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Manuela Zanni
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Journal Articles

Integrated multi-omic profiling identifies molecular subtypes and predicts outcomes in newly diagnosed peripheral T-cell lymphomas

Free
Sadhana Jonnalagadda, Giada Zanirato, Marco Sivestri, Claudia Castellino, Alessandro Re, Chiara Ghiggi, Filippo Ballerini, Rosanna Ciancia, Lorella Orsucci, Antonio Pinto, Sara Usai, Vittorio Stefoni, Francesca Gaia Rossi, Annalisa Arcari, Fiorella Ilariucci, Vittorio Ruggero Zilioli, Leonardo Flenghi, Melania Celli, Stefano Volpetti, Fabio Benedetti, Caterina Patti, Caterina Plenteda, Manuela Zanni, Gerardo Musuraca, Riccardo Bruna, Luca Arcaini, Federica Cavallo, Annalisa Chiappella, Anna Dodero, Paolo Corradini, Cristiana Carniti
Journal: Blood
Blood (2025) 146 (Supplement 1): 1758.
https://doi.org/10.1182/blood-2025-1758
Published: 2025
Journal Articles

Ibrutinib plus R-CHOP followed by maintenance in untreated ABC-DLBCL patients with IPI ≥2: A first analysis of phase II Study  FIL_RI-CHOP

Free
Alice Di Rocco, Annalisa Chiappella, Andrea Evangelista, Valentina Tabanelli, Emanuele Ravano, Chiara Pagani, Federica Cavallo, Elisa Lucchini, Mattia Novo, Attilio Guarini, Anna Merli, Annalisa Arcari, Michele Cimminiello, Francesco Merli, Elsa Pennese, Manuela Zanni, Donato Mannina, Ausilia Gorgone, Guido Gini, Anna Mele, Jacopo Olivieri, Michele Spina, Monica Tani, Andrés José María Ferreri, Chiara Ghiggi, Stefan Hohaus, Marta Coscia, Sara Galimberti, Arcangelo Liso, Mariella Lo Schirico, Benedetta Puccini, Sara Usai, Claudia Peracchio, Alessandra Dondi, Umberto Vitolo, Maurizio Martelli
Journal: Blood
Blood (2025) 146 (Supplement 1): 55.
https://doi.org/10.1182/blood-2025-55
Published: 2025
Journal Articles

Low vitamin d is an unmodifiable adverse prognostic factor in older DLBCL patients: Results from the previd randomized trial by fondazione italiana linfomi (FIL).

Free
Annalisa Arcari, Tanja Lazic, Alessandra Tucci, Benedetta Puccini, Federica Cavallo, Michele Spina, Monica Tani, Sonya De Lorenzo, Ivana Casaroli, Mariantonietta Tafuri, Luigi Petrucci, Michele Cimminiello, Carmine Selleri, Elisa Lucchini, Guido Gini, Barbara Botto, Luca Arcaini, Manuela Zanni, Riccardo Bruna, Jacopo Olivieri, Elsa Pennese, Annarita Conconi, Emanuele Cencini, Salvatrice Mancuso, Chiara Pagani, Manuel Ciceri, Michele Clerico, Caterina Mammi, Luigi Marcheselli, Valentina Tabanelli, Stefano Luminari, Francesco Merli
Journal: Blood
Blood (2025) 146 (Supplement 1): 5462.
https://doi.org/10.1182/blood-2025-5462
Published: 2025
Journal Articles

Increased incidence of secondary malignancies after autologous stem cell transplantation in follicular lymphoma patients: Long-term results of the FIL-FLAZ12 Phase III randomized trial

Free
Rita Tavarozzi, Andrea Evangelista, Manuela Zanni, Simone Ferrero, Alessandra Tucci, Barbara Botto, Silvia Bolis, Pietro Lauzzana, Vittorio Ruggero Zilioli, Benedetta Puccini, Annalisa Arcari, Vincenzo Pavone, Gianluca Gaidano, Monica Tani, Federica Cavallo, Antonio Pinto, Chiara Ghiggi, Domenico Pastore, Lucia Farina, Andrés José María Ferreri, Angelo Palmas, Caterina Patti, Francesca Re, Fabio Benedetti, Salvatore Leotta, Stefano Luminari, Elsa Pennese, Elisa Bossi, Carola Boccomini, Antonella Anastasia, Chiara Bottelli, Donato Mannina, Samantha Pozzi, Catello Califano, Luca Arcaini, Flavio Falcinelli, Giuseppe Pietrantuono, Ilaria Del Giudice, Sara Usai, Jacopo Olivieri, Filippo Gherlinzoni, Attilio Olivieri, Giorgina Specchia, Fabrizio Pomponi, Giovannino Ciccone, Umberto Vitolo, Marco Ladetto
Journal: Blood
Blood (2025) 146 (Supplement 1): 5364.
https://doi.org/10.1182/blood-2025-5364
Published: 2025
Journal Articles

Longitudinal Monitoring of Circulating Tumor DNA to Predict Survival in Newly Diagnosed Peripheral T-Cell Lymphoma Patients

Free
Cristiana Carniti, Sadhana Jonnalagadda, Giada Zanirato, Martina Magni, Eugenio Fardella, Claudia Castellino, Alessandro Re, Chiara Ghiggi, Filippo Ballerini, Rosanna Ciancia, Lorella Orsucci, Antonio Pinto, Sara Usai, Francesca Gaia Rossi, Annalisa Arcari, Fiorella Ilariucci, Vittorio Ruggero Zilioli, Leonardo Flenghi, Melania Celli, Fabio Benedetti, Caterina Patti, Caterina Plenteda, Manuela Zanni, Gerardo Musuraca, Riccardo Bruna, Luca Arcaini, Federica Cavallo, Annalisa Chiappella, Anna Dodero, Paolo Corradini
Journal: Blood
Blood (2024) 144 (Supplement 1): 1580.
https://doi.org/10.1182/blood-2024-201391
Published: 2024
Journal Articles

Impact of Minimal Residual Disease Analysis in the Era of Rituximab Maintenance in Follicular Lymphoma: Data from “FOLL12” Phase III Trial of the Fondazione Italiana Linfomi

Free
Simone Ferrero, Ilaria Del Giudice, Sara Galimberti, Valter Gattei, Luigi Marcheselli, Elisa Genuardi, Daniela Drandi, Mariapia Pironti, Irene Dogliotti, Aurora Maria Civita, Irene Della Starza, Giovanni Manfredi Assanto, Francesca Guerrini, Clara Bono, Riccardo Bomben, Carola Boccomini, Lucia Farina, Jacopo Olivieri, Luca Arcaini, Federica Cavallo, Filippo Ballerini, Gloria Margiotta Casaluci, Vittorio Ruggero Zilioli, Manuela Zanni, Gerardo Musuraca, Anna Merli, Benedetta Bianchi, Silvia Bolis, Vincenzo Pavone, Annalisa Chiarenza, Annalisa Arcari, Catello Califano, Samantha Pozzi, Massimo Massaia, Annarita Conconi, Tommasina Perrone, Donato Mannina, Alessandro Re, Maria Elena Nizzoli, Dimitri Dardanis, Stefano Luminari, Marco Ladetto
Journal: Blood
Blood (2024) 144 (Supplement 1): 339.
https://doi.org/10.1182/blood-2024-194832
Published: 2024
Journal Articles

Rituximab and Lenalidomide (R 2 ) Vs Rituximab Alone As Maintenance Treatment after Chemoimmunotherapy for Elderly Patients with Relapsed/Refractory Follicular Lymphoma (FL): Final Analysis of Renoir Phase III Study of the Fondazione Italiana Linfomi (FIL)

Free
Carola Boccomini, Barbara Botto, Andrea Evangelista, Vittorio Ruggero Zilioli, Antonella Anastasia, Federica Cavallo, Francesco Merli, Manuela Zanni, Monica Tani, Annalisa Chiarenza, Anna Marina Liberati, Annarita Conconi, Paolo Corradini, Alessia Bari, Giorgia Annechini, Gianluca Gaidano, Michele Spina, Roberto Sartori, Claudia Castellino, Benedetta Puccini, Annalisa Arcari, Sara Bigliardi, Giorgia Matta, Michele Merli, Donato Mannina, Dario Marino, Piero Galieni, Fabrizio Ciambelli, Gerardo Musuraca, Chiara Bottelli, Cristina Muzi, Simone Ferrero, Stefano Luminari, Marco Ladetto, Giovannino Ciccone, Umberto Vitolo
Journal: Blood
Blood (2023) 142 (Supplement 1): 982.
https://doi.org/10.1182/blood-2023-174901
Published: 2023
Journal Articles

Positron Emission Tomography Evaluation in Relapsed/Refractory B-Cell Lymphoma Patients Treated with Anti-19 Chimeric Antigen Receptor (CAR) T-Cells in the CART-SIE Observational Study

Free
Anna Dodero, Anna Guidetti, Annalisa Chiappella, Silva Ljevar, Pier Luigi Zinzani, Beatrice Casadei, Stefania Bramanti, Armando Santoro, Patrizia Chiusolo, Alice Di Rocco, Martina Di Palma, Maria Chiara Tisi, Ilaria Cutini, Matteo Giovanni Carrabba, Maurizio Musso, Massimo Martino, Anna Maria Barbui, Mattia Novo, Giovanni Grillo, Marta Lisa Battista, Manuela Zanni, Luca Arcaini, Rosalba Miceli, Cristiana Carniti, Paolo Corradini
Journal: Blood
Blood (2023) 142 (Supplement 1): 3517.
https://doi.org/10.1182/blood-2023-184614
Published: 2023
Journal Articles

Early-Stage Follicular Lymphoma: Learnings from the Final Analysis of the Multicenter Phase II FIL (Fondazione Italiana Linfomi) “Miro” Trial, Combining Local Radiotherapy and MRD-Driven Immunotherapy

Free
Alessandro Pulsoni, Maria Elena Tosti, Simone Ferrero, Stefano Luminari, Alessandra Dondi, Anna Marina Liberati, Natalia Cenfra, Daniela Renzi, Manuela Zanni, Carola Boccomini, Andrés José María Ferreri, Sara Rattotti, Vittorio Ruggero Zilioli, Patrizia Bernuzzi, Silvia Bolis, Gerardo Musuraca, Luca Nassi, Tommasina Perrone, Caterina Stelitano, Antonella Anastasia, Paolo Corradini, Giovanni Partesotti, Francesca Re, Emanuele Cencini, Clara Mannarella, Donato Mannina, Anna Lia Molinari, Monica Tani, Giorgia Annechini, Giovanni Manfredi Assanto, Lavinia Grapulin, Anna Guarini, Marzia Cavalli, Lucia Anna De Novi, Riccardo Bomben, Elena Ciabatti, Barbara Mantoan, Daniela Drandi, Irene Della Starza, Luca Arcaini, Umberto Ricardi, Valter Gattei, Sara Galimberti, Marco Ladetto, Robin Foà, Ilaria Del Giudice
Journal: Blood
Blood (2023) 142 (Supplement 1): 4399.
https://doi.org/10.1182/blood-2023-182946
Published: 2023
Journal Articles

Description of a Clinical Score to Identify PMBL Patients at High Risk of Early-Failure after Rituximab Doxorubicin Back-Bone Chemoimmunotherapy. a FIL Real-World Study

Free
Emilio Iannitto, Monica Balzarotti, Maurizio Martelli, Pier Luigi Zinzani, Alessandra Tucci, Alice Di Rocco, Federica Cavallo, Sara Usai, Anna Guidetti, Emanuele Ravano, Franceso Merli, Barbara Botto, Matteo Pelosini, Cristina Tecchio, Michele Spina, Enrico Derenzini, Silvia Finotto, Brunella Mola, Antonio Pinto, Manuela Zanni, Roberta Battistini, Stefan Hohaus, Irene Dogliotti, Guido Gini, Vittorio Ruggero Zilioli, Sonya De Lorenzo, Anna Dodero, Alessandro Broccoli, Alessandro Maggi, Clara Mannarella, Annalisa Chiarenza, Domenico Pastore, Pellegrino Musto, Caterina Stelitano, Francesco Di Raimondo, Nicola Cascavilla, Nicola Di Renzo, Marilena Salerno, Renato Scalone, Luca Nassi, Attilio Guarini, Caterina Patti, Vita Polizzi, Gabriella Amato, Giovannino Ciccone, Andrea Evangelista, Agostino La Porta, Angelo Genua, Donato Mannina, Ciro Maria Improta, Alessandro Re, Fabrizio Lo Presti, Rosalba Donatella Calogero, Maurizio Musso, Ugo Consoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 986.
https://doi.org/10.1182/blood-2023-178197
Published: 2023
Journal Articles

The Addition of Romidepsin to CHOEP and High-Dose Chemotherapy Plus Stem Cell Transplantation Did Not Ameliorate the Outcome of Untreated Angioimmunoblastic T-Cell or Follicular T-Helper Lymphoma: Subgroup Analysis of Phase II FIL-PTCL13 Study

Free
Annalisa Chiappella, Anna Dodero, Andrea Evangelista, Alessandro Re, Lorella Orsucci, Sara Veronica Usai, Claudia Castellino, Vittorio Stefoni, Antonio Pinto, Manuela Zanni, Rosanna Ciancia, Chiara Ghiggi, Francesca Gaia Rossi, Annalisa Arcari, Fiorella Ilariucci, Vittorio Ruggero Zilioli, Leonardo Flenghi, Melania Celli, Stefano Volpetti, Fabio Benedetti, Filippo Ballerini, Gerardo Musuraca, Riccardo Bruna, Caterina Patti, Francesco Leonardi, Luca Arcaini, Massimo Magagnoli, Federica Cavallo, Valentina Tabanelli, Giovannino Ciccone, Stefano A Pileri, Paolo Corradini
Journal: Blood
Blood (2022) 140 (Supplement 1): 6538–6539.
https://doi.org/10.1182/blood-2022-163824
Published: 2022
Journal Articles

Total Metabolic Tumor Volume Is Confirmed As Independent Prognostic Factor in Treatment Naïve Follicular Lymphoma Patients and Can be Combined with FLIPI2 to Improve Prognostic Accuracy. a FOLL12 Substudy By the Fondazione Italiana Linfomi

Free
Stefano Luminari, Luca Guerra, Carla Minoia, Stephane Chauvie, Antonella Anastasia, Federica Cavallo, Paolo Corradini, Sara Rattotti, Rexhep Durmo, Chiara Ghiggi, Jacopo Olivieri, Simone Ferrero, Gloria Margiotta Casaluci, Luca Nassi, Caterina Stelitano, Francesca Ricci, Vittorio Ruggero Zilioli, Antonio Pinto, Manuela Zanni, Bolis Silvia, Caterina Patti, Michele Merli, Annalisa Chiarenza, Gerardo Musuraca, Patrizia Tosi, Massimo Federico, Annibale Versari
Journal: Blood
Blood (2022) 140 (Supplement 1): 1313–1315.
https://doi.org/10.1182/blood-2022-166225
Published: 2022
Journal Articles

PET-Driven Radiotherapy (RT) in Patients with Low Risk Diffuse Large B-Cell Lymphoma (DLBCL): 5-Year Results of the DLCL10 Multicenter Phase 2 Trial By Fondazione Italiana Linfomi (FIL)

Free
Monica Balzarotti, Umberto Ricardi, Michele Spina, Andrea Evangelista, Alessandra Tucci, Federica Cavallo, Manuela Zanni, Annalisa Arcari, Vittorio Ruggero Zilioli, Roberto Sartori, Francesco Merli, Francesca Re, Umberto Vitolo, Maria Assunta Deidda, Luca Melis, Daniela Dessì, Marcello Rodari, Armando Santoro, Gianluca Gaidano, Giovannino Ciccone, Stephane Chauvie, Maria Giuseppina Cabras
Journal: Blood
Blood (2022) 140 (Supplement 1): 1765–1767.
https://doi.org/10.1182/blood-2022-159759
Published: 2022
Journal Articles

Punctual and kinetic MRD analysis from the Fondazione Italiana Linfomi MCL0208 phase 3 trial in mantle cell lymphoma

Open Access
Clinical Trials & Observations
Simone Ferrero, Daniele Grimaldi, Elisa Genuardi, Daniela Drandi, Gian Maria Zaccaria, Beatrice Alessandria, Marco Ghislieri, Martina Ferrante, Andrea Evangelista, Barbara Mantoan, Gabriele De Luca, Piero Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, Claudia Castellino, Vincenzo Pavone, Mario Petrini, Francesca Re, Stefan Hohaus, Gerardo Musuraca, Nicola Cascavilla, Chiara Ghiggi, Anna Marina Liberati, Sergio Cortelazzo, Marco Ladetto
Journal: Blood
Blood (2022) 140 (12): 1378–1389.
https://doi.org/10.1182/blood.2021014270
Published: 2022
Includes: Supplemental data
Journal Articles

Comparison between R-COMP and R-CHOP in Older Patients with Diffuse Large B-Cell Lymphoma (DLBCL): A Substudy of the Elderly Project By the Fondazione Italiana Linfomi

Free
Francesco Merli, Michele Spina, Alessandra Tucci, Luigi Rigacci, Federica Cavallo, Maria Giuseppina Cabras, Isabel Alvarez, Alberto Fabbri, Alessandro Re, Benedetta Puccini, Simone Ferrero, Sara Veronica Usai, Angela Ferrari, Emanuele Cencini, Elsa Pennese, Vittorio Ruggero Zilioli, Dario Marino, Monica Balzarotti, M. Christina Cox, Manuela Zanni, Alice Di Rocco, Arben Lleshi, Barbara Botto, Stefan Hohaus, Michele Merli, Roberto Sartori, Guido Gini, Luca Nassi, Gerardo Musuraca, Monica Tani, Chiara Bottelli, Sofia Kovalchuk, Francesca Re, Leonardo Flenghi, Anna Lia Molinari, Giuseppe Tarantini, Emanuela Chimienti, Luigi Marcheselli, Caterina Mammi, Stefano Luminari, Annalisa Arcari
Journal: Blood
Blood (2021) 138 (Supplement 1): 2487.
https://doi.org/10.1182/blood-2021-150337
Published: 2021
Journal Articles

A Simplified Geriatric Assessment (sGA) Can Identify Older Patients with Relapse/Refractory (R/R) Aggressive Lymphoma Suitable for Autologous Stem Cell Transplantation (ASCT): Final Results of Recanz Multicentre Prospective Phase 2 Study By the Fondazione Italiana Linfomi (FIL)

Free
Alessandra Tucci, Gerardo Musuraca, Federica Cavallo, Vittorio Ruggero Zilioli, Manuela Zanni, Sabrina Pelliccia, Donato Mannina, Mariagrazia Michieli, Daniele Vallisa, Monica Tani, Francesco Merli, Francesca Re, Luigi Marcheselli, Giulia Campostrini, Chiara Pagani, Daniele Grimaldi, Eliana Valentina Liardo, Alessandro Re, M. Christina Cox, Giuseppe Rossi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2496.
https://doi.org/10.1182/blood-2021-149649
Published: 2021
Journal Articles

Adding Romidepsin to CHOEP in First Line Treatment of Peripheral T-Cell Lymphomas Does Not Improve the Response Rate: Final Analysis of Phase II PTCL13 Study

Free
Annalisa Chiappella, Cristiana Carniti, Alessandro Re, Claudia Castellino, Andrea Evangelista, Valentina Tabanelli, Rosanna Ciancia, Lorella Orsucci, Antonello Pinto, Sara Veronica Usai, Annalisa Arcari, Fiorella Ilariucci, Francesca Gaia Rossi, Fabio Benedetti, Leonardo Flenghi, Chiara Ghiggi, Anna Lia Molinari, Vittorio Stefoni, Stefano Volpetti, Vittorio Ruggero Zilioli, Filippo Ballerini, Riccardo Bruna, Federica Cavallo, Gerardo Musuraca, Caterina Patti, Francesca Re, Monica Tani, Marzia Varettoni, Manuela Zanni, Anna Dodero, Stefano A Pileri, Giovannino Ciccone, Paolo Corradini
Journal: Blood
Blood (2021) 138 (Supplement 1): 134.
https://doi.org/10.1182/blood-2021-153680
Published: 2021
Journal Articles

Rituximab Plus Bendamustine and Cytarabine (R-BAC) in Elderly Patients with Newly Diagnosed Mantle Cell Lymphoma: Long Term Follow-up and Mrd Results of a Phase 2 Study from the Fondazione Italiana Linfomi

Free
Maria Chiara Tisi, Luca Nassi, Caterina Patti, Michele Spina, Simone Ferrero, Monica Tani, Barbara Botto, Anna Lia Molinari, Benedetta Puccini, Emanuele Cencini, Alice Di Rocco, Claudio Chini, Chiara Ghiggi, Renato Zambello, Manuela Zanni, Roberta Sciarra, Martina Ferrante, Caterina Stelitano, Alessandro Re, Stefano Volpetti, Vittorio Ruggero Zilioli, Annalisa Arcari, Francesco Merli, Carlo Visco
Journal: Blood
Blood (2021) 138 (Supplement 1): 384.
https://doi.org/10.1182/blood-2021-153364
Published: 2021
Journal Articles

The Addition of Bortezomib to R-DHAP Does Not Improve the Response Pre-Stem Cell Transplantation Compared to Standard R-DHAP in Young Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Preliminary Results of the Phase II Randomized Trial FIL-VERAL12 of the Fondazione Italiana Linfomi

Free
Annalisa Chiappella, Monica Balzarotti, Chiara Monagheddu, Federica Cavallo, Maria Giuseppina Cabras, Manuela Zanni, Catello Califano, Francesca Re, Angela Giovanna Congiu, Paolo Corradini, Attilio Olivieri, Anna Marina Liberati, Stefano Volpetti, Mariagrazia Michieli, Alessandra Tucci, MD, Monica Tani, Luca Nassi, Rita Mazza, Mattia Novo, Stefano A Pileri, Giovannino Ciccone, Umberto Vitolo
Journal: Blood
Blood (2019) 134 (Supplement_1): 2025.
https://doi.org/10.1182/blood-2019-130786
Published: 2019
Journal Articles

Comprehensive Minimal Residual Disease (MRD) Analysis of the Fondazione Italiana Linfomi (FIL) MCL0208 Clinical Trial for Younger Patients with Mantle Cell Lymphoma: A Kinetic Model Ensures a More Refined Risk Stratification

Free
Simone Ferrero, MD, Barbero Daniela, Mariella Lo Schirico, Andrea Evangelista, PhD, Annalisa Cifaratti, Daniela Drandi, PhD, Elisa Genuardi, PhD, Daniele Grimaldi, Luigia Monitillo, Gian Maria Zaccaria, PhD, Pietro Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, MD, Claudia Castellino, Vincenzo Pavone, Mario Petrini, PhD MD Prof, Francesca Re, MDPhD, Stefan Hohaus, Gerardo Musuraca, MD, Nicola Cascavilla, MD, Angela Giovanna Congiu, Anna Marina Liberati, MD, Giovannino Ciccone, MD, Umberto Vitolo, Sergio Cortelazzo, MD, Marco Ladetto, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 920.
https://doi.org/10.1182/blood-2018-99-114442
Published: 2018