Fig. 2. Effect of priming on cytogenetics in BM and PB. Marrow was obtained before priming and PB and BM were obtained after priming on protocols CY/GM/BM, MAC/G/PB, and CY/G/PB from all ECP and AP CML patients. Marrow and PB cells were evaluated by metaphase analysis to detect the number of Ph-positive metaphases. On average, 20 metaphases from steady-state marrow, mobilized marrow, or PB collections were analyzed. For PB collections, the average percent of Ph-positive metaphases in all collections was entered in the figure. Results are depicted for all samples that were analyzed and divided as follows: (□), major cytogenetic response, 0% to 30% of metaphases or cells Ph positive; (▧), minor cytogenetic response, 30% to 90% of metaphases or cells Ph positive; (▪), no response, 90% to 100% of metaphases or cells Ph positive.
Fig. 2.

Effect of priming on cytogenetics in BM and PB. Marrow was obtained before priming and PB and BM were obtained after priming on protocols CY/GM/BM, MAC/G/PB, and CY/G/PB from all ECP and AP CML patients. Marrow and PB cells were evaluated by metaphase analysis to detect the number of Ph-positive metaphases. On average, 20 metaphases from steady-state marrow, mobilized marrow, or PB collections were analyzed. For PB collections, the average percent of Ph-positive metaphases in all collections was entered in the figure. Results are depicted for all samples that were analyzed and divided as follows: (□), major cytogenetic response, 0% to 30% of metaphases or cells Ph positive; (▧), minor cytogenetic response, 30% to 90% of metaphases or cells Ph positive; (▪), no response, 90% to 100% of metaphases or cells Ph positive.

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