Figure 5. Perifosine enhances cytotoxicity of conventional (Dex, Mel, Dox) agents. MM.1S cells were cultured for 12 hours with control medium (□) and with 2.5 μm(▪) or 5 μm (▪) perifosine in the presence or absence of (A) Dex, 50 nm and 100 nm; (B) Mel, 2-5 μm and 5 μm; and (C) Dox, 50 nm and 100 nm. Cytotoxicity was assessed by MTT assay; data represent the mean plus or minus SD of quadruplicate cultures.
Figure 5.

Perifosine enhances cytotoxicity of conventional (Dex, Mel, Dox) agents. MM.1S cells were cultured for 12 hours with control medium (□) and with 2.5 μm(▪) or 5 μm (▪) perifosine in the presence or absence of (A) Dex, 50 nm and 100 nm; (B) Mel, 2-5 μm and 5 μm; and (C) Dox, 50 nm and 100 nm. Cytotoxicity was assessed by MTT assay; data represent the mean plus or minus SD of quadruplicate cultures.

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