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Journal Articles

Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia

Cristiana O’Brien, Nirvana Nursimulu, Anit Tyagi, Rachel Culp-Hill, Andrea Arruda, Tracy Murphy, Mark D. Minden, Andrew Kent, Brett Stevens, Daniel A. Pollyea, Kristin Hope, Sushant Kumar, Julie A. Reisz, Angelo D'Alessandro, Courtney L. Jones

Blood (2025) 146 (21): 2589–2596.

https://doi.org/10.1182/blood.2025029132

Published: 2025

Includes: Supplemental data

Journal Articles

Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

Blood blood.2025028933.

https://doi.org/10.1182/blood.2025028933

Published: 2025

Includes: Supplemental data

Journal Articles

Metabolic adaptation of regenerative hematopoiesis depends on docking-independent mitochondrial connexin 43

Abhishek K. Singh, Angelo D’Alessandro, Ashley M. Wellendorf, Daniel Gonzalez-Nieto, Matthew Kofron, Monika Dzieciatkowska, Leo Mejia, Luis C. Barrio, Marie-Dominique Filippi, Jose A. Cancelas

Blood (2025) 146 (19): 2306–2321.

https://doi.org/10.1182/blood.2024028079

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Vi Lam, Tingting Liu, Haifeng Shen, Olga Danilova, Katarzyna Dabrowska, Sonia Rodriguez-Rodriguez, Courtney Jones, Martina Cusan, Angelo D'Alessandro, Lapo Alinari, Lili Wang, Tycel Phillips, Patrick Pirrotte, Zheng Xia, Alexey Danilov

Blood (2025) 146 (Supplement 1): 5087.

https://doi.org/10.1182/blood-2025-5087

Published: 2025

Journal Articles

Lipid uptake via FATP2 enhances CAR-t therapy resistance in B-cell acute lymphoblastic leukemia

Blood (2025) 146 (Supplement 1): 325.

https://doi.org/10.1182/blood-2025-325

Published: 2025

Journal Articles

Bone marrow microenvironment retinoic acid receptor signaling represses multipotential progenitor dependent B cell lymphopoiesis through secretion of resistin

Parash Prasad, Angelo D'Alessandro, Ashley Wellendorf, Leo Mejia, Mercedes Ricote, Nathan Salomonis, Jose Cancelas

Blood (2025) 146 (Supplement 1): 1405.

https://doi.org/10.1182/blood-2025-1405

Published: 2025

Journal Articles

Phosphorylation-induced structural remodeling of band 3 as a driver of metabolic dysfunction in sickle cell disease

Amy Argabright, Shaun Bevers, Aaron Issaian, Angelo D'Alessandro

Blood (2025) 146 (Supplement 1): 2928.

https://doi.org/10.1182/blood-2025-2928

Published: 2025

Journal Articles

CD47 mediates oxygen-responsive activation of RBC eNOS during circulatory transit

Zohreh Safari, Mary Brummet, Stephen Rogers, Paisley Maloney, Daniel Bennett, Tobi Rowden, Aishwarya Anand, Thomas blanpied, Shilpa Dilip Kumar, Giuliano Scarcelli, Yogeshwari Ambekar, Angelo D'Alessandro, Miriam Cortese Krott, Brant Isakson, Luke Dunaway, Allan Doctor

Blood (2025) 146 (Supplement 1): 611.

https://doi.org/10.1182/blood-2025-611

Published: 2025

Journal Articles

Dietary saturated fatty acid composition alters the platelet lipid profile and promotes platelet hyperreactivity

Maria Barrachina, Blen Yohannes, Siobhan Branfield, Isabelle Becker, Virginia Camacho, Daniela Freire, Dong Lee, Maryam Labaf, Daniel Stephenson, Estelle Carminita, Liang Sun, Angelo D'Alessandro, Joseph Italiano, Kellie Machlus

Blood (2025) 146 (Supplement 1): 193.

https://doi.org/10.1182/blood-2025-193

Published: 2025

Journal Articles

Targeting nicotinamide salvage pathway is a unique metabolic vulnerability of high-risk MDS stem cells

Blood (2025) 146 (Supplement 1): 232.

https://doi.org/10.1182/blood-2025-232

Published: 2025

Journal Articles

Long-term mitapivat treatment improves inflammatory pro-fibrotic cardiomyopathy in a murine model of β-thalassemia.

Enrica Federti, Alessandra Ghigo, Tolunay Kavaz, Veronica Riccardi, Richard Pozzetto Huot, Jacopo Ceolan, Simone Villaboni, Angelo D'Alessandro, Federica Logrand, Leonardo Rivadeneyra, Megan Wind-Rotolo, Lucia De Franceschi

Blood (2025) 146 (Supplement 1): 727.

https://doi.org/10.1182/blood-2025-727

Published: 2025

Journal Articles

Perturbation of iNKT differentiation during clonal hematopoiesis from rewiring of inflammation and lipid presentation

Francesca Luca, Alana Franceski, Paran Goel, Brittany Crown, Ashley Connelly, Caroline Ennis, Daniel Phillips, Sajesan Aryal, Valeriya Kuznetsova, Amanda Costa, Molly Boettiger, Angelo D'Alessandro, Robert Welner

Blood (2025) 146 (Supplement 1): 978.

https://doi.org/10.1182/blood-2025-978

Published: 2025

Journal Articles

Lipid deregulation impacts hematopoietic stem cell functions during aging

Devyani Sharma, Juying Xu, Angelo D'Alessandro, Marie-Dominique Filippi

Blood (2025) 146 (Supplement 1): 975.

https://doi.org/10.1182/blood-2025-975

Published: 2025

Journal Articles

A branched chain amino acid rheostat controls hematopoietic stem cell replicative lifespan

Sydney Treichel, James Bartram, Baobao (Annie) Song, Waseem Nasr, Colin Anderson, Juying Xu, Devyani Sharma, Madeline Frangiosa, Andrew Harley, Angelo D'Alessandro, Nathan Salomonis, H. Leighton Grimes, Marie-Dominique Filippi

Blood (2025) 146 (Supplement 1): 1381.

https://doi.org/10.1182/blood-2025-1381

Published: 2025

Journal Articles

Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in trauma patients

Nana Kwame Kwabi Boateng, Riley Marie Wimberley, Jacob P Rose, Angelo D'Alessandro, Mitchell J Cohen, Ernest E Moore, Lauren Schmitt, Lauren Poole, James P. Luyendyk, Kirk C Hansen

Blood blood.2025029458.

https://doi.org/10.1182/blood.2025029458

Published: 2025

Includes: Supplemental data

Journal Articles

Ferroptosis regulates hemolysis in stored murine and human red blood cells

Blood (2025) 145 (7): 765–783.

https://doi.org/10.1182/blood.2024026109

Published: 2025

Includes: Supplemental data

Journal Articles

Low Dose Clodronate Improves Exercise Tolerance, Right Ventricular Function, and Alters Resident Lung Macrophage Phenotypes

Christina Lisk, Francesca I Cendali, Delany Swindle, Gemlyn George, Kathryn Louise Hassell, Rachelle Nuss, Angelo D'Alessandro, Paul Buehler, David Irwin

Blood (2024) 144 (Supplement 1): 3874.

https://doi.org/10.1182/blood-2024-211429

Published: 2024

Journal Articles

Bone Marrow Adipocyte Secreted Resistin Is a Positive Regulator of Long-Term Hematopoietic Stem Cell Engraftment and Myelopoiesis

Parash Prasad, Angelo D'Alessandro, Grace Oh, Ashley Wellendorf, Mercedes Ricote, Nathan Salomonis, Jose Cancelas

Blood (2024) 144 (Supplement 1): 560.

https://doi.org/10.1182/blood-2024-210644

Published: 2024

Journal Articles

Oxygen Responsive Myosin Activation Governs Oscillatory Piezo1 Signaling in RBCs during Circulatory Transit

Zohreh Safari, Stephen C Rogers, Mary E Brummet, Daniel Bennett, Emioluwa Odunaiya, Adaora Eziemefe, Jacqueline Nguyen, Sarah Enjati, Olivia Conelius, Angelo D'Alessandro, Aaron Issaian, Monika monikA.dzieciatkow, Fabia Gamboni, Jason Held, Isakson Brant, Luke S Dunaway, Miriam Cortese Krott, Allan Doctor

Blood (2024) 144 (Supplement 1): 2453.

https://doi.org/10.1182/blood-2024-207417

Published: 2024

Journal Articles

Peripheral Blood Macrophages (PBMCs) from Adults with Sickle Cell Disease Have a Unique Phenotype

Christina Lisk, Francesca I Cendali, Delany Swindle, Gemlyn George, Kathryn Louise Hassell, Rachelle Nuss, Paul Buehler, Angelo D'Alessandro, David Irwin

Blood (2024) 144 (Supplement 1): 1143.

https://doi.org/10.1182/blood-2024-211244

Published: 2024

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Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia

Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

Metabolic adaptation of regenerative hematopoiesis depends on docking-independent mitochondrial connexin 43

Selective targeting of sumoylation disrupts mitochondrial homeostasis via TRAP1 to suppress growth of non-Hodgkin lymphoma (NHL) B-cells

Lipid uptake via FATP2 enhances CAR-t therapy resistance in B-cell acute lymphoblastic leukemia

Bone marrow microenvironment retinoic acid receptor signaling represses multipotential progenitor dependent B cell lymphopoiesis through secretion of resistin

Phosphorylation-induced structural remodeling of band 3 as a driver of metabolic dysfunction in sickle cell disease

CD47 mediates oxygen-responsive activation of RBC eNOS during circulatory transit

Dietary saturated fatty acid composition alters the platelet lipid profile and promotes platelet hyperreactivity

Targeting nicotinamide salvage pathway is a unique metabolic vulnerability of high-risk MDS stem cells

Long-term mitapivat treatment improves inflammatory pro-fibrotic cardiomyopathy in a murine model of β-thalassemia.

Perturbation of iNKT differentiation during clonal hematopoiesis from rewiring of inflammation and lipid presentation

Lipid deregulation impacts hematopoietic stem cell functions during aging

A branched chain amino acid rheostat controls hematopoietic stem cell replicative lifespan

Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in trauma patients

Ferroptosis regulates hemolysis in stored murine and human red blood cells

Low Dose Clodronate Improves Exercise Tolerance, Right Ventricular Function, and Alters Resident Lung Macrophage Phenotypes

Bone Marrow Adipocyte Secreted Resistin Is a Positive Regulator of Long-Term Hematopoietic Stem Cell Engraftment and Myelopoiesis

Oxygen Responsive Myosin Activation Governs Oscillatory Piezo1 Signaling in RBCs during Circulatory Transit

Peripheral Blood Macrophages (PBMCs) from Adults with Sickle Cell Disease Have a Unique Phenotype

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