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Dorien Pastoors
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Journal Articles

MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia

Available to Purchase
Brief Report
Dorien Pastoors, Marije Havermans, Roger Mulet-Lazaro, Leonie Smeenk, Sophie Ottema, Claudia Erpelinck-Verschueren, Stanley van Herk, Maikel Anthonissen, Tim Grob, Shruthi Subramanian, Julie A. I. Thoms, John E. Pimanda, Bas J. Wouters, Berna Beverloo, Torsten Haferlach, Claudia Haferlach, Johannes Zuber, Eric Bindels, Ruud Delwel
Journal: Blood
Blood (2025) 146 (25): 3098–3105.
https://doi.org/10.1182/blood.2025028914
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting Super-Enhancers Driving EVI1 Expression in Leukemia By Inhibition of p300/CBP

Free
Dorien Pastoors, Claudia Erpelinck, Stanley Van Herk, Roger Mulet-Lazaro, Marije Havermans, Eric Bindels, Sophie Ottema, Ruud Delwel
Journal: Blood
Blood (2023) 142 (Supplement 1): 710.
https://doi.org/10.1182/blood-2023-181741
Published: 2023
Journal Articles

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA

Free
Dorien Pastoors, Marije Havermans, Remco Hoogenboezem, Roger Mulet-Lazaro, Duncan Brian, Leonie Smeenk, Claudia Erpelinck-Verschueren, Stanley van Herk, Bas Wouters, Jeroen A.A. Demmers, Johannes Zuber, Tariq Enver, Richard WJ Groen, Eric Bindels, Ruud Delwel
Journal: Blood
Blood (2022) 140 (Supplement 1): 83–84.
https://doi.org/10.1182/blood-2022-156994
Published: 2022