Figure 5.
Figure 5. SnPP administration causes a decrease in α-globin precipitation and improves erythroid cell survival in Th3/+ mice. (A) Representative image and densitometry quantification of a Coomassie blue-stained triton-acetic acid-urea gel loaded with membrane samples isolated from RBC from Wt and Th3/+ mice treated with either PBS or SnPP. (B) Flow cytometry analysis of CFSE-positive RBC derived from Wt + PBS, Wt + SnPP, Th3/+ + PBS, and Th3+ + SnPP groups and injected into Wt animals (n = 4). *P < .05, ***P < .001.

SnPP administration causes a decrease in α-globin precipitation and improves erythroid cell survival in Th3/+mice. (A) Representative image and densitometry quantification of a Coomassie blue-stained triton-acetic acid-urea gel loaded with membrane samples isolated from RBC from Wt and Th3/+ mice treated with either PBS or SnPP. (B) Flow cytometry analysis of CFSE-positive RBC derived from Wt + PBS, Wt + SnPP, Th3/+ + PBS, and Th3+ + SnPP groups and injected into Wt animals (n = 4). *P < .05, ***P < .001.

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