DDAVP response scoring. (A) AS to DDAVP. (B) RR to DDAVP. The AS is a qualitative score based on the peak FVIII:C level: complete (peak ≥0.50 IU/mL), partial (peak ≥0.30 to <0.50 IU/mL), or absent (peak <0.30 IU/mL). The complete AS was further divided into 2 subgroups, <0.8 and ≥0.8, corresponding to FVIII normalization ≥0.50 but <0.8 IU/mL and ≥0.80 IU/mL, respectively. The RR is a qualitative score based on FVIII recovery (peak-to-basal FVIII:C ratio): complete (≥3), partial (≤2 to <3), or absent (<2).