Fig. 3. Systemic NHL 18 months after MCD diagnosis in patient 7. / Initial lymph node biopsy shows the typical Castleman lesion (A) and the positive staining with the KSHV/HHV8 LNA-1 specific monoclonal antibody (B). Postmortem spleen analysis reveals diffuse infiltration with large/anaplastic cells (C), with positive staining with the KSHV/HHV8 LNA-1 antibody (D), an illegitimate expression of the T-cell CD3 marker (E), and the expression of the CD30 marker (F). Original magnification ×200 in panels A, B, D-F; ×400 in C.
Fig. 3.

Systemic NHL 18 months after MCD diagnosis in patient 7.

Initial lymph node biopsy shows the typical Castleman lesion (A) and the positive staining with the KSHV/HHV8 LNA-1 specific monoclonal antibody (B). Postmortem spleen analysis reveals diffuse infiltration with large/anaplastic cells (C), with positive staining with the KSHV/HHV8 LNA-1 antibody (D), an illegitimate expression of the T-cell CD3 marker (E), and the expression of the CD30 marker (F). Original magnification ×200 in panels A, B, D-F; ×400 in C.

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