Structural comparison of ITD and internal tandem triplication in the

FLT3 gene. (A) ITD within exon 11 from patient 55. Three nucleotides (TTG = Leu) are inserted prior to the duplication of codons 579 to 593. (B) A novel internal tandem triplication within exon 11 from patient 8. Three nucleotides (TTC = Phe) are inserted prior to duplication of codons 602 to 612. Codons 603 to 612 are duplicated again, forming a triplication of codons 603 to 609.