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Journal Articles

Cellpolaris: A novel tool to quantify cell polarity reliably at scale in fixed and living cells

Soumen Bera, Jessica Nunes, Shalmali Pendse, Marcus Harrell, Dirk Loeffler

Blood (2025) 146 (Supplement 1): 1382.

https://doi.org/10.1182/blood-2025-1382

Published: 2025

Journal Articles

GPRASP2 maintains hematopoietic stem cell quiescence and self-renewal by receptor-mediated endocytosis

Alanna Van Huizen, Mattieu Zhai, Zakiya Kelley, Emilia Kooienga, Preeti Dabas, Lance Palmer, Kate Tisdale, Dirk Loeffler, Dewmi Rathnayake, Madeleine Rodgers, Ishani Sharma, Antonio Morales-Hernandez, Shannon McKinney-Freeman

Blood (2025) 146 (Supplement 1): 1374.

https://doi.org/10.1182/blood-2025-1374

Published: 2025

Journal Articles

Hematopoietic Stem Cell Function and Differentiation Is Regulated By DCAF7 through Polycomb Repressive Complex 1 (PRC1) Modulation

Johanna Melo-Cardenas, Lavanya Bezavada, Te Ling, Amber Broadhurst, Anitria Cotton, Jeremy Chase Crawford, Amanda Nourse, Vishwajeeth Pagala, Qiong Zhang, Wojciech Rosikiewicz, Hongjian Jin, Dirk Loeffler, John D. Crispino

Blood (2024) 144 (Supplement 1): 1272.

https://doi.org/10.1182/blood-2024-210287

Published: 2024

Journal Articles

CDK6: HSC fate and cell cycle nexus?

Dirk Loeffler

Blood (2024) 144 (2): 126–128.

https://doi.org/10.1182/blood.2024025085

Published: 2024

Journal Articles

HSC aging: a sleeping beauty fairy tale?

Dirk Loeffler

Blood (2023) 141 (16): 1902–1904.

https://doi.org/10.1182/blood.2023019780

Published: 2023

Journal Articles

Asymmetric organelle inheritance predicts human blood stem cell fate

Dirk Loeffler, Florin Schneiter, Weijia Wang, Arne Wehling, Tobias Kull, Claudia Lengerke, Markus G. Manz, Timm Schroeder

Blood (2022) 139 (13): 2011–2023.

https://doi.org/10.1182/blood.2020009778

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

Weijia Wang, Yang Zhang, Philip Dettinger, Andreas Reimann, Tobias Kull, Dirk Loeffler, Markus G. Manz, Claudia Lengerke, Timm Schroeder

Blood (2021) 138 (10): 847–857.

https://doi.org/10.1182/blood.2020008386

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

James Chavez, BS, Jennifer L Rabe, BS, BA, Kelly Higa, MS, Dirk Loeffler, Ahmed Nouraiz, PhD, Taylor Mills, BA, Beau M Idler, Brett M. Stevens, PhD, Courtney Fleenor, PhD, Claus Nerlov, PhD, Hideaki Nakajima, MD, James Hagman, Timm Schroeder, PhD, Hyun Min Kim, PhD, Craig T Jordan, PhD, James DeGregori, Eric Pietras, PhD

Blood (2019) 134 (Supplement_1): 822.

https://doi.org/10.1182/blood-2019-129300

Published: 2019

Journal Articles

Understanding cell fate control by continuous single-cell quantification

Dirk Loeffler, Timm Schroeder

Blood (2019) 133 (13): 1406–1414.

https://doi.org/10.1182/blood-2018-09-835397

Published: 2019

Journal Articles

Inflammatory signals directly instruct PU.1 in HSCs via TNF

Martin Etzrodt, Nouraiz Ahmed, Philipp S. Hoppe, Dirk Loeffler, Stavroula Skylaki, Oliver Hilsenbeck, Konstantinos D. Kokkaliaris, Hans-Michael Kaltenbach, Jörg Stelling, Claus Nerlov, Timm Schroeder

Blood (2019) 133 (8): 816–819.

https://doi.org/10.1182/blood-2018-02-832998

Published: 2019

Includes: Supplemental data

Journal Articles

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Mairi S. Shepherd, Juan Li, Nicola K. Wilson, Caroline A. Oedekoven, Jiangbing Li, Miriam Belmonte, Juergen Fink, Janine C. M. Prick, Dean C. Pask, Tina L. Hamilton, Dirk Loeffler, Anjana Rao, Timm Schröder, Berthold Göttgens, Anthony R. Green, David G. Kent

Blood (2018) 132 (8): 791–803.

https://doi.org/10.1182/blood-2017-12-821066

Published: 2018

Includes: Supplemental data

Journal Articles

Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating

Dirk Loeffler, Weijia Wang, Alois Hopf, Oliver Hilsenbeck, Paul E. Bourgine, Fabian Rudolf, Ivan Martin, Timm Schroeder

Blood (2018) 131 (13): 1425–1429.

https://doi.org/10.1182/blood-2017-07-794131

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

CSF-1–induced Src signaling can instruct monocytic lineage choice

Max Endele, Dirk Loeffler, Konstantinos D. Kokkaliaris, Oliver Hilsenbeck, Stavroula Skylaki, Philipp S. Hoppe, Axel Schambach, E. Richard Stanley, Timm Schroeder

Blood (2017) 129 (12): 1691–1701.

https://doi.org/10.1182/blood-2016-05-714329

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification

Konstantinos D. Kokkaliaris, Erin Drew, Max Endele, Dirk Loeffler, Philipp S. Hoppe, Oliver Hilsenbeck, Bernhard Schauberger, Christoph Hinzen, Stavroula Skylaki, Marina Theodorou, Matthias Kieslinger, Ihor Lemischka, Kateri Moore, Timm Schroeder

Blood (2016) 128 (9): 1181–1192.

https://doi.org/10.1182/blood-2016-03-705590

Published: 2016

Includes: Supplemental data

Journal Articles

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Blood (2015) 126 (23): 2391.

https://doi.org/10.1182/blood.V126.23.2391.2391

Published: 2015

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Cellpolaris: A novel tool to quantify cell polarity reliably at scale in fixed and living cells

GPRASP2 maintains hematopoietic stem cell quiescence and self-renewal by receptor-mediated endocytosis

Hematopoietic Stem Cell Function and Differentiation Is Regulated By DCAF7 through Polycomb Repressive Complex 1 (PRC1) Modulation

CDK6: HSC fate and cell cycle nexus?

HSC aging: a sleeping beauty fairy tale?

Asymmetric organelle inheritance predicts human blood stem cell fate

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

Understanding cell fate control by continuous single-cell quantification

Inflammatory signals directly instruct PU.1 in HSCs via TNF

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating

CSF-1–induced Src signaling can instruct monocytic lineage choice

Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

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American Society of Hematology

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