Figure 1.
Diagram representing the 10 most common TP53 mutations identified in AML/MDS.3 Mutations highlighted in red are also among the 5 most commonly mutated residues in overall malignancies. CTD, C-terminal domain; DBD, DNA-binding domain; HD, hinge domain; OD, oligomerization domain; PRR, proline-rich region; TAD, transactivation domain.

Diagram representing the 10 most common TP53 mutations identified in AML/MDS.3 Mutations highlighted in red are also among the 5 most commonly mutated residues in overall malignancies. CTD, C-terminal domain; DBD, DNA-binding domain; HD, hinge domain; OD, oligomerization domain; PRR, proline-rich region; TAD, transactivation domain.

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