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Regis Costello
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Journal Articles

Odyssey: A first-in-human study of the aldehyde dehydrogenase (ALDH) inhibitor abd-3001 in patients with refractory/relapsed acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS)

Free
Mael Heiblig, Lina Benajiba, Julien Colle, Sandrine Loron, Juliette Soret, Rafael Daltro De Oliveira, Geoffroy Venton, Marie-Virginie Larcher, Laure Farnault, Mühübe Yazir, Mileidys Perez, Ismail Ceylan, Guillaume Martin, Annick Pelletier, Jean-Jacques Kiladjian, Régis Costello
Journal: Blood
Blood (2025) 146 (Supplement 1): 3421.
https://doi.org/10.1182/blood-2025-3421
Published: 2025
Journal Articles

Anthracyclines induce epigenetic changes in ALDH1A that promote chemoresistance in AML, revealing a potential treatment strategy co-targeting ALDH1A inhibition with hypomethylating agents

Free
Mehak Shaikh, Francesco Leonetti, Mühübe Yazir, Celine Baier, Miroslava Adamcova, Andrada Constantineascu, Iris Manosalva, Regis Costello, Guillaume Martin, Salvatore Spicuglia, Meritxell Alberich-Jorda, Mileidys Perez
Journal: Blood
Blood (2025) 146 (Supplement 1): 214.
https://doi.org/10.1182/blood-2025-214
Published: 2025
Journal Articles

Epcoritamab + GemOx achieves durable >2-year remissions in relapsed/refractory (R/R) 2L+ diffuse large B-cell lymphoma (DLBCL): Long-term data reinforce clinical potential of the regimen across a diverse patient population

Free
Joshua Brody, David Belada, Daniel Morillo, Régis Costello, Marek Trneny, Sven de Vos, Gerardo Musuraca, Umberto Vitolo, David Lewis, Jacob Christensen, Marcel Nijland, Tony Jiang, Kubra Karagoz, Andrew J. Steele, Jennifer Marek, Liwei Wang, Malene Risum, Raul Cordoba, Judit Jørgensen
Journal: Blood
Blood (2025) 146 (Supplement 1): 3736.
https://doi.org/10.1182/blood-2025-3736
Published: 2025
Journal Articles

Epcoritamab plus GemOx in transplant-ineligible relapsed/refractory DLBCL: results from the EPCORE NHL-2 trial

Open Access
Clinical Trials & Observations
Joshua D. Brody, Judit Jørgensen, David Belada, Régis Costello, Marek Trněný, Umberto Vitolo, David John Lewis, Yasmin H. Karimi, Anna Sureda, Marc André, Björn E. Wahlin, Pieternella J. Lugtenburg, Tony Jiang, Kubra Karagoz, Andrew J. Steele, Aqeel Abbas, Liwei Wang, Malene Risum, Raul Cordoba
Journal: Blood
Blood (2025) 145 (15): 1621–1631.
https://doi.org/10.1182/blood.2024026830
Published: 2025
Includes: Supplemental data
Journal Articles

Open-Label Phase 2 Study Results of FS118, a LAG-3/PD-L1 Bispecific Antibody, in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Free
Jean-Marie Michot, Abhay Patki, Marina Maglakelidze, Regis Costello, Martin Donchev, Vincent Ribrag, Igori Vinogradov
Journal: Blood
Blood (2024) 144 (Supplement 1): 1731.
https://doi.org/10.1182/blood-2024-202538
Published: 2024
Journal Articles

Odyssey: A First-in-Human Study of the Aldehyde Dehydrogenase (ALDH) Inhibitor Abd-3001 in Patients with Refractory/Relapsed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)

Free
Lina Benajiba, Julien Colle, Mael Heiblig, Sandrine Loron, Juliette Soret-Dulphy, Paul Berchard, Mühübe Yazir, Laurent Basset, Geoffroy Venton, Marie-Virginie Larcher, Rafael Daltro De Oliveira, Gaëlle Fossard, Guillaume Martin, Mileidys Perez, Ismael Ceylan, Annick Pelletier, Jean-Jacques Kiladjian, Régis Costello
Journal: Blood
Blood (2024) 144 (Supplement 1): 6001.
https://doi.org/10.1182/blood-2024-204998
Published: 2024
Journal Articles

Stability Assessment of Fresh or Cryopreserved Whole Blood and Bone Marrow Samples from AML and B-ALL Patients to Monitor CD123 Receptor and Immune Cells Subsets

Free
Jacqueline Courta, Marielle Balzano, Wilfried Passe-Coutrin, Margaux Lagier, Karine Grivel, Daniele Boulay Moine, Drifa Beroual, Anne-Laure Bauchet, Geoffroy Venton, Regis Costello, Maxime Moulard
Journal: Blood
Blood (2023) 142 (Supplement 1): 6032.
https://doi.org/10.1182/blood-2023-179207
Published: 2023
Journal Articles

Splenomegaly Study (SMS): Which Etiologies for Unexplained Splenomegalies?

Free
Guillaume Denis, Louis Terriou, Thomas Séné, Regis Costello, Martin Michaud, Claudia Hellé, Audrey Lagadec, Frédéric Bauduer, Laurence Sanhes, Christian Rose, Geoffrey Urbanski, Marc G. Berger
Journal: Blood
Blood (2021) 138 (Supplement 1): 2991.
https://doi.org/10.1182/blood-2021-148322
Published: 2021
Journal Articles

New Detection Method of V617F JAK2 Mutation; Its Use in a Clinical Setting.

Free
Delphine Chabas, Nathalie Beaufils, Gerard Sebahoun, Regis Costello, J. Weiller, Jean-Robert Harle, Jean Gabert
Journal: Blood
Blood (2006) 108 (11): 4889.
https://doi.org/10.1182/blood.V108.11.4889.4889
Published: 2006