Immune differences between BL with granulomatous reaction and BL with typical starry sky. GEP showed that BL with typical starry sky pattern both EBV+ (orange) and EBV– (violet) were enriched in and M2-related chemokines (A), M2 macrophages (B), and immune exhaustion signature (C).

Immune differences between BL with granulomatous reaction and BL with typical starry sky. GEP showed that BL with typical starry sky pattern both EBV+ (orange) and EBV– (violet) were enriched in and M2-related chemokines (A), M2 macrophages (B), and immune exhaustion signature (C).

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