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Lucie Broskevičová
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Journal Articles

Selective depletion of B-cell subsets underlies increased risk of infection in MM patients treated with anti-BCMA vs -GPRC5D bsAbs

Open Access
Tomas Jelinek, David Žihala, Aintzane Zabaleta, Ioannis V Kostopoulos, Ondrej Soucek, Ondrej Venglar, Cristina Moreno, Despina Fotiou, Eva Radova, Luis-Esteban Tamariz-Amador, Foteini Theodorakakou, Ludmila Muronova, Andrea Manubens, Ourania Tsitsilonis, Tereza Popková, Carmen Gonzalez, Anjana Anilkumar Sithara, Francesco Corrado, Nayda Bidikian, Camila Guerrero, Veronika Kapustova, Daniel Bilek, Patrick Ryan Hagner, Marta Larrayoz, Jose A Martínez-Climent, Lucie Broskevičová, Jana Mihalyova, Maximillian Merz, Tereza Sevcikova, Irene M. Ghobrial, Jesús F. San-Miguel, Meletios A Dimopoulos, Paula Rodriguez-Otero, Jakub Radocha, Efstathios Kastritis, Bruno Paiva, Roman Hajek
Journal: Blood
Blood blood.2025029572.
https://doi.org/10.1182/blood.2025029572
Published: 2025
Includes: Supplemental data
Journal Articles

Longitudinal immune monitoring in patients treated with CD19 and BCMA CAR-T cells using standardized 8‑color flow cytometry panel reveals substantial differences among products kinetics and persistence

Free
Ondrej Venglar, Viera Hrabcakova, Ondrej Soucek, Kamila Kutejova, David Žihala, Jana Mihalyova, Michaela Hornakova, Tereza Sevcikova, Lucie Broskevicova, Lenka Janska Vojtkova, Marek Borsky, Jakub Radocha, Pavel Zak, Michael Doubek, Tomas Kalina, Roman Hajek, David Belada, Frantisek Folber, Tomas Jelinek
Journal: Blood
Blood (2025) 146 (Supplement 1): 5721.
https://doi.org/10.1182/blood-2025-5721
Published: 2025
Journal Articles

High-dimensional profiling reveals predominant depletion of NK cell effector phenotypes in relapsed/refractory multiple myeloma patients treated with anti-CD38 therapy

Free
Ondrej Venglar, Daniel Bilek, Eva Radova, Veronika Kapustova, Marketa Kudelkova, Lucie Broskevicova, Karina Merendova, Jan Vrana, Tereza Popkova, Ludmila Muronova, Jana Mihalyova, Michael Durante, Juli Bago, Benjamin Diamond, Michal Simicek, Brian Walker, Tereza Sevcikova, David Žihala, Ola Landgren, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2025) 146 (Supplement 1): 5720.
https://doi.org/10.1182/blood-2025-5720
Published: 2025
Journal Articles

Biology of circulating tumor cells (CTCs) in multiple myeloma (MM): Comparative transcriptomic profiling reveals egression-associated changes related to CTC burden

Free
Daniel Bilek, Eva Radova, Veronika Kapustova, Ondrej Venglar, Serafim Nenarokov, Lucie Broskevicova, Jan Vrana, Marketa Kudelkova, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Michael Durante, Benjamin Diamond, Michal Simicek, Juli Bago, David Žihala, Tereza Sevcikova, Ola Landgren, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2025) 146 (Supplement 1): 3927.
https://doi.org/10.1182/blood-2025-3927
Published: 2025
Journal Articles

Insights into Biological Mechanisms Responsible for Egression of Circulating Tumor Plasma Cells (CTCs) in Multiple Myeloma

Free
Tomas Jelinek, Serafim Nenarokov, Tereza Sevcikova, Eva Radova, Ondrej Venglar, Veronika Kapustova, Lucie Broskevicova, Jan Vrana, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Michal Simicek, Bachisio Ziccheddu, Benjamin Diamond, Francesco Maura, Ola Landgren, David Zihala, Roman Hájek
Journal: Blood
Blood (2024) 144 (Supplement 1): 3270.
https://doi.org/10.1182/blood-2024-206825
Published: 2024
Journal Articles

Predictive Value of Clonal Plasma Cells in Autografts Assessed By Next Generation Flow Cytometry on Pre-Transplant Bone Marrow MRD in Multiple Myeloma Patients

Free
Ondrej Venglar, Eva Radova, David Zihala, Ivana Tvrda, Ludmila Muronova, Veronika Kapustova, Lucie Broskevicova, Jan Vrana, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Tereza Sevcikova, Michal Kascak, Milan Navratil, Zdenek Koristek, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1962.
https://doi.org/10.1182/blood-2024-204692
Published: 2024
Journal Articles

Composition and Fitness of T and NK Cells in Extramedullary Myeloma Tumor Microenvironment

Free
David Zihala, Anjana Anilkumar Sithara, Veronika Kapustova, Ondrej Venglar, Eva Radova, Lucie Broskevicova, Jan Vrana, Serafim Nenarokov, Daniel Bilek, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Sandra Charvatova, Kamlesh Bisht, Hongfang Wang, Helgi Van de Velde, Michal Simicek, Tereza Sevcikova, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1887.
https://doi.org/10.1182/blood-2024-206798
Published: 2024
Journal Articles

Depletion of Mature B Cells and of Normal Plasma Cells (PC) behind the Higher Incidence of Infections after Anti-BCMA VS Anti-GPRC5D Bispecific Antibodies (bsAb) in Relapsed Refractory Multiple Myeloma (RRMM)

Free
Tomas Jelinek, David Zihala, Aintzane Zabaleta, Ioannis V Kostopoulos, Ondrej Soucek, Ondrej Venglar, Cristina Moreno, Despina Fotiou, Eva Radova, Luis-Esteban Tamariz-Amador, Foteini Theodorakakou, Ludmila Muronova, Andrea Manubens, Ourania Tsitsilonis, Tereza Popkova, Lucie Broskevicova, Jana Mihalyova, Tereza Sevcikova, Jesús F. San-Miguel, Meletios Dimopoulos, Paula Rodríguez-Otero, Jakub Radocha, Efstathios Kastritis, Bruno Paiva, Roman Hajek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1934.
https://doi.org/10.1182/blood-2024-205481
Published: 2024
Journal Articles

Pathogenesis of Extramedullary Multiple Myeloma: From Resistance to Identification of Novel Therapeutic Targets

Free
Tomas Jelinek, David Zihala, Tereza Sevcikova, Veronika Kapustova, Hana Sahinbegovic, Anjana Anilkumar Sithara, Tereza Popkova, Hana Plonkova, Lucie Broskevicova, Jan Vrana, Vladimir Zidlik, Martin Havel, Zdenek Koristek, Juli R. Bago, Michal Simicek, Roman Hajek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2680.
https://doi.org/10.1182/blood-2021-150876
Published: 2021
Journal Articles

Effect of Daratumumab-Containing Induction on CD34+ Hematopoietic Stem Cells before Autologous Stem Cell Transplantation in Multiple Myeloma

Free
Ondrej Venglar, Tereza Sevcikova, Anjana Anilkumar Sithara, Veronika Kapustova, Jan Vrana, David Zihala, Ludmila Muronova, Lucie Huvarova, Lucie Broskevicova, Michal Simicek, Zdenek Koristek, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2764.
https://doi.org/10.1182/blood-2021-150360
Published: 2021
Journal Articles

Identification of Molecular Mechanisms Responsible for the Development of Extramedullary Disease in Myeloma and Potential Novel Therapeutic Targets Using Transcriptomic and Exome Profiling

Free
David Zihala, Tereza Sevcikova, Michal Simicek, Tereza Popkova, Hana Plonkova, Lucie Broskevicova, Jan Vrana, Juli R. Bago, Roman Hajek, Giovanni Stracquadanio, Tomas Jelinek
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-142300
Published: 2020