Figure 5.
Location of predicted binding sites for EBV miR in the 3′UTRs of PD-L1 and PD-L2. Diagram indicates general location of 6 putative binding sites of EBV miR-BART19-3p and EBV miR-BHRF1-2-5p in the 3′UTRs of the PD-L1 and PD-L2 genes. On PD-L1, EBV miR-BART19-3p site 1 is closest to the 3′UTR, with EBV miR-BHRF1-2-5p ∼1800 nt downstream, possessing the highest free energy and score for this gene. For PD-L2, EBV miR-BHRF1-2-5p site 1 is closest to the 3′UTR and has the highest free energy and score for this gene. EBV miR-BHRF1-2-5p site 2 is only 7 nt downstream of site 1, and EBV miR-BART19-3p is the farthest away, being just under 1000 nt downstream of EBV miR-BHRF1-2-5p site 2.

Location of predicted binding sites for EBV miR in the 3′UTRs of PD-L1 and PD-L2. Diagram indicates general location of 6 putative binding sites of EBV miR-BART19-3p and EBV miR-BHRF1-2-5p in the 3′UTRs of the PD-L1 and PD-L2 genes. On PD-L1, EBV miR-BART19-3p site 1 is closest to the 3′UTR, with EBV miR-BHRF1-2-5p ∼1800 nt downstream, possessing the highest free energy and score for this gene. For PD-L2, EBV miR-BHRF1-2-5p site 1 is closest to the 3′UTR and has the highest free energy and score for this gene. EBV miR-BHRF1-2-5p site 2 is only 7 nt downstream of site 1, and EBV miR-BART19-3p is the farthest away, being just under 1000 nt downstream of EBV miR-BHRF1-2-5p site 2.

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