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Ophelia Yin
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Journal Articles

Efficacy and safety of mitapivat in pediatric patients with pyruvate kinase deficiency who are not regularly transfused: Results from the Phase 3, global, randomized, double-blind, placebo-controlled ACTIVATE-Kids trial

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Satheesh Chonat, Rachael Grace, Kathryn Dickerson, Oliver Andres, Marije Bartels, Vanessa Beynon, Jenny Despotovic, Bertil Glader, Yoann Huguenin, Janet Kwiatkowski, Erin Laflam, Leonardo Rivadeneyra, Bryan McGee, Ophelia Yin, Thais Murciano Carrillo, Yves Pastore, Jennifer Rothman, Patrick Tyler, Emily Xu, Raffaele Renella, Julian Sevilla
Journal: Blood
Blood (2025) 146 (Supplement 1): 4654.
https://doi.org/10.1182/blood-2025-4654
Published: 2025
Journal Articles

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

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Modupe Idowu, Lucas Otieno, Bogdan Dumitriu, Clarisse LC Lobo, Swee Lay Thein, Biree Andemariam, Obiageli E Nnodu, Adlette Inati, Alexander K Glaros, Sara Teresinha Olalla Saad, Pablo Bartolucci, Raffaella Colombatti, Ali T Taher, Miguel R Abboud, Abdulafeez Oluyadi, Varsha Iyer, Ophelia Yin, Susan Morris, Amber M Yates, Hui Shao, Spurthi Patil, Rolandas Urbstonaitis, Ahmar U Zaidi, Wally R Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 271.
https://doi.org/10.1182/blood-2023-187033
Published: 2023
Journal Articles

A Phase 2a/2b Multicenter Study of AG-946 in Patients with Anemia Due to Lower-Risk Myelodysplastic Syndromes

Free
Hanny Al-Samkari, Pierre Fenaux, Mikkael A. Sekeres, Eytan Stein, David A. Sallman, Andrew M. Brunner, Xiaoshu D. Gurov, Ophelia Yin, Meghan Frisbie, James Xiao, Joy Bhatia, Vanessa Beynon, Megan Wind-Rotolo, Melissa Dibacco, Uwe Platzbecker
Journal: Blood
Blood (2022) 140 (Supplement 1): 4076–4078.
https://doi.org/10.1182/blood-2022-168907
Published: 2022
Journal Articles

Exposure-Response of Quizartinib Efficacy in Patients with Relapsed/Refractory AML

Free
Dongwoo Kang, PhD, Julie Passarell, MA, Malaz A Abutarif, PhD, Jeanne Mendell, PhD MPH, Ophelia Yin, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1263.
https://doi.org/10.1182/blood-2019-122582
Published: 2019
Journal Articles

Nilotinib Exposure-Response Analysis In Patients with Imatinib-Resistant or -Intolerant Chronic Myeloid Leukemia (CML)

Free
Francis J. Giles, MB, MD, FRCPI, FRCPath, Ophelia Yin, PhD, FCP, Yen Lin Chia, PhD, Philipp D. le Coutre, MD, Richard C. Woodman, MD, Oliver G. Ottmann, MD, Michele Baccarani, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2010) 116 (21): 890.
https://doi.org/10.1182/blood.V116.21.890.890
Published: 2010
Journal Articles

Comparative in Vitro Cellular Data Alone Is Insufficient to Predict Clinical Responses and Guide Choice of BCR-ABL Inhibitor to Treat Imatinib-Resistant Chronic Myeloid Leukemia.

Free
Pierre Laneuville, MD, FRCPC, Clifford DiLea, PharmD, Jürgen Mestan, Ophelia Yin, PhD, FCP, Richard C. Woodman, MD, Paul Manley, PhD
Journal: Blood
Blood (2009) 114 (22): 510.
https://doi.org/10.1182/blood.V114.22.510.510
Published: 2009
Journal Articles

The KIT Tyrosine Kinase Inhibitor Midostaurine (PKC412) Exhibits a High Response Rate in Aggressive Systemic Mastocytosis (ASM): Interim Results of a Phase II Trial.

Free
Jason Gotlib, Tracy I. George, Chris Corless, Andrea Linder, Alisa Ruddell, Cem Akin, Daniel J. DeAngelo, Ilana Kepten, Carlo Lanza, Heidrun Heinemann, Ophelia Yin, Neil Gallagher, Tim Graubert
Journal: Blood
Blood (2007) 110 (11): 3536.
https://doi.org/10.1182/blood.V110.11.3536.3536
Published: 2007