Survival outcome for TP53 mutated AML subgroups. Prognostic relevance of mutated TP53 according to (A) variant allele frequency and association with (B) monosomy 17/del(17p), (C) monosomy 5/del(5q), (D) monosomy 7, (E) CK/MK, or (F) an MR gene mutation among patients with de novo AML. Mut, mutated; wt, wild type.