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Journal Articles

NLRP6 regulates ZAP-70-erk signaling in both murine and human T cells and influences acute graft-versus-host disease(GVHD)

Free
Eri Matsuki, Masahiro Miyata, Jana Gawron, Masahiro Suto, Hiroya Tamaki, Hideaki Fujiwara, Yuki Ishizawa, Erika Sekiguchi, Tayu Tobai, Sae Ushio, Katherine Oravecz-Wilson, Grace Chen, Isao Tawara, Kazunobu Ichikawa, Masafumi Watanabe, Kenichi Ishizawa, Hisayuki Yokoyama, Dan Peltier, Bruce Blazar, Robert Zeiser, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2025) 146 (Supplement 1): 4090.
https://doi.org/10.1182/blood-2025-4090
Published: 2025
Journal Articles

Mortality associated with warm autoimmune hemolytic anemia among Medicare beneficiaries

Free
Louis Jackson, Maryia Zhdanava, Jacqueline Pesa, Porpong Boonmak, Grace Chen, Daisy Liu, Dominic Pilon, Zia Choudhry, Surbhi Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 2694.
https://doi.org/10.1182/blood-2025-2694
Published: 2025
Journal Articles

Association between increased Patients' out-of-pocket costs for apixaban and oral anticoagulant discontinuation in high-risk patients with atrial fibrillation - a retrospective Medicare claims study

Free
Dominick Latremouille-Viau, Aolin Wang, Dong Cheng, Serina Deeba, Anandkumar Dubey, Radhika Gomez, Abigail Zion, Grace Chen, Elisabeth Vodicka, Dionne Hines
Journal: Blood
Blood (2025) 146 (Supplement 1): 954.
https://doi.org/10.1182/blood-2025-954
Published: 2025
Journal Articles

Baseline intratumoral CD4⁺ T-cell abundance and frequency correlates with durable clinical response to acalabrutinib, venetoclax, and obinutuzumab (AVO) treatment in Mantle Cell Lymphoma

Free
Mingzeng Zhang, Billie Porter, Kathleen Pfaff, Anne Carlisle, Grace Chen, Lydie Debaize, Salah Abdulkarim, Haocheng Wang, Juniper Mai, Alexa Batingana, Jenalyn Weekes, Paul Branch, Liliana Guerrero, Mikaela McDonough, Reid Merryman, Christine Ryan, Austin Kim, Scott Rodig, Mark Murakami
Journal: Blood
Blood (2025) 146 (Supplement 1): 3551.
https://doi.org/10.1182/blood-2025-3551
Published: 2025
Journal Articles

In Vivo panCAR-Mediated Depletion of B Cells in Non-Human Primates Using a Circular (oRNA®) Anti-CD20 CAR

Free
Juliet Crabtree, Akinola Emmanuel, Ganapathy Subramanian Sankaran, Jui Dutta-Simmons, Karolina Kosakowska, Tracy Dimezzo, Ian Langer, Prapti Vyas, David Soto, Akshi Thakkar, Grace Chen, Maja Sedic, Scott Barros, Allen Horhota, Isin Dalkilic-Liddle, LT Thiruneelakantapillai, Muthusamy Jayaraman, Megan Hoban, Frank Neumann, Robert Mabry
Journal: Blood
Blood (2024) 144 (Supplement 1): 3427.
https://doi.org/10.1182/blood-2024-210256
Published: 2024
Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Free
Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2021-152089
Published: 2021
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Free
Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

Targeting Neutrophil Aging and the Microbiota for the Treatment of Sickle Cell Disease

Free
Dachuan Zhang, MS, Grace Chen, PhD, Deepa Manwani, MD, Arthur Mortha, PhD, Chunliang Xu, PhD, Jeremiah J. Faith, PhD, Robert D. Burk, MD, Yuya Kunisaki, MD PhD, Jung-Eun Jang, PhD, Christoph Scheiermann, PhD, Miriam Merad, MD PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2015) 126 (23): 279.
https://doi.org/10.1182/blood.V126.23.279.279
Published: 2015
Journal Articles

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

Free
Tomomi Toubai, MD PhD, Corinne Rossi, MD, Hiroya Tamaki, MD PhD, Nathan Mathewson, PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Yaping Sun, MD PhD, Grace Chen, MD PhD, Pavan Reddy, MD
Journal: Blood
Blood (2015) 126 (23): 148.
https://doi.org/10.1182/blood.V126.23.148.148
Published: 2015
Journal Articles

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Free
Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, PhD, Chen Liu, MD, PhD, Nathan Mathewson, BSPS, Yaping Sun, MD PhD MS, Grace Chen, MD, Pavan Reddy, MD
Journal: Blood
Blood (2014) 124 (21): 2421.
https://doi.org/10.1182/blood.V124.21.2421.2421
Published: 2014
Journal Articles

Vaso-Occlusion-Promoting Neutrophil Mac-1 Integrin Activation in Human Sickle Cell Crises Is Stabilized By a Single Dose of Intravenous Gammaglobulin

Free
Deepa Manwani, MD, Grace Chen, PhD, Veronica Carullo, MD, Hillel W Cohen, DrPH, MPH, Stelian Serban, Olugbenga Olowukere, Jungeun Jang, Matthew Huggins, Henny H Billett, MD, George F. Atweh, MD, Paul S. Frenette, MD, Patricia A Shi, MD
Journal: Blood
Blood (2014) 124 (21): 4089.
https://doi.org/10.1182/blood.V124.21.4089.4089
Published: 2014
Journal Articles

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

Free
Grace Chen, Dachuan Zhang, Tobias A. Fuchs, Deepa Manwani, Denisa D. Wagner, Paul S. Frenette
Journal: Blood
Blood (2014) 123 (24): 3818–3827.
https://doi.org/10.1182/blood-2013-10-529982
Published: 2014
Includes: Supplemental data
Journal Articles

Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis

Free
Grace Chen, PhD, Tobias A. Fuchs, PhD, Denisa D. Wagner, PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2013) 122 (21): 184.
https://doi.org/10.1182/blood.V122.21.184.184
Published: 2013