Factors associated with OS in all patients. (A) Kaplan-Meier curve of OS in all patients with NPM1 mutant in AML17 and AML19. (B) Volcano plot of the univariable associations with OS. The HR for age is per 10 years, and WCC and platelets are log-transformed. (C) Multivariable Cox regression analysis of factors associated with OS. The HR for age is per 10 years, and WCC and platelets are log-transformed. ∗Cytogenetic risk is with normal karyotype as the reference group. ^NPM1 mutation type is with type A as the reference group.