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Journal Articles

Plek2 as a novel downstream effector of p53: Targeting Plek2 ameliorates disease progression in p53-deficient myeloid malignancies

Pan Wang, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Inci Aydemir, Wenjie Cai, Laya Soleimani, Peng Ji

Blood (2025) 146 (Supplement 1): 216.

https://doi.org/10.1182/blood-2025-216

Published: 2025

Journal Articles

Spatial transcriptomic dissection of the myeloproliferative neoplasm niche uncovers mutant clone interactions and microenvironmental rewiring

Honghao Bi, Pan Wang, Ching Man Wai, Kehan Ren, Xu Han, Ermin Li, Laya Soleimani, Inci Aydemir, Wenjie Cai, Johanna Melo-Cardenas, Peng Ji

Blood (2025) 146 (Supplement 1): 3761.

https://doi.org/10.1182/blood-2025-3761

Published: 2025

Journal Articles

DHODH-driven pyrimidine metabolism is a targetable vulnerability in myeloproliferative neoplasms

Pan Wang, Xu Han, Inci Aydemir, Ermin Li, Honghao Bi, Kehan Ren, Wenjie Cai, Laya Soleimani, Peng Ji

Blood (2025) 146 (Supplement 1): 69.

https://doi.org/10.1182/blood-2025-69

Published: 2025

Journal Articles

Inflammatory remodeling and CD4+ T cell expansion in TET2-mutated myeloid disorders

Kehan Ren, Ermin Li, Xu Han, Yijie Liu, Honghao Bi, Pan Wang, Inci Aydemir, Madina Sukhanova, Peng Ji

Blood (2025) 146 (Supplement 1): 3162.

https://doi.org/10.1182/blood-2025-3162

Published: 2025

Journal Articles

Multicenter assessment of absolute neutrophil counts (ANC) and white blood cell counts (WBC) in healthy participants with the erythrocyte duffy null phenotype or genotype

Lauren Merz, Gilles Attipoe, Christina Barriteau, Michael Blechner, Eric Burks, Cecelia Calhoun, Sally Campbell Lee, Vivian Chang, Stella Chou, Adam Cuker, Emmanuel Fadeyi, Warren Fingrut, Victoria Forbes, Ivo Francischetti, Vijayakrishna Gadi, Richard Godby, Lucy Godley, Abraham Haimed, Hyojeong Han, Richard Haspel, Chibuzo Ilonze, Cyril Jacquot, Peng Ji, Justin Juskewitch, Matthew Karafin, Kimberly Klein, Nicole Kucine, Priya Kumar, Margarita Kushnir, David Levitz, Michael Lewis, Geling Li, Zhen Mei, Sabrina Racine Brzostek, Gary Rose, Corinna Schultz, Alexa Siddon, Christine Sillings, John Mark Sloan, Amy Soni, Don Stevens, Charlotte Story, James Szymanski, Clifford Takemoto, Alexis Thompson, Rahma Warsame, Angela Weyand, Samuel Wilson, Nibal Zaghloul, Yadashe Belay, Aliza Fink, Patricia Frustace, Jamie Tyson, Nathalie Van Havre, Maureen Okam Achebe

Blood (2025) 146 (Supplement 1): 1074.

https://doi.org/10.1182/blood-2025-1074

Published: 2025

Journal Articles

Modeling germline DDX41 and/or CHEK2 mutations using patient-derived bone marrow Organoids

Inci Aydemir, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Pan Wang, Laya Soleimani, Madina Sukhanova, Lucy Godley, Peng Ji

Blood (2025) 146 (Supplement 1): 1444.

https://doi.org/10.1182/blood-2025-1444

Published: 2025

Journal Articles

Bone Marrow Microenvironment Dictates the Progression of Clonal Hematopoiesis through Stromal-Macrophage Cell-Cell Interactions

Kehan Ren, Ermin Li, Xu Han, Pan Wang, Inci Aydemir, Kara Tao, Madina Sukhanova, Peng Ji

Blood (2024) 144 (Supplement 1): 821.

https://doi.org/10.1182/blood-2024-211058

Published: 2024

Journal Articles

Germline DDX41 Mutations Disrupt Hematopoiesis and Microenvironment in Patient-Derived Bone Marrow Organoids

Inci Aydemir, Xu Han, Honghao Bi, Ermin Li, Kehan Ren, Pan Wang, Madina Sukhanova, Lucy Godley, Peng Ji

Blood (2024) 144 (Supplement 1): 4093.

https://doi.org/10.1182/blood-2024-211026

Published: 2024

Journal Articles

ICAM4 Mediates Human Erythroid Centered Island Formation

Xu Han, Kehan Ren, Pan Wang, Honghao Bi, Inci Aydemir, Ermin Li, Peng Ji

Blood (2024) 144 (Supplement 1): 2451.

https://doi.org/10.1182/blood-2024-204183

Published: 2024

Journal Articles

PPIL2 Is a Target of the JAK2-STAT5 Pathway and Mediates p53 Polyubiquitination and Degradation

Pan Wang, Xu Han, Kehan Ren, Ermin Li, Honghao Bi, Inci Aydemir, Peng Ji

Blood (2023) 142 (Supplement 1): 4515.

https://doi.org/10.1182/blood-2023-177677

Published: 2023

Journal Articles

Rapid Degradation of mDia2 Protein during Terminal Erythropoiesis Via an In Vivo Aid System: An Alternative Approach for Loss-of-Function Studies

Kehan Ren, Zongjun Xia, Ermin Li, Xu Han, Peng Ji

Blood (2023) 142 (Supplement 1): 2443.

https://doi.org/10.1182/blood-2023-178268

Published: 2023

Journal Articles

Spatial Mapping Reveals Distinct Erythroid Niches in Mice and Humans during Development and Stress

Xu Han, Kehan Ren, Pan Wang, Honghao Bi, Inci Aydemir, Ermin Li, Peng Ji

Blood (2023) 142 (Supplement 1): 140.

https://doi.org/10.1182/blood-2023-181272

Published: 2023

Journal Articles

DDX41 Dissolves G-Quadruplexes to Maintain Erythroid Genomic Integrity and Prevent Genome DNA Leakage-Induced Cgas Activation

Honghao Bi, Pan Wang, Wen Wang, Kehan Ren, Elizabeth Bartom, Xu Han, Ermin Li, Peng Ji

Blood (2023) 142 (Supplement 1): 949.

https://doi.org/10.1182/blood-2023-177765

Published: 2023

Journal Articles

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation

Guillaume Courbon, Jane Joy Thomas, Marta Martinez-Calle, Xueyan Wang, Jadeah Spindler, John Von Drasek, Bridget Hunt-Tobey, Rupal Mehta, Tamara Isakova, Wenhan Chang, John W. M. Creemers, Peng Ji, Aline Martin, Valentin David

Blood (2023) 142 (1): 106–118.

https://doi.org/10.1182/blood.2022018475

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Blood (2023) 141 (3): 244–259.

https://doi.org/10.1182/blood.2022016580

Published: 2023

Includes: Supplemental data

Journal Articles

Serum Response Factor Is Critical for Terminal Erythropoiesis

Kehan Ren, Ermin Li, Zongjun Xia, Peng Ji

Blood (2022) 140 (Supplement 1): 5301.

https://doi.org/10.1182/blood-2022-160169

Published: 2022

Journal Articles

Gasdermin D Mediates Inflammation-Driven Pathogenesis of the Myelodysplastic Syndromes

Kehan Ren, Yang Mei, Yijie Liu, Xu Han, Ermin Li, Honghao Bi, Peng Ji

Blood (2021) 138 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2021-149340

Published: 2021

Journal Articles

Nuclear Opening and Histone Release Are Essential for Nuclear but Not Chromatin Condensation during Terminal Erythropoiesis

Honghao Bi, Yijie Liu, Dongmei Wang, Ye Hou, Yue Feng, Peng Ji

Blood (2021) 138 (Supplement 1): 287.

https://doi.org/10.1182/blood-2021-150794

Published: 2021

Journal Articles

Membrane skeleton modulates erythroid proteome remodeling and organelle clearance

Yijie Liu, Yang Mei, Xu Han, Farida V. Korobova, Miguel A. Prado, Jing Yang, Zhangli Peng, Joao A. Paulo, Steven P. Gygi, Daniel Finley, Peng Ji

Blood (2021) 137 (3): 398–409.

https://doi.org/10.1182/blood.2020006673

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

IL-6 Deficiency Reverses Leukemic Transformation in an MDS Mouse Model

Yang Mei, PhD, Yijie Liu, PhD, Xu Han, PhD, Jing Yang, PhD, Peng Ji, MDPhD

Blood (2020) 136 (Supplement 1): 36.

https://doi.org/10.1182/blood-2020-137026

Published: 2020

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Plek2 as a novel downstream effector of p53: Targeting Plek2 ameliorates disease progression in p53-deficient myeloid malignancies

Spatial transcriptomic dissection of the myeloproliferative neoplasm niche uncovers mutant clone interactions and microenvironmental rewiring

DHODH-driven pyrimidine metabolism is a targetable vulnerability in myeloproliferative neoplasms

Inflammatory remodeling and CD4+ T cell expansion in TET2-mutated myeloid disorders

Multicenter assessment of absolute neutrophil counts (ANC) and white blood cell counts (WBC) in healthy participants with the erythrocyte duffy null phenotype or genotype

Modeling germline DDX41 and/or CHEK2 mutations using patient-derived bone marrow Organoids

Bone Marrow Microenvironment Dictates the Progression of Clonal Hematopoiesis through Stromal-Macrophage Cell-Cell Interactions

Germline DDX41 Mutations Disrupt Hematopoiesis and Microenvironment in Patient-Derived Bone Marrow Organoids

ICAM4 Mediates Human Erythroid Centered Island Formation

PPIL2 Is a Target of the JAK2-STAT5 Pathway and Mediates p53 Polyubiquitination and Degradation

Rapid Degradation of mDia2 Protein during Terminal Erythropoiesis Via an In Vivo Aid System: An Alternative Approach for Loss-of-Function Studies

Spatial Mapping Reveals Distinct Erythroid Niches in Mice and Humans during Development and Stress

DDX41 Dissolves G-Quadruplexes to Maintain Erythroid Genomic Integrity and Prevent Genome DNA Leakage-Induced Cgas Activation

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Serum Response Factor Is Critical for Terminal Erythropoiesis

Gasdermin D Mediates Inflammation-Driven Pathogenesis of the Myelodysplastic Syndromes

Nuclear Opening and Histone Release Are Essential for Nuclear but Not Chromatin Condensation during Terminal Erythropoiesis

Membrane skeleton modulates erythroid proteome remodeling and organelle clearance

IL-6 Deficiency Reverses Leukemic Transformation in an MDS Mouse Model

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American Society of Hematology

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