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Journal Articles

Foreign antigen delivered to CLL B cells via membrane IgD leads to a distinct antigen processing pathway that allows antigen-specific T cell activation that is superior to membrane IgM delivery

Martina Cardillo, Matthew Friedman, Xiao Yan, Anita Kar Yun Ng, Randall Davis, Michael Ryan, Peter Gregersen, Steven Allen, Jonathan Kolitz, Kanti Rai, Paolo Ghia, Nicholas Chiorazzi

Blood (2025) 146 (Supplement 1): 3882.

https://doi.org/10.1182/blood-2025-3882

Published: 2025

Journal Articles

Dynamic crosstalk between CLL cells and lymph node fibroblasts promotes a pro-tumor microenvironment

Yu-Ju Chen, Antonio Ferreira, Kelly Wong, Samantha Stoneking, Angelika Jiang, Anita Kar Yun Ng, Martina Cardillo, Gonzalo Blanco, Xiao Yan, Susan Buhl, Matthew Scharff, Nicholas Chiorazzi, Ivan Maillard, Jon Aster, Shih-Shih Chen

Blood (2025) 146 (Supplement 1): 241.

https://doi.org/10.1182/blood-2025-241

Published: 2025

Journal Articles

Eradication of the CLECL1+ CLL Subset That Is Prone to Carrying Novel Genomic Mutations and Promoting a Pro-Tumor Microenvironment By a Series of New Monoclonal Antibodies Reactive with Distinct Target Epitopes

Shih-Shih Chen, Susan Buhl, Anita Kar Yun Ng, Laila Schipper, Bianca Cinquemani, Nikhil Trepeta, Martina Cardillo, Gonzalo Blanco, Kelly Wong, Yu-Ju Chen, Xiao J. Yan, Matthew Scharff, Nicholas Chiorazzi

Blood (2024) 144 (Supplement 1): 74.

https://doi.org/10.1182/blood-2024-200296

Published: 2024

Journal Articles

Delivery of Foreign Antigen Selectively to Membrane IgD on CLL and Normal B Cells Leads to Superior T-Cell Activation: A Possible Approach to Restore/Enhance T-Cell Immunity and T-Cell Help

Martina Cardillo, Matthew J Friedman, Anita Ng, Randall S. Davis, Xiao J. Yan, Ashna Shah, Michael Ryan, Peter K Gregersen, Steven L. Allen, Jonathan E Kolitz, Kanti R. Rai, Paolo Ghia, Nicholas Chiorazzi

Blood (2024) 144 (Supplement 1): 1849.

https://doi.org/10.1182/blood-2024-210710

Published: 2024

Journal Articles

Investigation into Intraclonal Heterogeneity of CXCR4 Dim CD5 Bright Chronic Lymphocytic Leukemia Cells Identifies Distinct Activation Signatures

Anita Ng, Andrew Shih, Martina Cardillo, Kristin Lynn Sticco, Houman Khalili, Lita Crichton, William Plunkett, Varsha Gandhi, Nicholas Chiorazzi

Blood (2023) 142 (Supplement 1): 3259.

https://doi.org/10.1182/blood-2023-187957

Published: 2023

Journal Articles

Transcriptomic Analyses Indicate That Pre-Leukemic B Cells from People with Monoclonal B Lymphocytosis Are Surprisingly Much Less Active Than Normal B Cells from People with Monoclonal B Lymphocytosis and from Healthy Donors

Xiao J. Yan, Gonzalo Blanco, Anita Ng, Andrew Shih, Martina Cardillo, Jonathan E Kolitz, Jacqueline C. Barrientos, Steven L. Allen, Joanna M. Rhodes, Kanti R. Rai, Nicholas Chiorazzi

Blood (2023) 142 (Supplement 1): 6512.

https://doi.org/10.1182/blood-2023-191042

Published: 2023

Journal Articles

CLECL1 + CLL Cells: A Key Subset That Drives CLL Survival and Proliferation and Shapes a Th2-Biased Tumor Microenvironment

Shih-Shih Chen, Xiao-Jie Yan, Martina Cardillo, Anita Ng, Andrew Shih, Gonzalo Blanco, Morgan King-Richards, Yu-Ju Chen, Yasmine Kieso, Joanna M. Rhodes, Kanti R Rai, Nicholas Chiorazzi

Blood (2022) 140 (Supplement 1): 1528–1529.

https://doi.org/10.1182/blood-2022-163353

Published: 2022

Journal Articles

Analyses of the Kinetics and Phenotype of Multiple Intraclonal CXCR4/CD5 B Cell Subsets Suggest Differences in Life Cycle Transitioning in CLL

Andrea Nicola Mazzarello, Mark Fitch, Anita Ng, Sabreen Bhuiya, Esha Sharma, Andrew Shih, Martina Cardillo, Steven L Allen, Jonathan E Kolitz, Jacqueline Barrientos, Kanti R Rai, Marc Hellerstein, Nicholas Chiorazzi

Blood (2021) 138 (Supplement 1): 2622.

https://doi.org/10.1182/blood-2021-154224

Published: 2021

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Foreign antigen delivered to CLL B cells via membrane IgD leads to a distinct antigen processing pathway that allows antigen-specific T cell activation that is superior to membrane IgM delivery

Dynamic crosstalk between CLL cells and lymph node fibroblasts promotes a pro-tumor microenvironment

Eradication of the CLECL1+ CLL Subset That Is Prone to Carrying Novel Genomic Mutations and Promoting a Pro-Tumor Microenvironment By a Series of New Monoclonal Antibodies Reactive with Distinct Target Epitopes

Delivery of Foreign Antigen Selectively to Membrane IgD on CLL and Normal B Cells Leads to Superior T-Cell Activation: A Possible Approach to Restore/Enhance T-Cell Immunity and T-Cell Help

Investigation into Intraclonal Heterogeneity of CXCR4 Dim CD5 Bright Chronic Lymphocytic Leukemia Cells Identifies Distinct Activation Signatures

Transcriptomic Analyses Indicate That Pre-Leukemic B Cells from People with Monoclonal B Lymphocytosis Are Surprisingly Much Less Active Than Normal B Cells from People with Monoclonal B Lymphocytosis and from Healthy Donors

CLECL1 + CLL Cells: A Key Subset That Drives CLL Survival and Proliferation and Shapes a Th2-Biased Tumor Microenvironment

Analyses of the Kinetics and Phenotype of Multiple Intraclonal CXCR4/CD5 B Cell Subsets Suggest Differences in Life Cycle Transitioning in CLL

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