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Earl Fields
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Journal Articles

Efficacy and safety of osivelotor in participants with sickle cell disease in a 12-week phase 2, multicenter, open-label, dose-finding trial and extension study

Free
Santosh Saraf, Shehu Abdullahi, Adeseye Akinsete, Foluke Fasola, Modupe Idowu, Sharon Pennington, Sheinei Alan, Marshall Stagg, Earl Fields, David Archer, Xiufeng Gao, Aliya Zaidi, Patrick Hines, Yuvika Paliwal, Denis Rybin, Eric Zimmerman, Adeyemi Adenola, Mira Pochron, Eleanor Lisbon, Geoffrey Allen
Journal: Blood
Blood (2025) 146 (Supplement 1): 4728.
https://doi.org/10.1182/blood-2025-4728
Published: 2025
Journal Articles

Pharmacological Inhibition of TMPRSS6 Decreases Hemoglobin Concentration and Red Blood Cell (RBC) Hemolysis in a Mouse Model of Sickle Cell Disease

Free
Silvia Giannini, Earl Fields, Jr., Jesse Bueno, Christopher Chambliss, Min Wu, David R Archer
Journal: Blood
Blood (2024) 144 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2024-204708
Published: 2024
Journal Articles

Placental Abnormalities in the Humanized Mouse Model of Sickle Cell Disease

Free
Christopher Chambliss, Elizabeth Manci, Elizabeth Eldeiry, Earl Fields, Jr., Jesse Bueno, Satheesh Chonat, David R Archer
Journal: Blood
Blood (2024) 144 (Supplement 1): 2487.
https://doi.org/10.1182/blood-2024-208162
Published: 2024
Journal Articles

Characterizing Pregnancy Outcomes in a Humanized Mouse Model of Sickle Cell Disease

Free
Christopher Chambliss, Elizabeth Manci, Earl Fields, Jesse Bueno, Adeola Michael, Satheesh Chonat, David R Archer
Journal: Blood
Blood (2023) 142 (Supplement 1): 563.
https://doi.org/10.1182/blood-2023-185898
Published: 2023
Journal Articles

Preliminary Pharmacodynamic Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease

Free
Mira Patel Pochron, Adeseye Michael Akinsete, Shehu Umar Abdullahi, Foluke A Fasola, Modupe Idowu, Sharon Pennington, William B Ershler, Marshall Patrick Stagg, Earl Fields, Morgan Sterling, Satheesh Chonat, Yuvika Paliwal, Karena Kong, David R Archer, Adeyemi Adenola, Eleanor A Lisbon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1155.
https://doi.org/10.1182/blood-2023-188929
Published: 2023
Journal Articles

Improvement in Red Blood Cell Physiology in Children with Sickle Cell Anemia Receiving Voxelotor

Free
Satheesh Chonat, MD, Earl Fields, Hannah Baratz, Amanda Watt, Mira Pochron, PhD, Sandy Dixon, Margaret Tonda, PharmD, Joshua Lehrer-Graiwer, MD MPhil, FACC, Clark Brown, MD PhD, David R. Archer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2281.
https://doi.org/10.1182/blood-2019-129351
Published: 2019