Figure 3. Kinetics of the JAK2V617F mutation during progression to blast phase in a patient with primary myelofibrosis. Serial analysis of marrow blast percentage and JAK2V617F mutation load showed extinction of the JAK2V617F-bearing clone during blast phase progression. In this patient, the JAK2V617F and the blast phase clones were clearly independent disease processes.
Figure 3

Kinetics of the JAK2V617F mutation during progression to blast phase in a patient with primary myelofibrosis. Serial analysis of marrow blast percentage and JAK2V617F mutation load showed extinction of the JAK2V617F-bearing clone during blast phase progression. In this patient, the JAK2V617F and the blast phase clones were clearly independent disease processes.

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