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David L Wiest
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Journal Articles

Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1–mediated immune suppression during GVHD

Free
Ying Wang, Shan He, Gennaro Calendo, Tien Bui, Yuanyuan Tian, Che Young Lee, Yan Zhou, Xin Zhao, Ciril Abraham, Wenbin Mo, Mimi Chen, Ruqayyah Sanders-Braggs, Jozef Madzo, Jean-Pierre Issa, Elizabeth O. Hexner, David L. Wiest, Ran Reshef, Hai-Hui Xue, Yi Zhang
Journal: Blood
Blood (2024) 143 (2): 166–177.
https://doi.org/10.1182/blood.2023021126
Published: 2024
Includes: Supplemental data
Journal Articles

Divergent Functions of ERK2 Substrate Binding Modalities in Myeloproliferative Neoplasm

Free
Billy Truong, Monika Toma, Yong Zhang, Susan Shinton, Muheng Li, Xiang Hua, Dietmar Kappes, Paul Shapiro, Tomasz Skorski, David L. Wiest
Journal: Blood
Blood (2023) 142 (Supplement 1): 996.
https://doi.org/10.1182/blood-2023-191180
Published: 2023
Journal Articles

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Free
Yong Zhang, Billy Truong, Shawn P. Fahl, Esteban Martinez, Kathy Q. Cai, Essel D. Al-Saleem, Yulan Gong, Dan A. Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Steven Fletcher, Dietmar Kappes, Stephen M. Sykes, Paul Shapiro, David L. Wiest
Journal: Blood
Blood (2022) 140 (4): 359–373.
https://doi.org/10.1182/blood.2021013068
Published: 2022
Includes: Supplemental data
Journal Articles

Ribosomal Protein Rpl22 Regulates Development and Transformation Via Altering RNA Processing

Free
Minshi Wang, PhD, Zheng Ser, Shuyun Rao, PhD, Shawn Fahl, Yong Zhang, Suraj Peri, PhD, Alex Kentsis, MD PhD, David L Wiest, PhD
Journal: Blood
Blood (2016) 128 (22): 3878.
https://doi.org/10.1182/blood.V128.22.3878.3878
Published: 2016
Journal Articles

Ribosomal Protein L22 Loss Predisposes Stem Cells to Transformation By Altering Metabolism

Free
Bryan Harris, BS, Shawn Fahl, Jaqueline Perrigoue, Stephen M. Sykes, PhD, Amit Verma, MD, David L Wiest, PhD
Journal: Blood
Blood (2016) 128 (22): 2733.
https://doi.org/10.1182/blood.V128.22.2733.2733
Published: 2016
Journal Articles

Rpl22 Deficiency Predisposes Hematopoietic Stem and Progenitor Cells to Leukemogenesis

Free
Bryan Harris, BS, Jaqueline Perrigoue, Rachel M. Kessel, MD, Shawn Fahl, Stephen Matthew Sykes, PhD, Amit Verma, MD, David L. Wiest, PhD
Journal: Blood
Blood (2015) 126 (23): 899.
https://doi.org/10.1182/blood.V126.23.899.899
Published: 2015
Journal Articles

C-Jun Regulates ER Stress Signaling to Promote Chemotherapy Resistance in Acute Myeloid Leukemia

Free
Chun Zhou, PhD, Daniela Di Marcantonio, PhD, Esteban Martinez, Nehal Solanki-Patel, Suraj Peri, PhD, Claudia Scholl, Stefan Fröhling, David L. Wiest, PhD, Stephen Matthew Sykes, PhD
Journal: Blood
Blood (2015) 126 (23): 2464.
https://doi.org/10.1182/blood.V126.23.2464.2464
Published: 2015
Journal Articles

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B

Free
Shuyun Rao, Sang-Yun Lee, Alejandro Gutierrez, Jacqueline Perrigoue, Roshan J. Thapa, Zhigang Tu, John R. Jeffers, Michele Rhodes, Stephen Anderson, Tamas Oravecz, Stephen P. Hunger, Roman A. Timakhov, Rugang Zhang, Siddharth Balachandran, Gerard P. Zambetti, Joseph R. Testa, A. Thomas Look, David L. Wiest
Journal: Blood
Blood (2012) 120 (18): 3764–3773.
https://doi.org/10.1182/blood-2012-03-415349
Published: 2012
Includes: Supplemental data
Journal Articles

T − B + NK + severe combined immunodeficiency caused by complete deficiency of the CD3ζ subunit of the T-cell antigen receptor complex

Free
Clinical Trials & Observations
Joseph L. Roberts, Jens Peter H. Lauritsen, Myriah Cooney, Roberta E. Parrott, Elisa O. Sajaroff, Chan M. Win, Michael D. Keller, Jeffery H. Carpenter, Juan Carabana, Michael S. Krangel, Marcella Sarzotti, Xiao-Ping Zhong, David L. Wiest, Rebecca H. Buckley
Journal: Blood
Blood (2006) 109 (8): 3198–3206.
https://doi.org/10.1182/blood-2006-08-043166
Published: 2006