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Monzr M. AL Malki
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Journal Articles

Intensive chemotherapy bridging to allogeneic hematopoietic cell transplant in relapsed or refractory Acute Myeloid Leukemia

Free
Paul Koller, Jose Tinajero, Dat Ngo, Dongyun Yang, Ahmed Aribi, Ibrahim Aldoss, Vinod Pullarkat, Amandeep Salhotra, Eileen Smith, Anthony Selwyn Stein, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Monzr M. Al Malki
Journal: Blood
Blood (2025) 146 (Supplement 1): 3411.
https://doi.org/10.1182/blood-2025-3411
Published: 2025
Journal Articles

Mismatching of unrelated donors beyond a single HLA-locus does not adversely impact outcomes at one year following transplantation: Results from the NMDP sponsored ACCESS study

Free
Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Sarah Smith, Erin Leckrone, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Brian Shaffer, Dipenkumar Modi, Farhad Khimani, Mahasweta Gooptu, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez
Journal: Blood
Blood (2025) 146 (Supplement 1): 936.
https://doi.org/10.1182/blood-2025-936
Published: 2025
Journal Articles

Post-transplant cyclophosphamide-based graft-verses-host disease (GVHD) prophylaxis is associated with a low incidence of fibrotic chronic GVHD after allogeneic hematopoietic cell transplantation across diverse donor types

Free
Klara Kim, Dat Ngo, Jose Tinajero, Dongyun Yang, Haoyue Shan, Karamjeet Sandhu, Haris Ali, Salman Otoukesh, Idoroenyi Amanam, Shukaib Arslan, Vaibhav Agrawal, Sunmin Park, Ryotaro Nakamura, Monzr M. Al Malki, Amandeep Salhotra
Journal: Blood
Blood (2025) 146 (Supplement 1): 935.
https://doi.org/10.1182/blood-2025-935
Published: 2025
Journal Articles

A phase 1/2, first-in-human, multicenter, open-label trial evaluating the safety, tolerability, and antileukemic activity of Debio 1562M in patients with recurrent refractory acute myeloid leukemia (AML)

Free
Naval Daver, Andrew Sochacki, Monzr M. Al Malki, Eunice Wang, Marianna Muller, Anne Bellon, Sandrine Micallef, David Sallman, Karilyn Larkin
Journal: Blood
Blood (2025) 146 (Supplement 1): 5194.
https://doi.org/10.1182/blood-2025-5194
Published: 2025
Journal Articles

Secondary graft failure after PT-cy: Modeling a candidate risk assignment biomarker based on lymphocyte reconstitution.  Results from the BMT CTN 1801 study.

Free
Kayleigh Ingersoll Omdahl, Steven Siegel, Jiayi Dong, Susan DeWolf, Kyle Hebert, Donna Neuberg, Isabella Schichter, Alexandre Albanese, Paul Keskula, Lorenzo Cagnin, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung Choi, William Clark, Suman Das, Robert Jenq, Richard Jones, John Levine, Brent Logan, Michael Martens, Hemant Murthy, Armin Rashidi, Marcie Riches, Wael Saber, Karamjeet Sandhu, Anthony Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian Shaffer, Andrew Rezvani, Najla El Jurdi, Alison Loren, Mary Horowitz, Javier Bolanos-Meade, Shernan Holtan, Ami Bhatt, Miguel-Angel Perales, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2025-4198
Published: 2025
Journal Articles

TSC-101 eliminates recipient hematopoietic cells and demonstrates potential for improved relapse-free survival in patients with AML, ALL, or MDS undergoing allogeneic HCT: Updated results from the Phase 1 (ALLOHA) trial

Free
Monzr M. Al Malki, Yi-Bin Chen, Tania Jain, Alla Keyzner, Melhem Solh, Uday Popat, Michele Donato, Luis Pineiro, Hugo Fernandez, Saar Gill, Anson Snow, Joseph Uberti, Timothy White, Yun Wang, Cuong Nguyen, Chrystal Louis, Shrikanta Chattopadhyay, Michelle Matzko, Ran Reshef
Journal: Blood
Blood (2025) 146 (Supplement 1): 2391.
https://doi.org/10.1182/blood-2025-2391
Published: 2025
Journal Articles

Prevalence and impact of somatic mutations in patients with aplastic anemia (AA) undergoing allogeneic hematopoietic cell transplantation (HCT): A single center retrospective analysis

Free
Salman Otoukesh, Brian Ball, Dongyun Yang, Ketevan Gendzekhadze, Karamjeet Sandhu, Shukaib Arslan, Amanda Blackmon, Pamela Becker, Firoozeh Sahebi, Anna Pawlowska, Monzr M. Al Malki, Michelle Afkhami, Stephen Forman, Guido Marcucci, Vinod Pullarkat, Raju Pillai, Ryotaro Nakamura
Journal: Blood
Blood (2025) 146 (Supplement 1): 1431.
https://doi.org/10.1182/blood-2025-1431
Published: 2025
Journal Articles

Clearance of RAS pathway mutations prior to allogeneic transplant in Acute Myeloid Leukemia are associated with favorable overall and leukemia free survival

Free
Claire Carlson, Jose Tinajero, Dat Ngo, Huiyan Ma, Sunmin Park, Shukaib Arslan, Amanda Blackmon, Vaibhav Agrawal, Hoda Pourhassan, Salman Otoukesh, Idoroenyi Amanam, Paul Koller, Karamjeet Sandhu, Ahmed Aribi, Ibrahim Aldoss, Andrew Artz, Monzr M. Al Malki, Vinod Pullarkat, Haris Ali, Eileen Smith, Anthony Selwyn Stein, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Pamela Becker, Michelle Afkhami, Brian Ball, Amandeep Salhotra
Journal: Blood
Blood (2025) 146 (Supplement 1): 4305.
https://doi.org/10.1182/blood-2025-4305
Published: 2025
Journal Articles

Acrobat interim results: Alloheme surveillance enables early detection of relapse in post-HCT AML and MDS patients

Free
Monzr M. Al Malki, Corey Cutler, Ronald Sobecks, Iskra Pusic, Nelli Bejanyan, Sagar Patel, Arpita Gandhi, Vamsi Kota, Nabeel Rajeh, Piyanuch Kongtim, Chun-Po Fan, Yangyang Hao, Evgeniya Vaskova, Natali Gulbahce, Ashish Kothari, Nishant Dwivedi, Robert Woodward, Ran Reshef, Stefan Ciurea
Journal: Blood
Blood (2025) 146 (Supplement 1): 4301.
https://doi.org/10.1182/blood-2025-4301
Published: 2025
Journal Articles

Evolutionary divergence of polymorphic HLA residues predicts clinical outcomes after haploidentical stem cell transplantation in patients with AML

Free
Shukaib Arslan, Padma Sri Katikaneni, Kristine Cooper, Emily Geramita, Jing-Zhou Hou, Kathleen Dorritie, James Rossetti, Alison Sehgal, Joseph Franz, Annie Im, Warren Shlomchik, Monzr M. Al Malki, Haris Ali, Geoffrey Shouse, Ketevan Gendzekhadze, Nicole Karras, Anthony Selwyn Stein, Guido Marcucci, Ryotaro Nakamura, Sawa Ito, Kevin Quann
Journal: Blood
Blood (2025) 146 (Supplement 1): 512.
https://doi.org/10.1182/blood-2025-512
Published: 2025
Journal Articles

Results from paradigm - a phase 2 randomized multi-center study comparing azacitidine and venetoclax to conventional induction chemotherapy for newly diagnosed fit adults with acute myeloid leukemia

Free
Amir Fathi, Alexander Perl, Geoffrey Fell, Brian Jonas, Brittany Ragon, Alice Mims, Uma Borate, Gabriel Mannis, Karen Quillen, Max Stahl, Paul Koller, Andrew Artz, Monzr M. Al Malki, Guido Marcucci, Mary Linton Peters, Timothy Graubert, Peter Westervelt, Philip Amrein, Hanno Hock, Andrew Brunner, Gabriela Hobbs, Rupa Narayan, Michelle Lee, Brandon Aubrey, Alyssa Watson, Richard Hao, Shilton Dhaver, Michael Grunwald, Yi-Bin Chen, Andrew Matthews, Christopher Hourigan, Brent Wood, Donna Neuberg, Areej El-Jawahri, Ibrahim Aldoss
Journal: Blood
Blood (2025) 146 (Supplement 1): 6.
https://doi.org/10.1182/blood-2025-6
Published: 2025
Journal Articles

Trials in progress: Design of a registrational Phase 2 trial (ALLOHA) using an external control arm for TSC-101 for prevention of relapse post allogeneic HCT in patients with ALL, AML, or MDS

Free
Monzr M. Al Malki, Yi-Bin Chen, Tania Jain, Alla Keyzner, Melhem Solh, Uday Popat, Michele Donato, Luis Pineiro, Hugo Fernandez, Saar Gill, Anson Snow, Joseph Uberti, Sameem Abedin, Mahasweta Gooptu, Mathew Angelos, Jeremy Pantin, Kwang Woo Ahn, Ramola Bhandarkar, Shrikanta Chattopadhyay, Samantha Jaglowski, Chrystal Louis, Michelle Matzko, Leavitt Morrison, Waleska Pérez, Eugene Poggio, Ran Reshef
Journal: Blood
Blood (2025) 146 (Supplement 1): 2400.
https://doi.org/10.1182/blood-2025-2400
Published: 2025
Journal Articles

A multicenter phase 1 trial evaluating the safety and preliminary efficacy of revumenib as post-transplant maintenance after allogeneic hematopoietic cell transplant in patients with KMT2A-rearranged or NPM1-mutated acute leukemia

Free
Brian Ball, Mahasweta Gooptu, Ling Li, Christopher Hourigan, Sally Mokhtari, Dongyun Yang, Leonardo Farol, Yazeed Samara, Anthony Selwyn Stein, Guido Marcucci, Monzr M. Al Malki, Corey Cutler, Ryotaro Nakamura, Ibrahim Aldoss
Journal: Blood
Blood (2025) 146 (Supplement 1): 5207.
https://doi.org/10.1182/blood-2025-5207
Published: 2025
Journal Articles

Outcomes of allogeneic hematopoietic cell transplant (HCT) in patients with TP53-altered acute leukemia or myelodysplastic syndrome: A retrospective single center analysis

Free
Salman Otoukesh, Amrita Desai, Dongyun Yang, Sally Mokhtari, Brian Ball, Paul Koller, Amanda Blackmon, Shukaib Arslan, Idoroenyi Amanam, Amandeep Salhotra, Karamjeet Sandhu, Ahmed Aribi, Ibrahim Aldoss, Andrew Artz, Haris Ali, Anthony Selwyn Stein, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Michelle Afkhami, Monzr M. Al Malki
Journal: Blood
Blood (2025) 146 (Supplement 1): 2516.
https://doi.org/10.1182/blood-2025-2516
Published: 2025
Journal Articles

Day 7 mount sinai acute GVHD international consortium (MAGIC) algorithm probability predicts GVHD and non-GVHD-related non-relapse mortality in a contemporary cohort of allogeneic transplant patients

Free
Sunmin Park, NI-Chun Tsai, Amanda Blackmon, Vaibhav Agrawal, Brian Ball, Hoda Pourhassan, Salman Otoukesh, Shukaib Arslan, Idoroenyi Amanam, Paul Koller, Ahmed Aribi, Peter Curtin, Ibrahim Aldoss, Andrew Artz, Vinod Pullarkat, Haris Ali, Amandeep Salhotra, Pamela Becker, Ji-Lian Cai, Firoozeh Sahebi, Anna Pawlowska, Yunzu Wang, F. Marc Stewart, Eileen Smith, Anthony Selwyn Stein, Guido Marcucci, Stephen Forman, Dongyun Yang, Monzr M. Al Malki, Ryotaro Nakamura, Karamjeet Sandhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 2464.
https://doi.org/10.1182/blood-2025-2464
Published: 2025
Journal Articles

Anti-inflammatory drug pegtarazimod (RLS-0071) demonstrates clinical improvement in lower gastrointestinal acute graft-versus-host disease (aGvHD) and target engagement of key inflammatory marker myeloperoxidase (MPO)

Free
Robert Zeiser, Hannah Choe, José Antonio Pérez-Simón, Kenji Cunnion, Monzr M. Al Malki
Journal: Blood
Blood (2025) 146 (Supplement 1): 2462.
https://doi.org/10.1182/blood-2025-2462
Published: 2025
Journal Articles

Grade I acute graft-vs-host disease: Treat or not?

Free
Yu Akahoshi, Nikolaos Katsivelos, Ioannis Evangelos Louloudis, Daniela Weber, Francis Ayuk, William Hogan, Yi-Bin Chen, Aaron Etra, Paibel Aguayo-Hiraldo, Chantiya Chanswangphuwana, Hannah Choe, Elizabeth Hexner, Carrie Kitko, Monzr M. Al Malki, Pietro Merli, Timothy Olson, Muna Qayed, Ingrid Vasova, Matthias Woelfl, Janna Baez, Gilbert Eng, Sigrun Gleich, George Morales, Nikolaos Spyrou, Rachel Young, Ryotaro Nakamura, James Ferrara, John Levine
Journal: Blood
Blood (2025) 146 (Supplement 1): 2461.
https://doi.org/10.1182/blood-2025-2461
Published: 2025
Journal Articles

Itacitinib in combination with post-transplant cyclophosphamide and tacrolimus (ICT) as GVHD prophylaxis for reduced intensity matched donor peripheral blood stem cell hematopoietic cell transplantation: Interim analysis

Free
Monzr M. Al Malki, Dongyun Yang, Sally Mokhtari, Anissa Bailey, Pooja Rajeevan, Rhiannon Imbeah, Salman Otoukesh, Brian Ball, Paul Koller, Vaibhav Agrawal, Yazeed Samara, Firoozeh Sahebi, Ibrahim Aldoss, Andrew Artz, Guido Marcucci, Stephen Forman, Ryotaro Nakamura, Haris Ali
Journal: Blood
Blood (2025) 146 (Supplement 1): 2455.
https://doi.org/10.1182/blood-2025-2455
Published: 2025
Journal Articles

Phase II Study of post transplant cyclophosphamide-based graft versus host disease prophylaxis after HLA-mismatched unrelated donor transplantation and reduced intensity conditioning: Results from the NMDP-sponsored access expansion Study

Free
Mahasweta Gooptu, Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Erin Leckrone, Sarah Smith, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Farhad Khimani, Dipenkumar Modi, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez, Brian Shaffer
Journal: Blood
Blood (2025) 146 (Supplement 1): 4232.
https://doi.org/10.1182/blood-2025-4232
Published: 2025
Journal Articles

Total marrow and lymphoid irradiation (TMLI) with fludarabine-melphalan (FM) conditioning for matched donor hematopoietic cell transplant (HCT) in older patients with Relapsed/Refractory (R/R) disease

Free
Monzr M. Al Malki, Susanta Hui, Dongyun Yang, Sally Mokhtari, Hoda Pourhassan, Matthew Mei, Amanda Blackmon, Firoozeh Sahebi, Amandeep Salhotra, Brian Ball, Shukaib Arslan, Salman Otoukesh, Haris Ali, Guido Marcucci, Ryotaro Nakamura, Stephen Forman, Anthony Selwyn Stein, Jeffrey Wong
Journal: Blood
Blood (2025) 146 (Supplement 1): 376.
https://doi.org/10.1182/blood-2025-376
Published: 2025