Chemokinetic effect of IL-10 and chemotactic effect of SDF-1 on peritoneal B1a lymphocytes.

Peritoneal cells were labeled with CD19, CD5, and Mac-1 mAbs and tested for migration in Transwell experiments. SDF-1 or IL-10 was added to either the lower chamber or to both the lower and upper chambers. Results shown (mean ± SEM from 5 experiments) are the numbers of B1a cells migrating to the lower chamber. *P < .05 compared with cells migrating in response to SDF-1 added alone to the lower chamber. Similar findings were observed for peritoneal B1b and B2 cells.