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Roddy O'Connor
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Journal Articles

Single-day non-activated IL-18-armed CAR T cells with enhanced persistence and durable efficacy

Free
Joseph Durgin, Shin Seo, Shadab Kazmi, Bakir Valentic, Chloe Leff, Xioling Jin, Feng Shen, Nandana Mukherjee, Ashwin Sannecy, Gabriela Plesa, Khatuna Gabunia, John Scholler, Saar Gill, Roddy O'Connor, Carl June, Saba Ghassemi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4187.
https://doi.org/10.1182/blood-2025-4187
Published: 2025
Journal Articles

Glucose transporter 5 enhances CAR-T cell metabolic function and serial killing

Free
Bakir Valentic, Andre Kelly, Feng Shen, John Scholler, Max Shestov, Nathaniel Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy O'Connor
Journal: Blood
Blood (2025) 146 (Supplement 1): 2351.
https://doi.org/10.1182/blood-2025-2351
Published: 2025
Journal Articles

Monocarboxylate transporter 1 deficient donor T cells rewire metabolism and ameliorate aGVHD lethality

Free
Eun Ko, Asim Saha, Cameron McDonald-Hyman, Sujeong Jin, Yujie Zhao, Keli Hippen, Jeffrey Rathmell, Greg Delgoffe, Peter Crawford, Roddy O'Connor, Bruce Blazar
Journal: Blood
Blood (2025) 146 (Supplement 1): 5867.
https://doi.org/10.1182/blood-2025-5867
Published: 2025
Journal Articles

Metabolic conditioning for enhanced CAR T cell function

Free
Yufan Zhou, Andre Kelly, Tyler Quarton, Bakir Valentic, Andrew Frisch, Zhiyang Gan, Alexander Shestov, Noah Ford, Jai Patel, Shimin Liu, Khatuna Gabunia, Joseph Durgin, Xiangyi Fang, Max Wadley, Sophie Trefely, Lindsay Pino, Francisca deLuna Vitorino, Dawei Liu, Eliana Von Krusenstiem, Natalia Romero, John Lawson, Benjamin Garcia, Nathaniel Snyder, Saba Ghassemi, John Scholler, Carl June, Roddy O'Connor
Journal: Blood
Blood (2025) 146 (Supplement 1): 4127.
https://doi.org/10.1182/blood-2025-4127
Published: 2025
Journal Articles

Physiologix™ Serum Replacement and NB-ROC™ T Cell Culture Media Combination Shows Enhanced T-Cell Transduction Efficiency for CAR-T Therapy

Free
Asma Ayari, Diana Maradze, Nanami Kadota, Roddy O'Connor
Journal: Blood
Blood (2022) 140 (Supplement 1): 12694.
https://doi.org/10.1182/blood-2022-171033
Published: 2022
Journal Articles

Signaling Domain of Chimeric Antigen Receptors Can Reprogram T Cells

Free
Omkar Uday Kawalekar, MS, BS, Roddy O'Connor, PhD, Sonia Guedan, PhD, Joseph Fraietta, PhD, Avery D. Posey, PhD, John Scholler, Michael C Milone, MD PhD, Carl H. June, MD
Journal: Blood
Blood (2014) 124 (21): 551.
https://doi.org/10.1182/blood.V124.21.551.551
Published: 2014