Somatic mutations have variable frequencies across age groups. Mutations most commonly found in adults are noted in green. Mutations most commonly found in AYAs are noted in red print. Mutations most commonly found in children are in blue print. FLT3-ITD (black) mutations occurred in nearly equal frequency across the age groups. Inset, blood film of acute myelogenous leukemia; multiple myeloblasts, one contains a prominent Auer rod. (Wright-Giemsa stain; original magnification ×1000).