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John Levine
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Journal Articles

Secondary graft failure after PT-cy: Modeling a candidate risk assignment biomarker based on lymphocyte reconstitution.  Results from the BMT CTN 1801 study.

Free
Kayleigh Ingersoll Omdahl, Steven Siegel, Jiayi Dong, Susan DeWolf, Kyle Hebert, Donna Neuberg, Isabella Schichter, Alexandre Albanese, Paul Keskula, Lorenzo Cagnin, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung Choi, William Clark, Suman Das, Robert Jenq, Richard Jones, John Levine, Brent Logan, Michael Martens, Hemant Murthy, Armin Rashidi, Marcie Riches, Wael Saber, Karamjeet Sandhu, Anthony Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian Shaffer, Andrew Rezvani, Najla El Jurdi, Alison Loren, Mary Horowitz, Javier Bolanos-Meade, Shernan Holtan, Ami Bhatt, Miguel-Angel Perales, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2025-4198
Published: 2025
Journal Articles

Evaluating thymic stromal lymphopoietin (TSLP) as a biomarker in acute graft versus host disease

Free
Parveen Shiraz, Ioannis Louloudis, Joanna Liliental, Shailja Patel, Alexandria Jensen, Sonia Fonseca, Kathy Le, Binta Diallo, Anna Pavlova, Sally Arai, Robert Negrin, Andrew Rezvani, Laura Johnston, Wen-Kai Weng, Robert Lowsky, Lori Muffly, David Miklos, Vanessa Kennedy, Everett Meyer, John Levine, James Ferrara, Judith Shizuru
Journal: Blood
Blood (2025) 146 (Supplement 1): 586.
https://doi.org/10.1182/blood-2025-586
Published: 2025
Journal Articles

Mismatched unrelated and haploidentical transplant with post-transplant cyclophosphamide-based graft versus host disease prophylaxis are effective for myelofibrosis

Free
Richard Sheppard, Noa Rippel, Hulya Kocyigit, Erin Moshier, Kyle Wiatrowski, John Levine, John Mascarenhas, Ronald Hoffman, Alla Keyzner
Journal: Blood
Blood (2025) 146 (Supplement 1): 2530.
https://doi.org/10.1182/blood-2025-2530
Published: 2025
Journal Articles

IL-39/IL-39R signaling drives acute graft-versus-host disease

Free
Denggang Fu, Michael Martens, Michael Hendrix, Allison Pugel, Qiao Cheng, Amin Alousi, Iskra Pusic, George Carrum, Asad Bashey, Stephanie Lee, John Levine, Yongxia Wu, Mehdi Hamadani, Xue-Zhong Yu
Journal: Blood
Blood (2025) 146 (Supplement 1): 5865.
https://doi.org/10.1182/blood-2025-5865
Published: 2025
Journal Articles

Grade I acute graft-vs-host disease: Treat or not?

Free
Yu Akahoshi, Nikolaos Katsivelos, Ioannis Evangelos Louloudis, Daniela Weber, Francis Ayuk, William Hogan, Yi-Bin Chen, Aaron Etra, Paibel Aguayo-Hiraldo, Chantiya Chanswangphuwana, Hannah Choe, Elizabeth Hexner, Carrie Kitko, Monzr M. Al Malki, Pietro Merli, Timothy Olson, Muna Qayed, Ingrid Vasova, Matthias Woelfl, Janna Baez, Gilbert Eng, Sigrun Gleich, George Morales, Nikolaos Spyrou, Rachel Young, Ryotaro Nakamura, James Ferrara, John Levine
Journal: Blood
Blood (2025) 146 (Supplement 1): 2461.
https://doi.org/10.1182/blood-2025-2461
Published: 2025
Journal Articles

Combined TCR-seq and single-cell RNA-seq reveal distinct origins for antiviral immunity after post-transplant cyclophosphamide and tac/MTX gvhd prophylaxis: Results from the BMT CTN 1801 study

Free
Steven Siegel, Susan DeWolf, Joseph Schmalz, Nicholas Winn, James Kaminski, Stephanie Bien, Catherine Sanders, Harlan Robins, Jillian Zavistaski, Isabella Schichter, Lea Steinberg, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung Choi, William Clark, Suman Das, Robert Jenq, Richard Jones, John Levine, Brent Logan, Michael Martens, Hemant Murthy, Armin Rashidi, Marcie Riches, Wael Saber, Karamjeet Sandhu, Anthony Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian Shaffer, Andrew Rezvani, N El Jurdi, Alison Loren, Mary Horowitz, Mehdi Hamadani, Javier Bolanos-Meade, Shernan Holtan, Ami Bhatt, Miguel-Angel Perales, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 818.
https://doi.org/10.1182/blood-2025-818
Published: 2025
Journal Articles

Post-transplant maintenance with sorafenib is safe and effective in pediatric patients with har FLT3/ITD AML: A report from the Children's oncology group protocol AAML1031

Free
Caitlin Elgarten, Todd Alonzo, Robert Gerbing, John Choi, Brian Fisher, Betsy Hirsch, Samir Kahwash, John Levine, Lisa Brodersen, Michael Loken, Susana Raimondi, Katherine Tarlock, Andrew Wood, Lillian Sung, Todd Cooper, Alan Gamis, Soheil Meshinchi, Richard Aplenc, Jessica Pollard
Journal: Blood
Blood (2025) 146 (Supplement 1): 1644.
https://doi.org/10.1182/blood-2025-1644
Published: 2025
Journal Articles

Refinement of Day 28 Treatment Response Criteria for Acute GVHD: A Collaboration Study of the JSTCT and MAGIC

Free
Yu Akahoshi, Yoshihiro Inamoto, Nikolaos Spyrou, Hideki Nakasone, Francis A. Ayuk, Hannah Choe, Noriko Doki, Tetsuya Eto, Aaron Etra, Elizabeth O. Hexner, Nobuhiro Hiramoto, William J. Hogan, Ernst Holler, Keisuke Kataoka, Masatsugu Tanaka, Takashi Tanaka, Naoyuki Uchida, Ingrid Vasova, Fumihiko Ishimaru, Takahiro Fukuda, Yi-Bin Chen, Junya Kanda, Ryotaro Nakamura, Yoshiko Atsuta, James L.M. Ferrara, Yoshinobu Kanda, John Levine, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 384.
https://doi.org/10.1182/blood-2024-203344
Published: 2024
Journal Articles

Serial Clinical and Biomarker Monitoring during Treatment Can Stratify Patients with Low Risk Gvhd

Free
Nikolaos Katsivelos, Nikolaos Spyrou, Daniela Weber, Ingrid Vasova, Francis A. Ayuk, Hannah Choe, William J. Hogan, Zachariah Defilipp, Muna Qayed, Aaron Etra, Karamjeet S Sandhu, Sabrina Kraus, Timothy S. Olson, Elizabeth O. Hexner, Paibel Aguayo-Hiraldo, Ran Reshef, Evelyn Ullrich, Tal Schechter-Finkelstein, Carrie L. Kitko, Chantiya Chanswangphuwana, Pietro Merli, Yu Akahoshi, Janna Baez, Gilbert Eng, Rahnuma Beheshti, Steven Kowalyk, George Morales, Ioannis Evangelos Louloudis, Rachel Young, Ernst Holler, Ryotaro Nakamura, James L.M. Ferrara, John Levine
Journal: Blood
Blood (2024) 144 (Supplement 1): 380.
https://doi.org/10.1182/blood-2024-204010
Published: 2024
Journal Articles

Rabbit Antithymocyte (rATG) Exposure and Outcomes after Hematopoietic Cell Transplantation: A Real World Experience from BMT CTN 1202

Free
Madhavi Lakkaraja, Audrey Mauguen, Kinga K Hosszu, Devin McAvoy, Valerie Stewart, Gabrielle Schmidt, John Levine, Miguel-Angel Perales, Sergio A. Giralt, K. Scott Baker, Jaap Jan Boelens
Journal: Blood
Blood (2023) 142 (Supplement 1): 111.
https://doi.org/10.1182/blood-2023-182352
Published: 2023
Journal Articles

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Free
Leslie Kean, Steven J Siegel, Joseph T Schmalz, Stephanie A Bien, Danielle Scheffey, Catherine Sanders, Harlan Robins, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung W. Choi, William Clark, Suman r Das, Robert R. Jenq, Richard J. Jones, John Levine, Brent R. Logan, Hemant S. Murthy, Armin Rashidi, Marcie L. Riches, Wael Saber, Karamjeet S. Sandhu, Anthony D. Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian C. Shaffer, Andrew R. Rezvani, Najla El Jurdi, Alison Loren, Mary M. Horowitz, Javier Bolanos-Meade, Shernan G. Holtan, Ami S. Bhatt, Miguel-Angel Perales, Susan DeWolf
Journal: Blood
Blood (2023) 142 (Supplement 1): 475.
https://doi.org/10.1182/blood-2023-188032
Published: 2023
Journal Articles

The MAGIC Algorithm Probability Predicts Long-Term Outcomes and Treatment Response to Second-Line Therapy for Acute Gvhd

Free
Zachariah Defilipp, Haesook T. Kim, Nikolaos Spyrou, Steven Kowalyk, Gilbert Eng, Rahnuma Beheshti, Janna Baez, Francis A. Ayuk, Hannah Choe, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Muna Qayed, Ran Reshef, Ingrid Vasova, Robert Zeiser, Rachel Young, James L.M. Ferrara, Ryotaro Nakamura, John Levine, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 3576.
https://doi.org/10.1182/blood-2023-182300
Published: 2023
Journal Articles

Flares of Acute Graft-Versus-Host Disease: Mount Sinai Acute Gvhd International Consortium (MAGIC) Study

Free
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Udomsak Bunworasate, Hannah Choe, Matthias Eder, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Evelyn Ullrich, Ingrid Vasova, Matthias Woelfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John Levine, Ryotaro Nakamura
Journal: Blood
Blood (2023) 142 (Supplement 1): 776.
https://doi.org/10.1182/blood-2023-181900
Published: 2023
Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Free
Nikolaos Spyrou, Yu Akahoshi, Steven Kowalyk, George Morales, Rahnuma Beheshti, Paibel Aguayo-Hiraldo, MHD Monzr Al Malki, Francis Ayuketang Ayuk, Peter Bader, Janna Baez, Alexandra Capellini, Hannah Choe, Zachariah Defilipp, Matthias Eder, Gilbert Eng, Aaron Etra, Sigrun Gleich, Stephan Grupp, Elizabeth Hexner, Matthias Hoepting, William J. Hogan, Stelios Kasikis, Nikolaos Katsivelos, Carrie L. Kitko, Sabrina Kraus, Deukwoo Kwon, Pietro Merli, Joseph Portelli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Ingrid Vasova, Matthias Woelfl, Kitsada Wudhikarn, Rachel Young, Ernst Holler, Yi-Bin Chen, Ryotaro Nakamura, John Levine, James L.M. Ferrara
Journal: Blood
Blood (2023) 142 (Supplement 1): 779.
https://doi.org/10.1182/blood-2023-172955
Published: 2023
Journal Articles

Donor Hematopoietic Cell Telomere Length and Magnitude of Post-HCT Shortening Predict Survival in Early Stage Leukemia and Myelodysplastic Syndrome

Free
Shahinaz M. Gadalla, Hormuzd Katki, Tsung-Po Lai, Casey Dagnall, Caitrin Bupp, Amy Hutchinson, James Anderson, Kyra Mendez, Stephen R. Spellman, Valerie Stewart, Sharon Savage, Stephanie J. Lee, John Levine, Wael Saber, Abraham Aviv
Journal: Blood
Blood (2023) 142 (Supplement 1): 365.
https://doi.org/10.1182/blood-2023-189396
Published: 2023
Journal Articles

A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation

Free
CME
Muna Qayed, Kwang Woo Ahn, Carrie L. Kitko, Mariam H. Johnson, Nirali N. Shah, Christopher Dvorak, Karin Mellgren, Brian D. Friend, Michael R. Verneris, Wing Leung, Jacek Toporski, John Levine, Joseph Chewning, Alan Wayne, Urvi Kapoor, Brandon Triplett, Kirk R. Schultz, Gregory A. Yanik, Mary Eapen
Journal: Blood
Blood (2021) 137 (7): 983–993.
https://doi.org/10.1182/blood.2020009342
Published: 2021
Journal Articles

Clofarabine and busulfan conditioning facilitates engraftment and provides significant antitumor activity in nonremission hematologic malignancies

Free
Clinical Trials & Observations
John Magenau, Hiromi Tobai, Attaphol Pawarode, Thomas Braun, Edward Peres, Pavan Reddy, Carrie Kitko, Sung Choi, Gregory Yanik, David Frame, Andrew Harris, Harry Erba, Lisa Kujawski, Kojo Elenitoba-Johnson, Jennifer Sanks, Dawn Jones, Sophie Paczesny, James Ferrara, John Levine, Shin Mineishi
Journal: Blood
Blood (2011) 118 (15): 4258–4264.
https://doi.org/10.1182/blood-2011-06-358010
Published: 2011
Includes: Supplemental data
Journal Articles

A Prospective Study of G-CSF Primed Bone Marrow from Pediatric Donors as a Stem Cell Source for Allogeneic Bone Marrow Transplant: A Pediatric Blood and Marrow Transplant Consortium (PBMTC) Study.

Free
Haydar Frangoul, MD, Ann Woolfrey, MD, Shakila Khan, MD, Michael Pulsipher, MD, John Levine, MD, David Baker, MD, Mark Walters, MD, Mouhab Ayas, MD, Yaddanapudi Ravindranath, MD, Stephan Grupp, MD, PhD, Dean Billheimer, PhD, Eneida Nemecek, MD
Journal: Blood
Blood (2005) 106 (11): 1964.
https://doi.org/10.1182/blood.V106.11.1964.1964
Published: 2005