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Journal Articles

A new HDAC1/2 degrader increases HbF production in human CD34⁺ cells at non-cytotoxic, differentiation-preserving dose

Victor Gabriel de Faria Pastre, Aline Renata Pavan, Marina Dorigatti Borges, Carolina Lanaro, Daniela Pinheiro Leonardo, Dulcineia Martins de Albuquerque, Jean Leandro Dos Santos, Fernando Costa

Blood (2025) 146 (Supplement 1): 6491.

https://doi.org/10.1182/blood-2025-6491

Published: 2025

Journal Articles

Evaluation of new deferasirox-derived compounds for the treatment of iron overload

Marina Dorigatti Borges, João Lucas Bruno Prates, Victor Gabriel de Faria Pastre, Aline Renata Pavan, Daniela Pinheiro Leonardo, Dulcineia Martins de Albuquerque, Carolina Lanaro, Fábio Henrique da Silva, Jean Leandro Dos Santos, Fernando Costa

Blood (2025) 146 (Supplement 1): 1132.

https://doi.org/10.1182/blood-2025-1132

Published: 2025

Journal Articles

Novel Selective HDAC1/2 Inhibitor 2-Aminobenzamide Derivative Potently Induces Fetal Hemoglobin

Victor Gabriel de Faria Pastre, Aline Renata Pavan, Carolina Lanaro, Dulcineia Albuquerque, Rafael Consolin Chelucci, Leonardo Luiz Gomes Ferreira, Adriano D. Andricopulo, Jean Leandro Dos Santos, Fernando Ferreira Costa

Blood (2024) 144 (Supplement 1): 3868.

https://doi.org/10.1182/blood-2024-208290

Published: 2024

Journal Articles

Cereblon-Based Compounds for Induction of HbF

Aline Renata Pavan, Victor Gabriel de Faria Pastre, Carolina Lanaro, Dulcineia Albuquerque, Joshua P. Smalley, Urvashi Patel, John W. R. Schwabe, Shaun M. Cowley, James T. Hodgkinson, Jean Leandro Dos Santos, Fernando Ferreira Costa

Blood (2024) 144 (Supplement 1): 1109.

https://doi.org/10.1182/blood-2024-208177

Published: 2024