Articles

Long-term Follow-up of Gastrointestinal CAR T-cell Lymphoma: Homing, Clonal Expansion, and Response to Cyclosporine

Hitomi Hosoya, Armando N Bastidas Torres, Sebastian Fernandez-Pol, John Mark Gubatan, Safa Najidh, George E Duran, Fei Dong, Zachary Ehlinger, Claire Lohman, Charles Wright, III, Bita Sahaf, Crystal L. Mackall, David B Miklos, Surbhi Sidana, David M Kurtz, Michael S Khodadoust, Lehka Mikkilineni

Blood blood.2025031423.

https://doi.org/10.1182/blood.2025031423

Published: 2025

Includes: Supplemental data

Journal Articles

Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence

Blood (2025) 146 (21): 2531–2543.

https://doi.org/10.1182/blood.2025028683

Published: 2025

Includes: Supplemental data

Journal Articles

A T-cell–based metric of immune age predicts outcomes in older patients with myeloma receiving daratumumab-based therapy

Wassilis S. C. Bruins, Febe Smits, Carolien Duetz, Kaz Groen, Charlotte L. B. M. Korst, A. Vera de Jonge, Christie P. M. Verkleij, Rosa Rentenaar, Meliha Cosovic, Merve Eken, Inoka Twickler, Paola M. Homan-Weert, Pieter Sonneveld, Philippe Moreau, Jürgen Claesen, Niels W. C. J. van de Donk, Sonja Zweegman, Tuna Mutis

Blood (2025) 146 (21): 2517–2530.

https://doi.org/10.1182/blood.2025028587

Published: 2025

Includes: Supplemental data

Journal Articles

A phase 2 study of zanubrutinib in combination with rituximab and lenalidomide in de novo diffuse large B-cell lymphoma

Peng-Peng Xu, Yue Zhu, Zi-Yang Shi, Li Wang, Shu Cheng, Ying Qian, Yan Zhao, Yang He, Hong-Mei Yi, Bin-shen Ou-yang, Xu-Feng Jiang, Biao Li, Qi Song, Rong-Ji Mu, Wei-Li Zhao

Blood (2025) 146 (21): 2561–2573.

https://doi.org/10.1182/blood.2025028649

Published: 2025

Includes: Supplemental data

Journal Articles

Deciphering neutrophil dynamics in the focal lesion tumor microenvironment to overcome immunosuppression in multiple myeloma

Joshua Rivera, Qi Yan, Saeed Daneshmandi, Romain Lannes, Eriko Katsuta, JeeEun Choi, Prashant Singh, Ahmed Belal, Ronald Alberico, Ian Lund, Megan Schaefer, Hamza Hassan, Sarah Parker, Kenneth C. Anderson, Nikhil C. Munshi, Mehmet Samur, Philip L. McCarthy, Jens Hillengass, Hemn Mohammadpour

Blood (2025) 146 (20): 2392–2405.

https://doi.org/10.1182/blood.2025028963

Published: 2025

Includes: Supplemental data

Journal Articles

Mitochondrial DNA via recipient TLR9 acts as a potent first hit in murine transfusion-related acute lung injury

Johan Rebetz, Hilma Cederholm, David McGauran, Ellen Moore, Catherine Chi, Karlijn Tabak, Maria Allhorn, Martin L. Olsson, Arne Egesten, John W. Semple, Genevieve Marcoux

Blood (2025) 146 (20): 2479–2490.

https://doi.org/10.1182/blood.2025028794

Published: 2025

Includes: Supplemental data

Journal Articles

A BCMA-mRNA vaccine is a promising therapeutic for multiple myeloma

Debasmita Dutta, Jiye Liu, Kenneth Wen, Arghya Ray, Alessandro Salatino, Xiangdong Liu, Annamaria Gulla, Teru Hideshima, Yan Song, Kenneth C. Anderson

Blood (2025) 146 (19): 2322–2335.

https://doi.org/10.1182/blood.2025028597

Published: 2025

Includes: Supplemental data

Journal Articles

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrins

Janita J. Oosterhoff, Wendy Stam, Suze R. van Brummelen, Arthur E. H. Bentlage, Thijs de Vos, José María de Pereda, Leendert Porcelijn, Rick Kapur, Masja de Haas, C. Ellen van der Schoot, Gestur Vidarsson, Coert Margadant

Blood (2025) 146 (18): 2189–2202.

https://doi.org/10.1182/blood.2025029618

Published: 2025

Includes: Supplemental data

Journal Articles

Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease

Blood (2025) 146 (17): 2047–2062.

https://doi.org/10.1182/blood.2025028562

Published: 2025

Includes: Supplemental data

Journal Articles

Sequential targeting in multiple myeloma: talquetamab, a GPRC5D bispecific antibody, as a bridge to BCMA CAR-T therapy

Blood (2025) 146 (17): 2063–2072.

https://doi.org/10.1182/blood.2025029773

Published: 2025

Includes: Supplemental data

Journal Articles

Clinical presentation, management, and outcome of TIAN in CNS lymphoma treated with CD19-CAR T-cell therapy

Blood (2025) 146 (16): 1902–1913.

https://doi.org/10.1182/blood.2025028964

Published: 2025

Includes: Supplemental data

Journal Articles

The interleukin-33 receptor (ST2) is a novel therapeutic target to attenuate the progression of hemophilic arthropathy

Blood (2025) 146 (16): 1979–1990.

https://doi.org/10.1182/blood.2024027578

Published: 2025

Includes: Supplemental data

Journal Articles

Safety and efficacy of elranatamab in patients with relapsed and/or refractory immunoglobulin light-chain amyloidosis

Pedro Vianna, Rajshekhar Chakraborty, Shahrier Hossain, Divaya Bhutani, Shannon Miller, Annemarie Rossi, Sarah A. M. Cuddy, Rodney H. Falk, Suzanne Lentzsch, Jacob P. Laubach, Giada Bianchi

Blood (2025) 146 (16): 1929–1935.

https://doi.org/10.1182/blood.2025028383

Published: 2025

Includes: Supplemental data

Journal Articles

Impaired cytotoxic function and exhausted phenotype of natural killer cells in VEXAS syndrome

Blood (2025) 146 (16): 1950–1963.

https://doi.org/10.1182/blood.2024028216

Published: 2025

Includes: Supplemental data

Journal Articles

Ramantamig (JNJ-79635322), a novel T-cell-engaging trispecific antibody targeting BCMA, GPRC5D, and CD3, in multiple myeloma models

Kodandaram Pillarisetti, Danlin Yang, Leopoldo Luistro, Jianhong Yao, Melissa Smith, Peter Vulfson, James Testa, Jr, Randolph Ponticiello, Scott R Brodeur, Bradley Heidrich, Kathryn Packman, Sanjaya Singh, Ricardo M Attar, Yusri A Elsayed, Ulrike Philippar

Blood blood.2025030027.

https://doi.org/10.1182/blood.2025030027

Published: 2025

Includes: Supplemental data

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Donor-derived CD7 CAR T cells for pediatric and adult relapsed/refractory T-ALL/LBL: a phase 2 trial

Leukemia escapes immunity by imposing a type 1 regulatory program on neoantigen-specific CD4 + T cells

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCT

Innate lymphoid cells prevent graft-versus-host disease via IL-9–driven T-cell senescence

Prostaglandins in cancer revisited: principles of production, mechanisms of immune regulation, and therapeutic perspectives

Long-term Follow-up of Gastrointestinal CAR T-cell Lymphoma: Homing, Clonal Expansion, and Response to Cyclosporine

Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence

A T-cell–based metric of immune age predicts outcomes in older patients with myeloma receiving daratumumab-based therapy

A phase 2 study of zanubrutinib in combination with rituximab and lenalidomide in de novo diffuse large B-cell lymphoma

Deciphering neutrophil dynamics in the focal lesion tumor microenvironment to overcome immunosuppression in multiple myeloma

Mitochondrial DNA via recipient TLR9 acts as a potent first hit in murine transfusion-related acute lung injury

A BCMA-mRNA vaccine is a promising therapeutic for multiple myeloma

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrins

Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease

Sequential targeting in multiple myeloma: talquetamab, a GPRC5D bispecific antibody, as a bridge to BCMA CAR-T therapy

Clinical presentation, management, and outcome of TIAN in CNS lymphoma treated with CD19-CAR T-cell therapy

The interleukin-33 receptor (ST2) is a novel therapeutic target to attenuate the progression of hemophilic arthropathy

Safety and efficacy of elranatamab in patients with relapsed and/or refractory immunoglobulin light-chain amyloidosis

Impaired cytotoxic function and exhausted phenotype of natural killer cells in VEXAS syndrome

Ramantamig (JNJ-79635322), a novel T-cell-engaging trispecific antibody targeting BCMA, GPRC5D, and CD3, in multiple myeloma models

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American Society of Hematology

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