Fig. 3. Lymphocyte activation and CD95 sensitivity during chemotherapy. / PBLs were analyzed for expression of CD69 (A, B) and sensitivity for CD95-induced apoptosis (C, D) before the first (1st) and consecutive (2nd/3rd) cycles of chemotherapy (A, C) and during the acute phase of lymphocyte depletion of the first cycle (B, D). Percentage of CD69+ cells of CD4 cells is depicted (A, B). MNCs were cultured in medium with and without death-inducing anti-CD95. Percentage of CD4 cells positive for annexin V was measured after 24 hours, and the percentage of CD95-specific cell death is given in the graphs (B, D).
Fig. 3.

Lymphocyte activation and CD95 sensitivity during chemotherapy.

PBLs were analyzed for expression of CD69 (A, B) and sensitivity for CD95-induced apoptosis (C, D) before the first (1st) and consecutive (2nd/3rd) cycles of chemotherapy (A, C) and during the acute phase of lymphocyte depletion of the first cycle (B, D). Percentage of CD69+ cells of CD4 cells is depicted (A, B). MNCs were cultured in medium with and without death-inducing anti-CD95. Percentage of CD4 cells positive for annexin V was measured after 24 hours, and the percentage of CD95-specific cell death is given in the graphs (B, D).

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