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Journal Articles

First report of the GIMEMA INO-first multicenter observational study analyzing infective and non-infective complications in patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with inotuzumab ozogamicin.

Free
Anna Candoni, Alfonso Piciocchi, Luana Fianchi, Valeria Sargentini, Nicola Stefano Fracchiolla, Giovanni Marsili, Mario Tiribelli, Chiara Cattaneo, Cristina Papayannidis, Crescenza Pasciolla, Angelo Michele Carella, Massimiliano Bonifacio, Maria Ilaria Del Principe, Francesca Farina, Maria Paola Martelli, Monica Fumagalli, Nicola Di Renzo, Francesco Marchesi, Agostino Tafuri, Claudia Maria Basilico, Cristina Skert, Alessandro Busca, Livio Pagano
Journal: Blood
Blood (2025) 146 (Supplement 1): 5102.
https://doi.org/10.1182/blood-2025-5102
Published: 2025
Journal Articles

Brentuximab vedotin (Bv)+AVD efficacy is influenced by interim PET, age, ECOG performance status and CIRS-g in previously untreated patients with stage IV classical Hodgkin lymphoma: An Italian real-life multicentric study

Free
Giovanni Manfredi Assanto, Silvia Sorella, Giovanni Marsili, Nadia Messina, Gianna Maria D'Elia, Alessandro Cellini, Andrea Visentin, Annagiulia Zizzari, Daniela Renzi, Ombretta Annibali, Valeria Tomarchio, Chiara Togni, Maria Paola Bianchi, Mariella Lo Schirico, Candida Vitale, Natalia Cenfra, Emanuele Cencini, Erica Finolezzi, Benedetta Bianchi, Giada Pacitto, Mauro Passucci, Giorgia Annechini, Jenni Baliosi, Roberta Battistini, M. Christina Cox, Marta Coscia, Alessandro Pulsoni, Agostino Tafuri, Massimiliano Postorino, Luigi Rigacci, Livio Trentin, Stefan Hohaus, Alfonso Piciocchi, Maurizio Martelli, Ilaria Del Giudice
Journal: Blood
Blood (2025) 146 (Supplement 1): 5402.
https://doi.org/10.1182/blood-2025-5402
Published: 2025
Journal Articles

The prognostic value for survival of frailty and patient-reported outcomes in relapsed/refractory multiple myeloma: Results from a prospective multicenter observational study

Free
Fabio Efficace, Gianluca Gaidano, Pasquale Niscola, Serena Puglia, Francesco Sparano, Katia Codeluppi, Elisabetta Antonioli, Catello Califano, Lajos Floro, Ombretta Annibali, Claudio Fozza, Agostino Tafuri, Patrizio Mazza, Leonardo Potenza, Marco Vignetti, Michele Cavo, Maria Teresa Petrucci
Journal: Blood
Blood (2025) 146 (Supplement 1): 138.
https://doi.org/10.1182/blood-2025-138
Published: 2025
Journal Articles

International, prospective study comparing nilotinib versus imatinib with early switch to nilotinib to obtain sustained treatment-free remission (TFR) in patients with chronic myeloid leukemia: The tfr rate at the end of follow-up

Free
Massimo Breccia, Fausto Castagnetti, Elisabetta Abruzzese, Renato Bassan, Gianni Binotto, Massimiliano Bonifacio, Giovanni Caocci, Isabella Capodanno, Francesco Cavazzini, Giuseppe Cimino, Paola Fazi, Antonella Gozzini, Alessandra Iurlo, Jeroen Janssen, Monia Lunghi, Roberto Marasca, Bruno Martino, Monica Messina, Francesco Muriano, Francesca Paoloni, Alfonso Piciocchi, Gianantonio Rosti, Antonella Russo Rossi, Giuseppe Saglio, Simona Sica, Simona Soverini, Agostino Tafuri, Daniele Vallisa, Peter Westerweel, Fabrizio Pane
Journal: Blood
Blood (2025) 146 (Supplement 1): 905.
https://doi.org/10.1182/blood-2025-905
Published: 2025
Journal Articles

Post-transplant lymphoproliferative disorders in adult transplant recipients: Preliminary results of the multicenter italian FIL_PTLD study

Free
Chiara Consoli, Periana Minga, Andrea Evangelista, Anna Maria Barbui, Francesca Gaia Rossi, Alessandro Re, Dario Marino, Emanuele Ravano, Federico Erbella, Monica Rondi, Nicolò Rampi, Pier Luigi Zinzani, Chiara Cattaneo, Barbara Botto, Jacopo Olivieri, Silvia Finotto, Luigi Petrucci, Alessia Castellino, Marcello Riva, Benedetta Puccini, Emanuele Cencini, Agostino Tafuri, Michele Spina, Ombretta Annibali, Luca Arcaini, Benedetto Bruno, Federica Cavallo
Journal: Blood
Blood (2025) 146 (Supplement 1): 1890.
https://doi.org/10.1182/blood-2025-1890
Published: 2025
Journal Articles

Polycythemia Vera in Patients Aged > 80 Years: Real-Life Experience of the NPM Ph Negative Latial Group

Free
Caterina Tatarelli, Massimo Breccia, Michelina Santopietro, Katia Paciaroni, Ambra Di Veroli, Luca Maurillo, Atelda Romano, Alessandro Andriani, Agostino Tafuri, Roberto Latagliata
Journal: Blood
Blood (2024) 144 (Supplement 1): 6675.
https://doi.org/10.1182/blood-2024-207330
Published: 2024
Journal Articles

Baseline Characteristics from Arise Study, an Italian Non-Interventional Study Assessing the Real-World Use of Acalabrutinib in the Treatment of Patients with Chronic Lymphocytic Leukemia (CLL)

Free
Francesca Romana Mauro, Andrea Visentin, Luca Laurenti, Susanna Gallo, Vincenzo Pavone, Paolo Nicoli, Massimiliano Postorino, Ilaria Scortechini, Lydia Scarfo, Myriam Foglietta, Chiara Borella, Gaetano Palumbo, Nicola Di Rienzo, Monica Tani, Agostino Tafuri, Paolo Sportoletti, Potito Rosario Scalzulli, Elsa Pennese, Domenico Pastore, Cristina Pasquini, Luigi Malandruccolo, Ambra Di Veroli, Gaetano De Santis, Gioacchino Catania, Anna Tamburini, Caterina Stelitano, Fabrizio Pane, Pellegrino Musto, Massimo Magagnoli, Giovanni D'Arena, Daniele Caracciolo, Deborah Bongiovanni, Gianluigi Reda, Claudia Padrone, Massimo Gentile
Journal: Blood
Blood (2024) 144 (Supplement 1): 7747.
https://doi.org/10.1182/blood-2024-199041
Published: 2024
Journal Articles

ASXL1 Mutations at Diagnosis Did Not Impact on the Depth of Molecular Response (MR) and on Treatment-Free Remission (TFR) Eligibility in Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Patients (pts) Receiving either Nilotinib (NIL) First-Line or Imatinib (IM) with Early Switch to NIL in Case of No Optimal Response in the SUSTRENIM Clinical Trial

Free
Simona Soverini, Sara De Santis, Cecilia Monaldi, Manuela Mancini, Valentina Giai, Marco Cerrano, Isabella Capodanno, Massimiliano Bonifacio, Elisabetta Abruzzese, Alessandra Iurlo, Fausto Castagnetti, Rosaria Sancetta, Luciano Levato, Carmen Fava, Mario Tiribelli, Francesco Cavazzini, Maria Cristina Miggiano, Niccolò Bolli, Agostino Tafuri, Alessandro Lucchesi, Daniele Vallisa, Monia Lunghi, Caterina Musolino, Samantha Bruno, Cristina Mosca, Mauro Ciriello, Giovanni Marsili, Alfonso Piciocchi, Paola Fazi, Michele Cavo, Jeroen J.W.M. Janssen, Peter E. Westerweel, Fabrizio Pane
Journal: Blood
Blood (2024) 144 (Supplement 1): 3158.
https://doi.org/10.1182/blood-2024-205465
Published: 2024
Journal Articles

CD49d Expression Is Included in a Revised 4-Factor Model Predicting Outcome in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib: A Multi-Center Real-World Experience

Free
Riccardo Bomben, Antonella Zucchetto, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Erika Tissino, Francesca Rossi, Filippo Vit, Tamara Bittolo, Robel Papotti, Federico Pozzo, Annalisa Gaglio, Massimo Degan, Jerry Polesel, Roberto Marasca, Gianluigi Reda, Andrea Visentin, Riccardo Moia, Idanna Innocenti, Candida Vitale, Roberta Murru, Marzia Varettoni, Agostino Tafuri, Francesco Zaja, Massimiliano Postorino, Enrica Antonia Martino, Adalgisa Condolucci, Davide Rossi, Antonio Cuneo, Francesco Di Raimondo, Paolo Sportoletti, Ilaria Del Giudice, Robin Foa, Francesca Romana Mauro, Marta Coscia, Luca Laurenti, Gianluca Gaidano, Livio Trentin, Maria Ilaria Del Principe, Massimo Gentile, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 3281.
https://doi.org/10.1182/blood-2023-174897
Published: 2023
Journal Articles

Copanlisib in Combination with Rituximab and Bendamustine for Transplant-Ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients: Results from the Phase II Multicenter Fil_Copa-Rb Trial from Fondazione Italiana Linfomi (FIL)

Free
Pio Manlio Mirko Frascione, Mattia Novo, Alessia Castellino, Luigi Marcheselli, Samantha Deianira Dattoli, Alessandra Tucci, Guido Gini, Giuseppe Tarantini, Donato Mannina, Annalisa Arcari, Roberta Martiniani, Elisabetta Scarpa, Dario Marino, Michele Spina, Ausilia Giuseppa Gorgone, Nicola Di Renzo, Salvatrice Mancuso, Luigi Petrucci, Agostino Tafuri, Umberto Vitolo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1728.
https://doi.org/10.1182/blood-2023-184718
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients into Novel Categories with Different Risk of Early Treatment

Free
Federico Pozzo, Francesca Cuturello, Edith Villegas Garcia, Francesca Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni Francesco D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Alessio Ansuini, Chris Fegan, Chris Pepper, Andrea Pepper, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 1892.
https://doi.org/10.1182/blood-2023-177884
Published: 2023
Journal Articles

Patients' Perception of Usability and Utility of a Digital Health Tool for Electronic Patient-Reported Outcomes Monitoring in Real-Life Hematology Practice: Evidence from the Gimema-Alliance Platform

Free
Fabio Efficace, Mario Luppi, Leonardo Potenza, Francesco Sparano, Giovanni Caocci, Francesca Fazio, Massimo Breccia, Maria Teresa Petrucci, Andrea Patriarca, Thomas Baldi, Michelina Santopietro, Roberta Battistini, Agostino Tafuri, Gloria Margiotta Casaluci, Elisabetta Colaci, Davide Giusti, Valeria Pioli, Paolo De Fabritiis, Nicolina Rita Ardu, Pasquale Niscola, Olga Mulas, Claudio Fozza, Sergio Siragusa, Salvatrice Mancuso, Paola Boggione, Lorenzo De Paoli, Anna Paola Leporace, Maria Paola Bianchi, Ida Carmosino, Claudio Cartoni, Alice Di Rocco, Isabella Capodanno, Massimo Pini, Alessandra Romano, Paola Fazi, Marco Vignetti
Journal: Blood
Blood (2023) 142 (Supplement 1): 3714.
https://doi.org/10.1182/blood-2023-180574
Published: 2023
Journal Articles

International, Prospective Study Comparing Nilotinib Versus Imatinib with Early Switch to Nilotinib to Obtain Sustained Treatment-Free Remission in Patients with Chronic Myeloid Leukemia (SUSTRENIM trial): Analysis of the Eligibility to Treatment Discontinuation

Free
Fabrizio Pane, Fausto Castagnetti, Alfonso Piciocchi, Elisabetta Abruzzese, Renato Bassan, Gianni Binotto, Massimiliano Bonifacio, Giovanni Caocci, Francesco Cavazzini, Giuseppe Cimino, Antonella Gozzini, Monia Lunghi, Roberto Marasca, Bruno Martino, Francesco Muriano, Gianantonio Rosti, Antonella Russo Rossi, Simona Sica, Agostino Tafuri, Daniele Vallisa, Monica Messina, Francesca Paola Paoloni, Paola Fazi, Peter E Westerweel, Jeroen J.W.M. Janssen, Giuseppe Saglio, Massimo Breccia
Journal: Blood
Blood (2023) 142 (Supplement 1): 3169.
https://doi.org/10.1182/blood-2023-182220
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Free
Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

Reappearance of CXCR4 dim /CD5 bright Proliferative Fraction Associates with BTK Mutations and Anticipates Progression in Ibrutinib-Treated CLL

Free
Federico Pozzo, Gabriela Forestieri, Filippo Vit, Erika Tissino, Tamara Bittolo, Robel Papotti, Annalisa Gaglio, Lodovico Terzi Di Bergamo, Agostino Steffan, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4627.
https://doi.org/10.1182/blood-2023-174906
Published: 2023
Journal Articles

Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial

Free
Clinical Trials & Observations
Naval G. Daver, Monique Dail, Jacqueline S. Garcia, Brian A. Jonas, Karen W. L. Yee, Kevin R. Kelly, Norbert Vey, Sarit Assouline, Gail J. Roboz, Stefania Paolini, Daniel A. Pollyea, Agostino Tafuri, Joseph M. Brandwein, Arnaud Pigneux, Bayard L. Powell, Pierre Fenaux, Rebecca L. Olin, Giuseppe Visani, Giovanni Martinelli, Maika Onishi, Jue Wang, Weize Huang, Cherie Green, Marion G. Ott, Wan-Jen Hong, Marina Y. Konopleva, Michael Andreeff
Journal: Blood
Blood (2023) 141 (11): 1265–1276.
https://doi.org/10.1182/blood.2022016362
Published: 2023
Includes: Supplemental data
Journal Articles

Impact of COVID-19 Pandemic Waves on Outcomes of Patients with Previously Untreated Advanced Follicular Lymphoma Enrolled in the Urban Ambispective Study in Italy

Free
Antonio Pinto, Emanuele Guardalben, Marica Battista, Giulia Chiara Gazzoli, Michele Merli, Annalisa Chiarenza, Tommasina Perrone, Attilio Guarini, Nicola Di Renzo, Carlo Visco, Agostino Tafuri, Roberta Murru, Felicetto Ferrara, Jacopo Olivieri, Attilio Olivieri, Andrés J M Ferreri, Marco Ladetto, Pier Luigi Zinzani, Luca Arcaini, Giuseppe Gritti
Journal: Blood
Blood (2022) 140 (Supplement 1): 6504–6506.
https://doi.org/10.1182/blood-2022-166486
Published: 2022
Journal Articles

Remarkable Remission Rate and Long-Term Efficacy of Upfront Metronomic Chemotherapy in Elderly/FRAIL Patients, with Diffuse Large B-Cell Lymphoma

Free
M. Christina Cox, Sabrina Pelliccia, Paola Orlandi, Arianna Di Napoli, Gerardo Musuraca, Caterina Patti, Maria Paola Bianchi, Matteo Caridi, Marta Banchi, Roberta Battistini, Tiziana Lanzolla, Agostino Tafuri, Guido Bocci
Journal: Blood
Blood (2022) 140 (Supplement 1): 3796–3797.
https://doi.org/10.1182/blood-2022-165379
Published: 2022
Journal Articles

The CXCR4 dim /CD5 bright Proliferative Fraction Reappears in Relapsed CLL Under Ibrutinib, Enriched in BTK Mutations

Free
Federico Pozzo, Gabriela Forestieri, Giulia Ianna, Filippo Vit, Erika Tissino, Tamara Bittolo, Lodovico Terzi Di Bergamo, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4103–4104.
https://doi.org/10.1182/blood-2022-159947
Published: 2022
Journal Articles

Real-World Outcome of Treatment with Single-Agent Ibrutinib in Patients with Chronic Lymphocytic Leukemia: Results from the Italian Study Evidence

Free
Stefano Molica, Potito Rosario Scalzulli, Lydia Scarfò, Attilio Guarini, Roberta Murru, Paolo Sportoletti, Ferdinando Frigeri, Francesco Albano, Nicola Di Renzo, Alessandro Sanna, Idanna Innocenti, Massimo Massaia, Marta Coscia, Elsa Pennese, Caterina Patti, Gianluigi Reda, Agostino Tafuri, Giulia Regazzoni, Michele Di Candia, Francesca Romana Mauro
Journal: Blood
Blood (2022) 140 (Supplement 1): 4178–4180.
https://doi.org/10.1182/blood-2022-166140
Published: 2022