Arterial occlusion model. Mice received vehicle (n = 6), GPVI-Fc (4 mg/kg, n = 7), GPVI-Fc* (4 mg/kg, n = 4), or JAQ1 (2 mg/kg, n = 6), and thrombosis was induced in the aorta by one firm compression with a forceps. Blood flow was monitored with an ultrasonic flow probe until complete occlusion. The experiment was stopped after 30 minutes. Each symbol represents one individual.