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Issue Archive
December 2025
Table of Contents
CELLULAR IMMUNOTHERAPY
Donor lymphocyte infusions after HCT are associated with low risk of graft-versus-host disease in pediatric and young adult patients
Shruthi Suryaprakash,Yilun Sun,Dinesh Keerthi,Amr Qudeimat,Ali Suliman,Aimee C. Talleur,Esther Obeng,Ewelina Mamcarz,Renee Madden,Rebecca Epperly,Senthil V. Bhoopalan,Swati Naik,Caitlin C. Zebley,M. Paulina Velasquez,Paula Arnold,Li Tang,Stephen Gottschalk,Brandon M. Triplett,Akshay Sharma
Viral vector-free generation of orthogonal IL-2–responsive CAR T cells through gene editing of IL-2 and its receptor
Qian Zhang,Yihao Wu,Jingyi Yang,Kevin Zhou,Eric Nigel Ebenezer Anand Manoharan,Tyra Wentz,Leon Su,Alvin Yu,Hong-Yi Wang,Laurakay Bruhn,Israel Steinfeld,Nicolas Gonzalez,Edward Z. Song,Yunlin Zhang,Morgan E. Hresko,Daniel E. Ryan,Nils W. Engel,Selene Nunez-Cruz,Carl H. June,K. Christopher Garcia,Michael C. Milone
Utility of neurotoxicity investigations in CD19 and BCMA CART recipients with ICANS
Lauren N. Scott,Benjamin Hane,William Wesson,Pilar Thangwaritorn,Raeef Rahman,Marc Hoffmann,Forat Lutfi,Zahra Mahmoudjafari,Sunil Abhyankar,Dinesh Pal Mudaranthakam,Muhammad Umair Mushtaq,Joseph McGuirk,Al-Ola Abdallah,Muhammad Mahdi Nashatizadeh,Nausheen Ahmed
GENE THERAPY
IMMUNOBIOLOGY
NONCELLULAR IMMUNOTHERAPY
Low-dose nivolumab and lenalidomide in relapsed/refractory Hodgkin lymphoma: a single-arm phase 2 trial
Anu Korula,Uday Kulkarni,Arun Kumar Arunachalam,Phaneendra Datari,Aswin Anand Pai,Sumith Mathew,Fouzia Nambiatheyil Aboobacker,Sushil Selvarajan,Sharon Lionel,Kavitha Lakshmi,Aby Abraham,Biju George,Poonkuzhali Balasubramanian,Vikram Mathews
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Cover Image
Cover Image
Heat map shows the differences in effects on CD3+ protein expression by exportin 1 inhibitor selinexor (SEL) cotherapy and the response status. Columns represent the z score–scaled normalized expressions of the indicated proteins in each posttreatment sample. Annotation tracks indicate the SEL combination therapy arm and patient response status at the time of biopsy. See the article by Kang et al.
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