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Journal Articles

Secondary graft failure after PT-cy: Modeling a candidate risk assignment biomarker based on lymphocyte reconstitution. Results from the BMT CTN 1801 study.

Blood (2025) 146 (Supplement 1): 4198.

https://doi.org/10.1182/blood-2025-4198

Published: 2025

Journal Articles

A TLR4-HSP70 efferocytic program in thymic macrophages sustains thymic homeostasis and T cell output

Andri Leo Lemarquis, Daniel Ghazarian, Miriam Martinez, Nastaran Abbasizadeh, Brianna Gipson, Ashley Huang, Jennifer Funes, Itauá Leston Araujo, Susan DeWolf, Kimon Argyropoulos, Scott James, Laura Hale, Anastasia Kousa, Jarrod Dudakov, Marcel van den Brink

Blood (2025) 146 (Supplement 1): 160.

https://doi.org/10.1182/blood-2025-160

Published: 2025

Journal Articles

CAR T cells converge on a distinct transcriptional state over time in patients with diverse hematologic malignancies

Xiaoli Mi, Dennis Yuan, Nicholas Midler, Alexander Lewis, Rebecca Murray, Alyssa Indart, Kenyon Weis, Olga Shestova, Susan DeWolf, Jae Park, Omar Abdel-Wahab, Saar Gill, Dan Avi Landau

Blood (2025) 146 (Supplement 1): 499.

https://doi.org/10.1182/blood-2025-499

Published: 2025

Journal Articles

Non-hematotoxic Tim-3/CD70 dual-targeting CAR T cells promote potent anti-leukemia activity against acute myeloid leukemia

Sophia Chen, Adhithi Rajagopalan, Katerina Su, Anastasia Kousa, Preet Kaur, Ryan Lee, Jacob Fischman, Alyssa Massa, Dylan Manuele, Brandon Ng, Alexander Boardman, Susan DeWolf, Judith Hecker, Peter Fridy, Michael Rout, Brian Chait, Marcel van den Brink, Scott James

Blood (2025) 146 (Supplement 1): 2345.

https://doi.org/10.1182/blood-2025-2345

Published: 2025

Journal Articles

Combined TCR-seq and single-cell RNA-seq reveal distinct origins for antiviral immunity after post-transplant cyclophosphamide and tac/MTX gvhd prophylaxis: Results from the BMT CTN 1801 study

Blood (2025) 146 (Supplement 1): 818.

https://doi.org/10.1182/blood-2025-818

Published: 2025

Journal Articles

Development of CD371 shielded hematopoietic stem cell grafts for protection against AML-directed immunotherapies

Satoshi Kaito, Karen Li, Xiaoli Mi, Cynthia Castro, Nina Fox, Alexander Lewis, Adriana Cuibus, Kenyon Weis, Erin Burns, Sarah Yoo, Jahan Rahman, Susan DeWolf, Anthony Daniyan, Omar Abdel-Wahab

Blood (2025) 146 (Supplement 1): 2309.

https://doi.org/10.1182/blood-2025-2309

Published: 2025

Journal Articles

CD371-Targeted CAR T cells Secreting Interleukin-18 Exhibit Robust Expansion and Clear Refractory Acute Myeloid Leukemia

Blood blood.2025029532.

https://doi.org/10.1182/blood.2025029532

Published: 2025

Includes: Supplemental data

Journal Articles

A new variable to study in transplant: APOE variant status

Satoshi Kaito, Susan DeWolf

Blood (2025) 145 (17): 1839–1840.

https://doi.org/10.1182/blood.2025028406

Published: 2025

Journal Articles

Patterns of Immune Reconstitution and Their Clinical Significance in Aggressive Lymphoma Treated with CAR-T Therapy

Blood (2024) 144 (Supplement 1): 2034.

https://doi.org/10.1182/blood-2024-205548

Published: 2024

Journal Articles

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Blood (2024) 144 (Supplement 1): 343.

https://doi.org/10.1182/blood-2024-198639

Published: 2024

Journal Articles

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Blood (2024) 144 (Supplement 1): 371.

https://doi.org/10.1182/blood-2024-204143

Published: 2024

Journal Articles

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

Blood (2024) 144 (Supplement 1): 671.

https://doi.org/10.1182/blood-2024-202224

Published: 2024

Journal Articles

Dual-Vector-Transduction with Single-Step Magnetic Selection (Zip-sort) Increases Transgenic Payloads to Enhance CAR T Cell Activity

Blood (2024) 144 (Supplement 1): 501.

https://doi.org/10.1182/blood-2024-208357

Published: 2024

Journal Articles

Single-Cell Spatial Transcriptomics Identifies Lymphoid Aggregates with Location-Specific Alterations of Adaptive Immune Cells in Human MDS Bone Marrow

Blood (2024) 144 (Supplement 1): 817.

https://doi.org/10.1182/blood-2024-203714

Published: 2024

Journal Articles

Regulatory T Cell Derived Trefoil Factor 1 Drives Thymic Regeneration in Allogeneic Hematopoietic Cell Transplantation

Jonah Pierce, Brianna Gipson, Lucia Serrano-Marin, Kimon V Argyropoulos, Susan DeWolf, Scott E. James, Manpreet Kaur, Anastasia Kousa, Chi L Nguyen, Adhithi Rajagopalan, Kristen Victor, Kenyon Weis, Andri Leo L Lemarquis, Marcel R.M. van den Brink

Blood (2024) 144 (Supplement 1): 2010.

https://doi.org/10.1182/blood-2024-202774

Published: 2024

Journal Articles

CD371-Targeted CAR T-Cells Secreting Interleukin-18 Exhibit Robust Expansion and Disease Clearance in Patients with Refractory Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 2070.

https://doi.org/10.1182/blood-2024-194162

Published: 2024

Journal Articles

Cross-Talk between Leukemic Blasts and T Cells Drives Targetable T Cell Dysfunction in the AML Tumor Microenvironment

Blood (2024) 144 (Supplement 1): 637.

https://doi.org/10.1182/blood-2024-194037

Published: 2024

Journal Articles

IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model

Brandon D. Ng, Adhithi Rajagopalan, Anastasia I. Kousa, Jacob S. Fischman, Sophia Chen, Alyssa Massa, Harold K. Elias, Dylan Manuele, Michael Galiano, Andri L. Lemarquis, Alexander P. Boardman, Susan DeWolf, Jonah Pierce, Bjarne Bogen, Scott E. James, Marcel R. M. van den Brink

Blood (2024) 144 (2): 171–186.

https://doi.org/10.1182/blood.2023022293

Published: 2024

Includes: Supplemental data

Journal Articles

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Blood (2023) 142 (Supplement 1): 475.

https://doi.org/10.1182/blood-2023-188032

Published: 2023

Journal Articles

Low CD117 Expression Identifies Hematopoietic Stem Cell Subsets with Enhanced Lymphoid Potential in Mice and Humans

Harold K Elias, Sneha Mitra, Brianna Gipson, Marina Burgos da Silva, Nicole Lee, Mohamed A.E. Ali, Simon Grassman, Anastasia Kousa, Susan DeWolf, Christopher Y. Park, Joseph Sun, Christina Leslie, Avinash Bhandoola, Marcel R.M. van den Brink

Blood (2023) 142 (Supplement 1): 3417.

https://doi.org/10.1182/blood-2023-190000

Published: 2023

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Secondary graft failure after PT-cy: Modeling a candidate risk assignment biomarker based on lymphocyte reconstitution. Results from the BMT CTN 1801 study.

A TLR4-HSP70 efferocytic program in thymic macrophages sustains thymic homeostasis and T cell output

CAR T cells converge on a distinct transcriptional state over time in patients with diverse hematologic malignancies

Non-hematotoxic Tim-3/CD70 dual-targeting CAR T cells promote potent anti-leukemia activity against acute myeloid leukemia

Combined TCR-seq and single-cell RNA-seq reveal distinct origins for antiviral immunity after post-transplant cyclophosphamide and tac/MTX gvhd prophylaxis: Results from the BMT CTN 1801 study

Development of CD371 shielded hematopoietic stem cell grafts for protection against AML-directed immunotherapies

CD371-Targeted CAR T cells Secreting Interleukin-18 Exhibit Robust Expansion and Clear Refractory Acute Myeloid Leukemia

A new variable to study in transplant: APOE variant status

Patterns of Immune Reconstitution and Their Clinical Significance in Aggressive Lymphoma Treated with CAR-T Therapy

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

A High-Fiber Dietary Intervention (NUTRIVENTION) in Precursor Plasma Cell Disorders Improves Biomarkers of Disease and May Delay Progression to Myeloma

Dual-Vector-Transduction with Single-Step Magnetic Selection (Zip-sort) Increases Transgenic Payloads to Enhance CAR T Cell Activity

Single-Cell Spatial Transcriptomics Identifies Lymphoid Aggregates with Location-Specific Alterations of Adaptive Immune Cells in Human MDS Bone Marrow

Regulatory T Cell Derived Trefoil Factor 1 Drives Thymic Regeneration in Allogeneic Hematopoietic Cell Transplantation

CD371-Targeted CAR T-Cells Secreting Interleukin-18 Exhibit Robust Expansion and Disease Clearance in Patients with Refractory Acute Myeloid Leukemia

Cross-Talk between Leukemic Blasts and T Cells Drives Targetable T Cell Dysfunction in the AML Tumor Microenvironment

IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Low CD117 Expression Identifies Hematopoietic Stem Cell Subsets with Enhanced Lymphoid Potential in Mice and Humans

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