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Journal Articles

Impact of CAR-T cells expansion and tumor burden on the outcome after inotuzumab ozogamicin as bridging therapy in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia.

Patricia Alcalde-Mellado, Victoria Ruiz-Maldonado, Javier Delgado Serrano, Laura Perez-Ortega, Marta Reinoso -Segura, Luzalba Sanoja Flores, Belén Sierro, Estefania Garcia-Guerrero, Concepción Pérez de Soto, José María Pérez Hurtado, José González-Campos, José Antonio Pérez-Simón, Agueda Molinos-Quintana, Teresa Caballero

Blood (2025) 146 (Supplement 1): 2324.

https://doi.org/10.1182/blood-2025-2324

Published: 2025

Journal Articles

Innovative Bone Marrow CAR-T Cell Manufacturing for AML: Enhancing Viability and Tumor Migration

Jose Antonio Bejarano Garcia, Daniel Primo, Maria Jose Palacios Barea, Belén Sierro, Beatriz Guijarro-Albaladejo, Xian Weng, Miranda Omenaca, Estefania Garcia-Guerrero, Joan Ballesteros, Jose Antonio Pérez-Simón

Blood (2024) 144 (Supplement 1): 3478.

https://doi.org/10.1182/blood-2024-201457

Published: 2024

Journal Articles

Assessing CAR-T Cell Product Quality: The Crucial Role of Metabolic and Persistence Analysis after Antigen Stimulation

Beatriz Guijarro-Albaladejo, Belén Sierro, Virginia Escamilla Gómez, Paola Hernández-Díaz, María de la Rosa-Garrido, Inmaculada Carrasco Brocal, Jose Antonio Bejarano Garcia, Patricia Alcalde Mellado, Alfonso Rodriguez Gil, Maribel Lara-Chica, José Antonio Pérez-Simón, Estefania Garcia-Guerrero

Blood (2024) 144 (Supplement 1): 2096.

https://doi.org/10.1182/blood-2024-204757

Published: 2024

Journal Articles

Validation of GMP Lentiviral Vector Production for CAR T-Cell Therapy in the Spanish Public Health System: Development of New QC Required By Aemps (Spanish FDA)

Maribel Lara Chica, María De La Rosa-Garrido, Blanca Arribas-Arribas, Miguel-Ángel Montiel-Aguilera, Raquel Muñoz-García, María Bermejo-González, Esteban Márquez-Pérez, Belén Sierro, Paola Hernández-Díaz, Beatriz Guijarro-Albaladejo, Inmaculada Carrasco Brocal, Virginia Escamilla Gómez, José Antonio Pérez-Simón, Gloria Carmona, Estefania Garcia-Guerrero

Blood (2024) 144 (Supplement 1): 7257.

https://doi.org/10.1182/blood-2024-207219

Published: 2024

Journal Articles

Role of Antiapoptotic Protein Mcl1 in Graft-Versus-Host Disease

Jose Antonio Bejarano Garcia, Melanie Nufer, Maria Jose Palacios Barea, Beatriz Guijarro-Albaladejo, Inmaculada Carrasco Brocal, Belén Sierro, Estefania Garcia-Guerrero, Maribel Lara Chica, Teresa Caballero, Alfonso Rodríguez-Gil, Jose Antonio Pérez-Simón

Blood (2024) 144 (Supplement 1): 3395.

https://doi.org/10.1182/blood-2024-200823

Published: 2024

Journal Articles

New Optimized Academic Anti-BCMA CAR (CARTemis-1): How Does the Manufacturing Process Impact CAR-T Cell Features?

Belén Sierro-Martínez, Virginia Escamilla Gomez, Laura Perez-Ortega, Beatriz Guijarro-Albaladejo, Paola Hernández-Díaz, María de la Rosa-Garrido, Maribel Lara-Chica, Juan Luis Reguera, Luzalba Sanoja Flores, Blanca Arribas-Arribas, Miguel-Ángel Montiel-Aguilera, Gloria Carmona, Maria-Jose Robles, Teresa Caballero, Javier Briones, Hermann Einsele, Michael Hudecek, Jose A. Pérez-Simón, Estefania Garcia-Guerrero

Blood (2023) 142 (Supplement 1): 6866.

https://doi.org/10.1182/blood-2023-186095

Published: 2023

Journal Articles

Detection, Monitoring and Cell Kinetics of Circulating CAR-T Cells in B-Cell Malignancies

Belén Sierro, Clara Beatriz Garcia-Calderon, Luzalba Sanoja-Flores, Victoria Ruiz-Maldonado, Javier Delgado Serrano, Agueda Molinos-Quintana, Juan Luis Reguera, Beatriz Guijarro-Albaladejo, Marta Reinoso-Segura, Estefania Garcia-Guerrero, Jose A. Perez-Simon, Teresa Caballero

Blood (2022) 140 (Supplement 1): 7550–7551.

https://doi.org/10.1182/blood-2022-163106

Published: 2022

Journal Articles

ATRA Augments BCMA Expression on Myeloma Cells and Enhances Recognition By BCMA-CAR T-Cells

Estefania Garcia-Guerrero, PhD, Luis Gerardo Rodríguez-Lobato, Sophia Danhof, MD, Belén Sierro-Martínez, Ralph Goetz, Markus Sauer, Jose A. Perez-Simon, MD PhD, Hermann Einsele, MD, Michael Hudecek, MD, Sabrina Prommersbe

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-142572

Published: 2020

Journal Articles

Pre-Clinical Trial to Evaluate the Efficacy of Delayed Administration of Ixazomib in the Prophylaxis of Chronic Graft-Versus-Host Disease

Teresa Ramos, PhD, Alfonso Rodríguez-Gil, PhD, Melanie Nufer, María Victoria Barbado, PhD, Estefania Garcia Guerrero, PhD, Rocio Caracuel-García, Tehcnician, Teresa Caballero-Velázquez, MD PhD, José A. Pérez-Simón, MD PhD

Blood (2018) 132 (Supplement 1): 4521.

https://doi.org/10.1182/blood-2018-99-118098

Published: 2018

Journal Articles

Identification and Isolation of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients through the Identification of T-Cells Capable to Establish Stable Interactions with Leukemic Cells

Estefania Garcia-Guerrero, Luis I. Sanchez-Abarca, PhD, Esther Domingo, PhD, Teresa Ramos, PhD, Jose Antonio Bejarano-García, Jose A Gonzalez-Campos, MD, Teresa Caballero-Velázquez, MD PhD, José A. Pérez-Simón, MD PhD

Blood (2018) 132 (Supplement 1): 3336.

https://doi.org/10.1182/blood-2018-99-118118

Published: 2018

Journal Articles

CCR6, IL7R, FAS and Madcam-1 Single Nucleotide Polymorphisms Are Associated with Higher Incidence of Infections in Allogeneic Stem-Cell Transplant from a Related Donor after a Reduced Intensity Conditioning Regimen: A Multicenter Experience

Blood (2017) 130 (Supplement 1): 3208.

https://doi.org/10.1182/blood.V130.Suppl_1.3208.3208

Published: 2017

Journal Articles

Upregulation of CD38 Expression on Multiple Myeloma Cells By the HDAC Inhibitor Ricolinostat Augments the Efficacy of Daratumumab

Estefania Garcia-Guerrero, Sophia Danhof, Martin Schreder, MD, José A. Pérez-Simón, Hermann Einsele, Michael Hudecek

Blood (2017) 130 (Supplement 1): 1803.

https://doi.org/10.1182/blood.V130.Suppl_1.1803.1803

Published: 2017

Journal Articles

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab

Estefanía García-Guerrero, Tea Gogishvili, Sophia Danhof, Martin Schreder, Celine Pallaud, Jose Antonio Pérez-Simón, Hermann Einsele, Michael Hudecek

Blood (2017) 129 (25): 3386–3388.

https://doi.org/10.1182/blood-2017-03-770776

Published: 2017

Includes: Supplemental data

Journal Articles

Panobinostat Induces Upregulation of CD38 and Augments the Anti-Myeloma Efficacy of Daratumumab in Pre-Clinical Models

Estefania Garcia-Guerrero, Tea Gogishvili, PhD, Sophia Danhof, MD, Martin Schreder, MD, Celine Pallaud, PhD, Thomas Lehmann, PhD, Hermann Einsele, MD, Michael Hudecek, MD

Blood (2016) 128 (22): 4481.

https://doi.org/10.1182/blood.V128.22.4481.4481

Published: 2016

Journal Articles

Molecular Dynamics As a Computational Tool to Study the Immune Reactivity: Identification of Conformational Changes in the Major Histocompatibility Complex

Estefania Garcia Guerrero, Jose Antonio Pérez Simon, Luis Ignacio Sánchez Abarca, Irene Diaz Moreno, Miguel Angel De la rosa, Antonio Diaz Quintana

Blood (2014) 124 (21): 2735.

https://doi.org/10.1182/blood.V124.21.2735.2735

Published: 2014

Journal Articles

Myelomatous Plasma Cells Display An Intermediate Gene Expression Pattern Between a Normal Plasma Cell and a Memory B Cell

Alicia Baez, Jose Ignacio Piruat, Ph.D, Teresa Caballero-Velazquez, María Victoria Barbado, Ph.D, Isabel Alvarez-Laderas, Africa Millan-Ucles, Mayte Medrano, Estefania Garcia-Guerrero, Luis Ignacio Sanchez-Abarca, Ph.D., Ildefonso Espigado, Jose Antonio Perez-Simón, MD, PhD

Blood (2013) 122 (21): 1892.

https://doi.org/10.1182/blood.V122.21.1892.1892

Published: 2013

Journal Articles

Memory B Cells Display Changes In The Expression Pattern Of Genes Related To Cell Survival In Elderly Individuals

Alicia Baez, Isabel Alvarez-Laderas, Jose Ignacio Piruat, Ph.D, Teresa Caballero-Velazquez, Africa Millan-Ucles, María Victoria Barbado, Ph.D, Mayte Medrano, Estefania Garcia-Guerrero, Luis Ignacio Sanchez-Abarca, Ph.D., Jose Antonio Perez-Simón, MD, PhD, Ildefonso Espigado

Blood (2013) 122 (21): 4893.

https://doi.org/10.1182/blood.V122.21.4893.4893

Published: 2013

Journal Articles

Molecular Dynamics As a Computational Tool To Analyze Lymphocyte Alloreactivity In Hematopoietic Transplant Recipients

Estefania Garcia Guerrero, Irene Diaz Moreno, Miguel Angel De la rosa, Jose Antonio Pérez Simón, MD, PhD, Antonio Diaz Quintana

Blood (2013) 122 (21): 1049.

https://doi.org/10.1182/blood.V122.21.1049.1049

Published: 2013

Journal Articles

Intensification of Chemotherapeutic Regimens and Hematopoietic Stem Cell Transplantation Are Responsible for Improved Overall Survival in Adult Acute Lymphoblastic Leukemia in a Single Center Over the Last Forty Years

Estrella Carrillo, MD, Nancy Rodriguez, Juan Francisco Dominguez, Jose Gonzalez, MD, Jose Francisco Falantes, MD, Isabel Montero, MD, M. Luz Martino, MD, Francisco Márquez-Malaver, Ricardo Parody, MD, Estefania Garcia-Guerrero, Jose Antonio Perez-Simón, Sr., MD, PhD, Ildefonso Espigado, MD, PhD

Blood (2011) 118 (21): 4227.

https://doi.org/10.1182/blood.V118.21.4227.4227

Published: 2011

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Impact of CAR-T cells expansion and tumor burden on the outcome after inotuzumab ozogamicin as bridging therapy in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia.

Innovative Bone Marrow CAR-T Cell Manufacturing for AML: Enhancing Viability and Tumor Migration

Assessing CAR-T Cell Product Quality: The Crucial Role of Metabolic and Persistence Analysis after Antigen Stimulation

Validation of GMP Lentiviral Vector Production for CAR T-Cell Therapy in the Spanish Public Health System: Development of New QC Required By Aemps (Spanish FDA)

Role of Antiapoptotic Protein Mcl1 in Graft-Versus-Host Disease

New Optimized Academic Anti-BCMA CAR (CARTemis-1): How Does the Manufacturing Process Impact CAR-T Cell Features?

Detection, Monitoring and Cell Kinetics of Circulating CAR-T Cells in B-Cell Malignancies

ATRA Augments BCMA Expression on Myeloma Cells and Enhances Recognition By BCMA-CAR T-Cells

Pre-Clinical Trial to Evaluate the Efficacy of Delayed Administration of Ixazomib in the Prophylaxis of Chronic Graft-Versus-Host Disease

Identification and Isolation of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients through the Identification of T-Cells Capable to Establish Stable Interactions with Leukemic Cells

CCR6, IL7R, FAS and Madcam-1 Single Nucleotide Polymorphisms Are Associated with Higher Incidence of Infections in Allogeneic Stem-Cell Transplant from a Related Donor after a Reduced Intensity Conditioning Regimen: A Multicenter Experience

Upregulation of CD38 Expression on Multiple Myeloma Cells By the HDAC Inhibitor Ricolinostat Augments the Efficacy of Daratumumab

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab

Panobinostat Induces Upregulation of CD38 and Augments the Anti-Myeloma Efficacy of Daratumumab in Pre-Clinical Models

Molecular Dynamics As a Computational Tool to Study the Immune Reactivity: Identification of Conformational Changes in the Major Histocompatibility Complex

Myelomatous Plasma Cells Display An Intermediate Gene Expression Pattern Between a Normal Plasma Cell and a Memory B Cell

Memory B Cells Display Changes In The Expression Pattern Of Genes Related To Cell Survival In Elderly Individuals

Molecular Dynamics As a Computational Tool To Analyze Lymphocyte Alloreactivity In Hematopoietic Transplant Recipients

Intensification of Chemotherapeutic Regimens and Hematopoietic Stem Cell Transplantation Are Responsible for Improved Overall Survival in Adult Acute Lymphoblastic Leukemia in a Single Center Over the Last Forty Years

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