Whole BM transplantation in recipient mice. Red blood cells (RBCs), platelets (PLTs), and WBC counts in the PB of: (A) adult SETBP1^LSL and SETBP1^G870S mice; (B) lethally irradiated secondary recipients of SETBP1^LSL and SETBP1^G870S BM, 2 weeks after transplant; (C) sublethally irradiated recipients of SETBP1^LSL and SETBP1^G870S BM, 6 weeks after transplant. Blood cell counts were obtained using a blood analyzer; (D) OS of sublethally irradiated recipients of SETBP1^G870S BM (orange) and SETBP1^LSL BM (green).