Figure 1. Mechanisms of novel hemophilia therapies. (A) Normal hemostatic balance tipped in favor of bleeding, for example, (B) in hemophilia A from lack of coagulation FVIII. (C) One approach to improve hemostatic balance in hemophilia is to add additional procoagulants; (D) another approach is to remove or inhibit anticoagulants. Adapted from Willyard.64
Figure 1.

Mechanisms of novel hemophilia therapies. (A) Normal hemostatic balance tipped in favor of bleeding, for example, (B) in hemophilia A from lack of coagulation FVIII. (C) One approach to improve hemostatic balance in hemophilia is to add additional procoagulants; (D) another approach is to remove or inhibit anticoagulants. Adapted from Willyard.64 

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