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Journal Articles

Acalabrutinib plus rituximab followed by brexucabtagene autoleucel for frontline treatment of high-risk Mantle Cell Lymphoma: The window-3 clinical trial

Free
Preetesh Jain, Sairah Ahmed, Chi Young Ok, Ranjit Nair, Ahmed Fetooh, Holly Hill, Tatiana Vasilyeva, Ajlan Al Zaki, Anastasiya Evdokimova, Viktor Smirnov, Tolina Turova, Ilya Anosov, Lizzie Sheehan, Selvi Thirumurthi, Anita Deswal, Cezar Iliescu, Vinh Nguyen, Joel Thomas, Naveen Garg, Dhruv Kumar, Cameron Noorbakhsh, Sa Wang, Keyur Patel, Francisco Vega, L. Jeffrey Medeiros, Guilin Tang, Partow Kebriaei, Neeraj Saini, Susan Wu, Bouthaina Dabaja, Nikkita Kotlov, Michael Goldberg, Cara Haymaker, Christopher Flowers, Sattva Neelapu, Michael Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 666.
https://doi.org/10.1182/blood-2025-666
Published: 2025
Journal Articles

Consideration of genomic determinants improves the diagnostic accuracy of oligomonocytic chronic myelomonocytic leukemia

Free
Guillermo Montalban-Bravo, Chong Wu, Juan Jose Rodriguez-Sevilla, Yue Wei, Kelly Chien, Ian Bouligny, Rashmi Kanagal-Shamanna, Anuya Natu, Mark Gurney, Alexandre Bazinet, Danielle Hammond, Alex Bataller, Gautam Borthakur, Nicholas Short, Courtney DiNardo, Tapan Kadia, Farhad Ravandi, Naval Daver, Naveen Pemmaraju, Elias Jabbour, Ghayas Issa, Sa Wang, Keyur Patel, Guilin Tang, L. Jeffrey Medeiros, Terra Lasho, Christy Finke, Aref Al-Kali, Clifford Csizmar, Hassan Alkhateeb, Naseema Gangat, Abhishek Mangaonkar, David Roman-Bravo, Leonor Arenillas, Ayalew Tefferi, Hagop Kantarjian, Guillermo Garcia-Manero, Xavier Calvo, Mrinal Patnaik, Sanam Loghavi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3849.
https://doi.org/10.1182/blood-2025-3849
Published: 2025
Journal Articles

Multimodal assessment of chronic myelomonocytic leukemia with extramedullary involvement reveals RAS pathway activation, adverse outcomes and epithelial-mesenchymal transition

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Sanam Loghavi, Chenxuan Zang, Ziyi Li, Danielle Hammond, Kelly Chien, Alex Bataller, Alexandre Bazinet, Koji Sasaki, Elias Jabbour, Courtney DiNardo, Nicholas Short, Ghayas Issa, Naveen Pemmaraju, Tapan Kadia, Farhad Ravandi, Naval Daver, Gautam Borthakur, Rashmi Kanagal-Shamanna, Peng Wei, Sa Wang, Wei Wang, Hong Fang, Guilin Tang, Sherry Pierce, Carlos Bueso-Ramos, L. Jeffrey Medeiros, Hagop Kantarjian, Guillermo Garcia-Manero, Guillermo Montalban-Bravo
Journal: Blood
Blood (2025) 146 (Supplement 1): 3848.
https://doi.org/10.1182/blood-2025-3848
Published: 2025
Journal Articles

Immune effector cell-associated enterocolitis (IEC-EC) across CAR-T products in myeloma and lymphoma: A real world pharmacovigilance analysis

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Medha Belwadi, Mark Hamilton, Yinghong Wang, Sairah Ahmed, David Richards, Rahul Banerjee, Nilesh Kalariya, Baldeep Pabla, Neeraj Saini, Oren Pasvolsky, J Christine Ye, Mahmoud Gaballa, Sa Wang, L. Jeffrey Medeiros, Francisco Vega, Krina Patel, Swami Iyer
Journal: Blood
Blood (2025) 146 (Supplement 1): 6366.
https://doi.org/10.1182/blood-2025-6366
Published: 2025
Journal Articles

Characteristics and outcomes of CEBPA bZIP in-frame mutations in de novo and treated secondary acute myeloid leukemia

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Sankalp Arora, Wei-Ying Jen, Alexandre Bazinet, Abhishek Maiti, Ghayas Issa, Tapan Kadia, Gautam Borthakur, Farhad Ravandi, Yesid Alvarado Valero, Musa Yilmaz, Chi Young Ok, Hong Fang, Andres Quesada, Rashmi Kanagal-Shamanna, Fatima Jelloul, Keyur Patel, L. Jeffrey Medeiros, Hagop Kantarjian, Naval Daver, Courtney DiNardo, Sanam Loghavi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5167.
https://doi.org/10.1182/blood-2025-5167
Published: 2025
Journal Articles

When lymphoma mimics adenocarcinoma: signet ring morphology in follicular lymphoma

Free
Xenia Parisi, L. Jeffrey Medeiros
Journal: Blood
Blood (2025) 145 (18): 2104.
https://doi.org/10.1182/blood.2025028395
Published: 2025
Journal Articles

Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory

Free
Iman Sarami, Ruchi Singhal, Mark Routbort, Koji Sasaki, Daniel Domogala III, Gokce A. Toruner, Shibu Ninan, Nitin Jain, Keyur P. Patel, Elias Jabbour, Hagop M. Kantarjian, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Raja Luthra, Guilin Tang, Rashmi Kanagal-Shamanna
Journal: Blood
Blood (2024) 144 (Supplement 1): 4224.
https://doi.org/10.1182/blood-2024-211561
Published: 2024
Journal Articles

Large Cell Transformation in Mycosis Fungoides & Sezary Syndrome: An Analysis of 445 Cases

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Rishabh Lohray, Lei Feng, Auris O Huen, Iyanuoluwa Ogundipe, Luis Malpica, Bouthaina S. Dabaja, Julia Dai, Jillian R. Gunther, Chitra Hosing, Roberto N. Miranda, L. Jeffrey Medeiros, Samer A. Srour, Jeremy Ramdial, Francisco Vega, Mansoor Noorani, Amy A. Ayers, Penny Q. Fang, Luis E. Fayad, Chelsea C. Pinnix, Madeleine Duvic, Jie Xu, Christopher R. Flowers, Susan Y. Wu, Kunhwa Kim, Carlos P Torres-Cabala, Swaminathan P Iyer, Ranjit Nair
Journal: Blood
Blood (2024) 144 (Supplement 1): 1679.
https://doi.org/10.1182/blood-2024-209213
Published: 2024
Journal Articles

Age-Related Prognoses of Genetic Subtypes in B-Cell Acute Lymphoblastic Leukemia/Lymphoma (B-ALL): Insights from a Decade of National Data

Free
Ting Zhou, Nicholas J. Short, Nitin Jain, Keyur P. Patel, Elias Jabbour, Hagop M. Kantarjian, L. Jeffrey Medeiros, Bryan Iorgulescu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2024-208340
Published: 2024
Journal Articles

An Integrated Spatial, Codex, and Genomic Analysis Predicts Responsiveness and Survival in the Phase II Combination of Pembrolizumab and Romidepsin in PTCL

Free
Ranjit Nair, Daniela E. Duenas, Jingjing Liu, Rishab Prakash, Chen Zhou, Ayse A Koksoy, Jie Xu, Salome A McAllen, Luis Malpica, Raja Luthra, Francisco Vega, Roberto N. Miranda, Jianhua Zhang, L. Jeffrey Medeiros, Cara L Haymaker, Christopher R. Flowers, Sattva S. Neelapu, Swami P. Iyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 455.
https://doi.org/10.1182/blood-2024-211900
Published: 2024
Journal Articles

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

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Andrew L. Feldman, Guangzhen Hu, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Jimena B. Gimenez, Farah M. Salama, Min Shi, Elías Campo, Wing Chung Chan, James R. Cook, Giorgio Inghirami, Elaine S. Jaffe, Ryan Morin, Phillipp W. Raess, Andreas Rosenwald, Kerry J. Savage, Louis M. Staudt, George W. Wright, Catalina Amador, Jan Delabie, Timothy C. Greiner, Javeed Iqbal, Laura K. Hilton, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Graham W. Slack, Susan L. Slager, Joo Y. Song, Hao-Wei Wang, Ahmed A. Aljudi, Stephen M. Ansell, Carlos Barrionuevo, James R. Cerhan, Jennifer R. Chapman-Fredricks, Weina Chen, Laurence de Leval, Alejandro A. Gru, David L. Jaye, Liuyan Jiang, Brad S. Kahl, Kennosuke Karube, Young Hyeh Ko, Eric Mou, Matthew J. Maurer, L. Jeffrey Medeiros, Roberto N. Miranda, Naoki Oishi, Perry M. Anamarija, Akira Satou, Xueju Wang, Ryan A. Wilcox, Xiaojun Wu, Tadashi Yoshino, Yu Zeng
Journal: Blood
Blood (2024) 144 (Supplement 1): 2974.
https://doi.org/10.1182/blood-2024-202410
Published: 2024
Journal Articles

Acalabrutinib with Rituximab Is Highly Effective First Line Treatment for Older Patients with Mantle Cell Lymphoma

Free
Preetesh Jain, Chi Young Ok, Jason R. Westin, Holly A Hill, Ranjit Nair, Swami P. Iyer, Ahmed Fetooh, Hun Ju Lee, Sairah Ahmed, Rashmi Kanagal-Shamanna, Fatima Z Jelloul, Luis Malpica, Yang Liu, Yijing Li, Lei Feng, Maria Badillo, Selvi Thirumurthi, Anita Deswal, Cezar Iliescu, Vinh Quang Nguyen, Anastasiia A. Bolshakova, Dmitry Tabakov, Michael G Goldberg, Andrey Tyshevich, Tatiana Vasileva, Daria Shavronskaya, Krystle Nomie, Guilin Tang, Keyur P. Patel, Francisco Vega, L. Jeffrey Medeiros, Christopher R. Flowers, Michael Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3038.
https://doi.org/10.1182/blood-2024-206042
Published: 2024
Journal Articles

Application of Next-Generation Cytogenetics in a Clinical Laboratory for Diagnostic Work-up of Myelodysplastic Syndromes/Neoplasms (MDS)

Free
Anindita Ghosh, Guilin Tang, Hui Yang, Koji Sasaki, Gokce A. Toruner, Juan Jose Rodriguez-Sevilla, Raja Luthra, Danielle Hammond, L. Jeffrey Medeiros, Carlos E. Bueso-Ramos, Guillermo Montalban-Bravo, Kelly S. Chien, Guillermo Garcia-Manero, Rashmi Kanagal-Shamanna
Journal: Blood
Blood (2024) 144 (Supplement 1): 7519.
https://doi.org/10.1182/blood-2024-211967
Published: 2024
Journal Articles

Myeloid Progenitor Cells with Preleukemic Immunophenotypes Are Common in Myelodysplasia-Related and NPM1- mutated Acute Myeloid Leukemia and Should Not be Interpreted As Measurable Residual Disease

Free
Sanam Loghavi, Sa A. Wang, Wei-Ying Jen, Wei Wang, Hong Fang, Shaoying Li, Sofia A. Garces, Andres E Quesada, Jie Xu, Chi Young Ok, Shimin Hu, Jeffrey L. Jorgensen, Guilin Tang, Cedric Nasnas, Omer Karrar, Ghayas C. Issa, Naval Daver, Courtney D. DiNardo, Tapan M. Kadia, Hagop M. Kantarjian, L. Jeffrey Medeiros, Farhad Ravandi, Nicholas J. Short
Journal: Blood
Blood (2024) 144 (Supplement 1): 4336.
https://doi.org/10.1182/blood-2024-209462
Published: 2024
Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Prognostically Poor Subgroup Enriched for Myelodysplasia-Related Subtypes and Distinct from Other RAS Pathway Mutant AML

Free
Darren Lee, Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Mark Routbort, Keyur P. Patel, Christopher J. Walker, Jill Buss, Andrew Stiff, Andrea Laganson, Courtney D. DiNardo, Naval Daver, Gautam Borthakur, Tapan M. Kadia, Farhad Ravandi, Andrew J. Carroll, Jonathan E Kolitz, Bayard L Powell, William Blum, Maria R. Baer, Guido Marcucci, Geoffrey L. Uy, Wendy Stock, Richard M. Stone, L. Jeffrey Medeiros, Jeffrey W. Tyner, Robert L. Bowman, John C. Byrd, James S. Blachly, Sanam Loghavi, Ann-Kathrin Eisfeld, Linde A. Miles
Journal: Blood
Blood (2024) 144 (Supplement 1): 2921.
https://doi.org/10.1182/blood-2024-210110
Published: 2024
Journal Articles

Outcomes in Patients with Relapsed Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Treated with CAR-T Cell Therapies or Salvage Chemotherapy - a Single-Institution Experience

Free
Ranjit Nair, Iyanuoluwa Ogundipe, Jillian Gunther, L. Jeffrey Medeiros, Preetesh Jain, Loretta J. Nastoupil, Chelsea Camille Pinnix, Luis Malpica, Sairah Ahmed, Roberto Miranda, Luis Fayad, Raphael E Steiner, Frederick Hagemeister, Hun Ju Lee, Maria Alma Rodriguez, Paolo Strati, Dai Chihara, Michael Wang, Yago Nieto, Jeremy Ramdial, Ajlan Al Zaki, Chijioke Nze, Michael R. Green, Bouthaina S. Dabaja, Jie Xu, Beenu Thakral, Sattva S. Neelapu, Francisco Vega, Christopher R. Flowers, Penny Fang, Jason Westin, Lei Feng, Swami P. Iyer
Journal: Blood
Blood (2023) 142 (Supplement 1): 6327.
https://doi.org/10.1182/blood-2023-191096
Published: 2023
Journal Articles

Optical Genomic Mapping Provides Unique Findings in Various Types of Myeloid Neoplasms

Free
Andres E Quesada, Gokce A. Toruner, Zhenya Tang, Shimin Hu, Jie Xu, Shaoying Li, Farhad Ravandi, Hagop M. Kantarjian, M. James You, L. Jeffrey Medeiros, Guilin Tang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4303.
https://doi.org/10.1182/blood-2023-177803
Published: 2023
Journal Articles

Developing Deep Learning Pipeline of Whole-Slide Images for Enhanced Diffuse Large B Cell Lymphoma (DLBCL) Subtyping and Outcome Prediction: Leveraging Self-Attention Transformer for Training and Inference

Free
Chen Zhou, Jie Xu, Rishab Prakash, Carlos P Torres-Cabala, Cheng-bang Chen, Kamesh Madduri, Arvind Rao, Greeshma Agasthya, Francisco Vega, Dennis O'Malley, L. Jeffrey Medeiros, Soundar Kumara, Swami P. Iyer
Journal: Blood
Blood (2023) 142 (Supplement 1): 904.
https://doi.org/10.1182/blood-2023-187291
Published: 2023
Journal Articles

Acalabrutinib with Rituximab As First-Line Therapy for Older Patients with Mantle Cell Lymphoma - a Phase II Clinical Trial

Free
Preetesh Jain, Chi Young OK, Loretta J. Nastoupil, Jason Westin, Holly A Hill, Ranjit Nair, Swami P. Iyer, Ahmed Fetooh, Hun Ju Lee, Sairah Ahmed, Rashmi Kanagal-Shamanna, Fatima Z Jelloul, Luis Enrique Malpica Castillo, Yang Liu, Yijing Li, Jovanny Vargas, Lei Feng, Maria Badillo, Selvi Thirumurthi, Guofan Xu, Anita Deswal, Cezar Iliescu, Vinh Quang Nguyen, Guilin Tang, Keyur P. Patel, Francisco Vega, L. Jeffrey Medeiros, Michael L. Wang, Christopher R. Flowers
Journal: Blood
Blood (2023) 142 (Supplement 1): 3036.
https://doi.org/10.1182/blood-2023-181216
Published: 2023
Journal Articles

Does Detection of <20% Lymphoblasts in Patients with CML Herald Imminent Blast Crisis? a Study from BCR::ABL1 Pathology Group

Free
Zimu Gong, Lianqun Qiu, Joseph DiGiuseppe, Mengxing Xue, Lorinda Soma, Wei Wang, Yi Zhou, Qi Shen, Mingqing Zhu, Anisha Naik, Weina Chen, Wei J Wang, Sa A. Wang, L. Jeffrey Medeiros, Elias Jabbour, Hagop M. Kantarjian, Jorge Cortes, Jerald P. Radich, Joseph D. Khoury, Andreas Hochhaus, Jane F Apperley, Suning Chen, Kikkeri N Naresh, Shimin Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6364.
https://doi.org/10.1182/blood-2023-187020
Published: 2023