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N. Connor Payne
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Journal Articles

Inhibition of prolyl-tRNA synthetase sensitizes acute myeloid leukemia to venetoclax through bmf-mediated apoptosis

Free
Yuri Okazoe-Hirakawa, keiji Kurata, Hidetomo Takakura, Sakuya Matsumoto, Yohei Funakoshi, Kimikazu Yakushijin, N Connor Payne, Ralph Mazitschek, Hironobu Minami
Journal: Blood
Blood (2025) 146 (Supplement 1): 1454.
https://doi.org/10.1182/blood-2025-1454
Published: 2025
Journal Articles

Prolyl-tRNA synthetase inhibition disrupts oncogenic translation in T-cell acute lymphoblastic leukemia

Free
Valerio Ciaurro, Abdul Khalique, Priyanshu Srivastava, Yu Zhou, Paul Hauser, N. Connor Payne, Marian Kalocsay, Ralph Mazitschek, Palaniraja Thandapani
Journal: Blood
Blood (2025) 146 (Supplement 1): 6780.
https://doi.org/10.1182/blood-2025-6780
Published: 2025
Journal Articles

Pharmacological Targeting of IRF4 As a Therapeutic Strategy for Multiple Myeloma

Free
Michael P. Agius, Laura Hevenor, N Connor Payne, Qi Liu, Hyuk-Soo Seo, Romanos Sklavenitis-Pistofidis, Daniel Heilpern-Mallory, Puspalata Bashyal, Michelle P. Aranha, Elizabeth D. Lightbody, Ralph Mazitschek, Sirano Dhe-Paganon, Jun Qi, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 155.
https://doi.org/10.1182/blood-2024-203381
Published: 2024
Journal Articles

Targeting Proline Trna Biogenesis for Treatment of T Cell Acute

Free
Valerio Ciaurro, Priyanshu Srivastava, Abdul Khalique, Jared Brottem, N Connor Payne, Ralph Mazitschek, Palaniraja Thandapani
Journal: Blood
Blood (2024) 144 (Supplement 1): 5835.
https://doi.org/10.1182/blood-2024-200359
Published: 2024
Journal Articles

Discovery of First-in-Class Small Molecule Inhibitors of the IRF4-PU.1/Spi-B Interaction

Free
Mike P. Agius, Laura Hevenor, N Connor Payne, Ralph Mazitschek, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jun Qi, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 3635.
https://doi.org/10.1182/blood-2023-186864
Published: 2023
Journal Articles

Discovery of Prolyl-tRNA Synthetase As a Novel Target in Multiple Myeloma

Free
Keiji Kurata, Anna-James Bott, Teru Hideshima, James Dunford, Filiz Senbabaoglu, Catrine Johansson, Adam Cribbs, Martin Philpott, Sarah Gooding, Leona Yamamoto, Mehmet K. Samur, Yu-Tzu Tai, Mark A Tye, N Connor Payne, Patrick Hagner, Karthik Ramasamy, Anjan Thakurta, Ralph Mazitschek, Udo Oppermann, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 890.
https://doi.org/10.1182/blood-2021-148536
Published: 2021