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Journal Articles

Mim8 prophylaxis in adults and adolescents with hemophilia A: 52-week efficacy and safety outcomes from the phase 3 FRONTIER2 study

Steven Lentz, Aby Abraham, Cihan Ay, Anthony Chan, Víctor Jiménez-Yuste, Johannes Oldenburg, Maria Elisa Mancuso, Johnny Mahlangu, Tadashi Matsushita, Lize van Vulpen, Renchi Yang, Amalie Rhode Høgh Nielsen, Ilgiz Rakhmatullin, Pratima Chowdary

Blood (2025) 146 (Supplement 1): 537.

https://doi.org/10.1182/blood-2025-537

Published: 2025

Journal Articles

Low dose AAV8-FVIII gene therapy on Chinese severe Hemophilia A patients with sustainable efficacy and safety

Wei Liu, Xinyue Dai, Feng Xue, Chen Yunfei, Xiaofan Liu, Rongfeng Fu, Renchi Yang, Lei Zhang

Blood (2025) 146 (Supplement 1): 4317.

https://doi.org/10.1182/blood-2025-4317

Published: 2025

Journal Articles

Proteomic analysis identifying biomarkers in the progression from essential thrombocythemia to post-essential thrombocythemia myelofibrosis: A retrospective cohort study

Mingyu Jin, Sun Ting, Renchi Yang, Lei Zhang

Blood (2025) 146 (Supplement 1): 1986.

https://doi.org/10.1182/blood-2025-1986

Published: 2025

Journal Articles

Trial in progress: Study design of a randomized, phase 3 trial evaluating the efficacy and safety of mezagitamab (TAK-079) compared with placebo in adults with chronic primary immune thrombocytopenia

David Kuter, Chen Yunfei, Nicola Cooper, Waleed Ghanima, Hisashi Kato, Yoshiaki Tomiyama, Raymond Wong, Renchi Yang, Cheryl Li, Emily Skelton, Scarlett Wang, Donald Yee, Parth Patwari

Blood (2025) 146 (Supplement 1): 3049.

https://doi.org/10.1182/blood-2025-3049

Published: 2025

Journal Articles

Phase 3 ESLIM-01 study: Final analysis of efficacy and safety of long-term treatment with sovleplenib in adults with chronic primary immune thrombocytopenia

Blood (2025) 146 (Supplement 1): 843.

https://doi.org/10.1182/blood-2025-843

Published: 2025

Journal Articles

A proteomics-driven machine learning tool for distinguishing ET from pre-PMF

Qing Wen, Sun Ting, Renchi Yang, Chen Yunfei, Lei Zhang

Blood (2025) 146 (Supplement 1): 1973.

https://doi.org/10.1182/blood-2025-1973

Published: 2025

Journal Articles

Long-term outcomes with emicizumab prophylaxis in patients with hemophilia a in China

Blood (2025) 146 (Supplement 1): 1287.

https://doi.org/10.1182/blood-2025-1287

Published: 2025

Journal Articles

Real-world clinical trial of hetrombopag (TPO-RA) in the treatment of primary immune thrombocytopenia (ITP)

Chen Yunfei, Sun Ting, Yanmei Xu, Feng Xue, Xiaofan Liu, Wei Liu, Rongfeng Fu, Mankai Ju, Wenjing Gu, Xinyue Dai, Huan Dong, Renchi Yang, Lei Zhang

Blood (2025) 146 (Supplement 1): 4813.

https://doi.org/10.1182/blood-2025-4813

Published: 2025

Journal Articles

Hetrombopag for patients with persistent primary immune thrombocytopenia: A post-hoc analysis of a multicenter, randomized phase Ⅲ Trial

Blood (2025) 146 (Supplement 1): 4812.

https://doi.org/10.1182/blood-2025-4812

Published: 2025

Journal Articles

Marstacimab prophylaxis in hemophilia A/B without inhibitors: results from the phase 3 BASIS trial

Davide Matino, Andrew Palladino, Carrie Turich Taylor, Eunhee Hwang, Sangeeta Raje, Satyaprakash Nayak, Regina McDonald, Suchitra S. Acharya, Johnny Mahlangu, Victor Jiménez-Yuste, Nirmalkumar Choraria, Renchi Yang, Chi-kong Li, Murtadha Al-Khabori, Yasser Wali, Javier Morales Adrián, Young-Shil Park, O. Bülent Zülfikar, John Teeter

Blood (2025) 146 (14): 1654–1663.

https://doi.org/10.1182/blood.2024027468

Published: 2025

Includes: Supplemental data

Journal Articles

Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy

Wei Liu, Xiaolei Pei, Bingqi Xu, Xinyue Dai, Feng Xue, Linging Chen, Yuhua Wang, Yunfei Chen, Xiaofan Liu, Rongfeng Fu, Wentian Wang, Ying Chi, Huiyuan Li, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 3583.

https://doi.org/10.1182/blood-2024-199915

Published: 2024

Journal Articles

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Feng Xue, Mankai Ju, Tienan Zhu, ZePing Zhou, Jing Sun, Linhua Yang, Zhenyu Yan, Hu Zhou, Xin Du, Changcheng Zheng, Xia Wu, Xiao Xiao, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 3582.

https://doi.org/10.1182/blood-2024-204715

Published: 2024

Journal Articles

Demographics and Clinical Profile of Hemophilia Patients in China - Results from a Cross-Sectional, Community-Based Survey

Feng Xue, Chun Chang, Karina Chin Po Hsu, Jing Sun, Xinsheng Zhang, Shujie Wang, Jingsheng Wu, Rong Chen, Danni Shi, Felix Cao, Renchi Yang

Blood (2024) 144 (Supplement 1): 5485.

https://doi.org/10.1182/blood-2024-207783

Published: 2024

Journal Articles

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Wei Liu, Hu Zhou, Ruibin Huang, Xin Du, ZePing Zhou, Changcheng Zheng, Shifeng Lou, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 1213.

https://doi.org/10.1182/blood-2024-199149

Published: 2024

Journal Articles

Artificial Intelligence-Based Quantitative Bone Marrow Pathology Analysis for Myeloproliferative Neoplasms

Dandan Yu, Hong-Ju Zhang, Yanyan Song, Yuan Tao, Fengyuan Zhou, Ziyi Wang, Rongfeng Fu, Ting Sun, Huan Dong, Wenjing Gu, Renchi Yang, Zhijian Xiao, Qi Sun, Lei Zhang

Blood (2024) 144 (Supplement 1): 3182.

https://doi.org/10.1182/blood-2024-201265

Published: 2024

Journal Articles

Long-Term Sovleplenib Treatment of Adults with Primary Immune Thrombocytopenia in China

Blood (2024) 144 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2024-204447

Published: 2024

Journal Articles

Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia

Yu Yang, Huiyuan Li, Xiaofan Liu, Hong Wang, Lei Zhang, Renchi Yang

Blood (2024) 144 (Supplement 1): 2553.

https://doi.org/10.1182/blood-2024-203209

Published: 2024

Journal Articles

A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia

Rongfeng Fu, Xiaofan Liu, Xinmiao Qu, Feng Xue, Wei Liu, Yunfei Chen, Ting Sun, Mankai Ju, Huan Dong, Wenjing Gu, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 5438.

https://doi.org/10.1182/blood-2024-204932

Published: 2024

Journal Articles

A Novel F12 Gene Pathogenic Mutation Identified in a Consanguineous Pedigree with Clustered Thrombotic and Pulmonary Disease

Xinmiao Qu, Xiaofan Liu, Rongfeng Fu, Yujiao Jia, Yuhua Wang, Feng Xue, Wei Liu, Yunfei Chen, Ting Sun, Mankai Ju, Huan Dong, Wenjing Gu, Xinyue Dai, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 5558.

https://doi.org/10.1182/blood-2024-202375

Published: 2024

Journal Articles

Machine Learning Analysis Was Conducted to Construct a Novel Model for Modulating the Clinical Manifestations and Predicting the Response to Glucocorticoids in Immune Thrombocytopenia

Jing Zhang, Jia Chen, Renchi Yang, Lei Zhang

Blood (2024) 144 (Supplement 1): 2570.

https://doi.org/10.1182/blood-2024-203542

Published: 2024

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Mim8 prophylaxis in adults and adolescents with hemophilia A: 52-week efficacy and safety outcomes from the phase 3 FRONTIER2 study

Low dose AAV8-FVIII gene therapy on Chinese severe Hemophilia A patients with sustainable efficacy and safety

Proteomic analysis identifying biomarkers in the progression from essential thrombocythemia to post-essential thrombocythemia myelofibrosis: A retrospective cohort study

Trial in progress: Study design of a randomized, phase 3 trial evaluating the efficacy and safety of mezagitamab (TAK-079) compared with placebo in adults with chronic primary immune thrombocytopenia

Phase 3 ESLIM-01 study: Final analysis of efficacy and safety of long-term treatment with sovleplenib in adults with chronic primary immune thrombocytopenia

A proteomics-driven machine learning tool for distinguishing ET from pre-PMF

Long-term outcomes with emicizumab prophylaxis in patients with hemophilia a in China

Real-world clinical trial of hetrombopag (TPO-RA) in the treatment of primary immune thrombocytopenia (ITP)

Hetrombopag for patients with persistent primary immune thrombocytopenia: A post-hoc analysis of a multicenter, randomized phase Ⅲ Trial

Marstacimab prophylaxis in hemophilia A/B without inhibitors: results from the phase 3 BASIS trial

Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy

Efficacy and Safety of an Engineered, Liver-Tropic Adeno-Associated Virus Vector Expressing Factor IX Padua Administered with Prophylactic Glucocorticoids in Patients with Hemophilia B: A Multi-Center, Single-Arm, Phase 3 Trial

Demographics and Clinical Profile of Hemophilia Patients in China - Results from a Cross-Sectional, Community-Based Survey

A Specific Coagulation Factor X Activator for on-Demand Treatment in Hemophilia with Inhibitors

Artificial Intelligence-Based Quantitative Bone Marrow Pathology Analysis for Myeloproliferative Neoplasms

Long-Term Sovleplenib Treatment of Adults with Primary Immune Thrombocytopenia in China

Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia

A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia

A Novel F12 Gene Pathogenic Mutation Identified in a Consanguineous Pedigree with Clustered Thrombotic and Pulmonary Disease

Machine Learning Analysis Was Conducted to Construct a Novel Model for Modulating the Clinical Manifestations and Predicting the Response to Glucocorticoids in Immune Thrombocytopenia

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