![Figure 6. Effect of DTT on KCC activation by cell swelling in SS RBCs. (A) Rb influx activated by pH in SS RBCs with (•) and without (♦) preincubation with DTT (10 mM). DTT was present at 1 mM during nystatin treatment and Rb influx measurement. Data represent 4 independent experiments. (B) Normalized fluxes using maximal volume-stimulated flux (MCHC < 270 g/L [27 g/dL]) of control or DTT-treated SS RBCs. (C) Regulatory volume decrease in SS reticulocytes induced by cell swelling (to MCHC of 260 g/L [26 g/dL]) with and without DTT (n = 4). Error bars indicate standard deviation.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/104/9/10.1182_blood-2004-01-0112/6/zh80210468680006.jpeg?Expires=1763431834&Signature=RnuxJXEe4xVkDvV8CVO4~fyuOQEvAkTfcgxjl-RfC5Vrro80KGQRDVE4kRlZUh-9FTnMKhdCvfhav5wikB-Ht2A2Rx4sbk0uHWnfS2-G6uqjSUl6FFd9PAAZ8p7f~IdxLxpRFODPlooS~~RrdzTQC3X~vGYRHRU7LeklS2EpPI48r2t4hFbHHJmSnB3XgKqq0eocxgR6NuB0XTY~KGMvPCIhXSz-6NKEd4VBJmQcnE354eb8Tcr2Mf-uMmOhWr9im~REDBxzpkEtJCvLuFM-DrE7sZrZZQzXQLR~2GO-nRaVHEd6oSeMdrWJrr01KqOJ4k7jhdydiotWsvyWw9LZag__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Figure 6.
Effect of DTT on KCC activation by cell swelling in SS RBCs. (A) Rb influx activated by pH in SS RBCs with (•) and without (♦) preincubation with DTT (10 mM). DTT was present at 1 mM during nystatin treatment and Rb influx measurement. Data represent 4 independent experiments. (B) Normalized fluxes using maximal volume-stimulated flux (MCHC < 270 g/L [27 g/dL]) of control or DTT-treated SS RBCs. (C) Regulatory volume decrease in SS reticulocytes induced by cell swelling (to MCHC of 260 g/L [26 g/dL]) with and without DTT (n = 4). Error bars indicate standard deviation.
